- Adored by the Network: When this show started airing, it quickly became Nickelodeon's top dog in terms of live-action shows - therefore one of the network's most popular shows. The series' popularity resulted in it being run a lot by Nickelodeon even after the show had ended and lead way to similar shows on Nick.
- And now, almost ten years after it's ended, TeenNick seemed just as infatuated with this show as their parent channel once was. Try turning on TeenNick any given hour of the day, chances are this show or Zoey 101 will be on. On October 28, 2012, TeenNick finally realized people were likely annoyed with the constant re-runs so it was taken off the schedule. Then the show returned to TeenNick's schedule that December, though only in the overnight hours, showing the network has moved on...to milking other shows.
- Billing Displacement: In airings of the Christmas Special, Miranda Cosgrove and Jerry Trainor (Carly and Spencer from iCarly) are emphasized more. Some commercials will actually say "Starring Miranda Cosgrove and Jerry Trainor", even though Jerry Trainor is at most an Ascended Extra.
- The Cast Showoff: Drake Bell. It is as if the audience needs constant reminders that Drake Bell has a music career.
- The Danza: The eponymous characters.
- Directed by Cast Member: Drake Bell directed the first part of Really Big Shrimp, while Josh Peck directed the episode Battle of Panthatar.
- Dyeing for Your Art: Drake Bell dyed (get it) his dark brown hair auburn for the show.
- Name's the Same: This Crazy Steve doesn't kidnap Dick Grayson, Age 12.
- The Other Darrin: Frances Callier infamously filled in as Helen in Little Diva when Yvette Nicole Brown was unavailable since she was busy appearing in the ABC sitcom The Big House, which starred a then-unknown Kevin Hart.
- The Other Marty: When the show's pilot was remade into the proper first episode, Jonathan Goldstein took over the role of Walter Nichols from Stephen Furst (of Animal House fame) and stayed in the role for the rest of the series.
- Out of Holiday Episode: The special Merry Christmas, Drake & Josh was Adored by the Network for a while by Nickelodeon, airing even when it was no longer Christmas.
- Reality Subtext: Josh's weight loss is brought up during the Christmas Episode. Josh Peck lost weight during the last two seasons after having a chubby figure in the first two seasons and ultimately looking slimmer in the final season.
- Retroactive Recognition: Four years before her Star-Making Role in Star Wars: The Clone Wars, Ashley Eckstein (at the time under her maiden name Ashley Drane) played Susan, one of Drake's love interests in the episode "Believe Me, Brother".
- Romance on the Set: Denied. It was rumored for years that Jonathan Goldstein and Nancy Sullivan (Walter and Audrey) had gotten married in real life after meeting on the set. However, Josh Peck dismissed the rumor as 100% not true but a really cute idea in 2016.
- Schedule Slip: Drake Bell's car accident in December 2005 caused production of the fourth season to be postponed for three months, with three episodes shot before hand.
- Screwed by the Lawyers: The reason why some episodes of the show are missing from Hulu and iTunes.
Trivia / Drake & Josh