- No Dub for You: Ken's Rage 2, unlike the original, has no English dub. It's Japanese voices only with subtitles.
- The Other Darrin: No one from the anime's voice cast reprises their roles.
- Amiba has a noticably different voice actor in the sequel.
- Relationship Voice Actor: Rei in Ken's Rage is the second role Takehito Koyasu inherited from the late Kaneto Shiozawa - the first being Zato-1.
- Kenshiro, Rei, Ryuken, Souther,Hyou, Sachi and Bat (young) Umeka Shoji are Ikki, Radamathys, Aiolia/Narrator, Camus, Saga/Kanon, Orphee and Kiki.
- Rei and Toki are Ryosuke and Keisuke and Kuroyanagi and Pierrot.
- Kenshiro, Shin, Toki and Bat (Adult) are Oga, Kanzaki, Tojo and Natsume.
- Jagi as Alaindelon.
- Sachi, Shin, Rei, Toki and Raoh are Kou, Hoshi, Sister, Potachi and Billy/Narrator.
- Mamiya, Rei and Toki are Cagalli, La Flaga and Yzak.
- Yuria as Flay, Natarle and Via.
- Shin and Toki are Hideki and Shinbo.
- Souther, Kenshiro, Rei and Toki are Ban, Uryuu & Akutsu, Jubei and Miroku.
- Toki and Souther are Gilgamesh and Lancer.
- Toki and Kaioh are Kanji and Dojima.
- Yuria, Kaioh and Souther are Kasumi, Brad Wong and Jan Lee.
Trivia / Fist of the North Star: Ken's Rage