- Channel Hop: The first season aired on Bravo in the USA, while the second season, subtitled Betty: The Betty Broderick Story, aired on USA Network.
- Fake American: The Australian Eric Bana as John Meehan, and Canadian Kevin Zegers as Debra's nephew Toby.
- Real Song Theme Tune: In Season 2, the first episode's theme song is "When You Were Mine" by Cyndi Lauper.
- Variations on a Theme Song: Season 2's theme song starts as "When You Were Mine" by Cyndi Lauper. Over the course of the season, the theme song is replaced with a similar-sounding upbeat '80s tune before gradually degrading to ominous droning.
Trivia / Dirty John