- During Iron Man's preview episode, Death Battle initially made an error in attributing the origin story of Tony's adoptive brother Arno Stark to Tony himself. The video was then taken down and re-uploaded with the correct information.
- This episode was entirely researched by Ben Singer (Wiz), the Death Battle research team had no part in gathering information.
- During the animation, various objects from pop culture appeared in the warehouse. These include: Dragon Balls, a Keyblade, Kryptonite, a Gundam, a Metal Gear, and the Batmobile.
- This episode aired on the week of the US release of Avengers: Age of Ultron. Clips from that movie were shown when discussing Tony's Hulkbuster armor.
- The tune that plays in the background while Tony is working on his suit is the theme to Iron Man: Armored Adventures.
- The music that plays in the background during the final portions of the fight (specifically after Tony dons the Endo-Sym armor) is taken from Aldnoah.Zero.
- Tony's "playing human" quote is a direct quote from a comic involving him wearing the Endo-sym armor.
Trivia / Death Battle S 02 E 21 Iron Man Vs Lex Luthor