- Fan Nickname:
- Follow the Leader: To the Super Smash Bros. series.
- The Other Darrin: Several characters, at least in the original 3DS version, were played by different actors from the ones they had in the shows they originated from. The updated XL version recast most, but not all, characters with their original voice actors.
- Yuri Lowenthal replaces Thurop Van Orman as Flapjack, Benjamin Diskin as Numbuh One, David Coburn as Captain Planet, and Greg Cipes as Kevin Levin.
- Grey DeLisle voices Mac instead of Sean Marquette, Blossom instead of Cathy Cavadini, and Buttercup instead of Elizabeth Daily.
- Tara Strong replaces Candi Milo as the voice of Cheese and Dexternote , Nicky Jones as the voice of Chowder, and Ashley Johnson as the voice of Gwen Tennyson.
- Neil Kaplan replaces Greg Eagles as the voice of Grim and Jeff Bennett as the voice of Johnny Bravo.
- Fred Tatasciore replaces James Remar as Alien Force/Ultimate Alien era Vilgax, Dee Bradley Baker as Ultimate Humongosaur, and the late Mako as Aku.
- Keith Ferguson replaces Phil La Marr as the voice of Samurai Jack.
- Nolan North replaces Brian Doyle-Murray as Captain K'nuckles, Maurice LaMarche as Father, Roger L. Jackson as Mojo Jojo, Diedrich Bader as Hoss Delgado, and Dana Snyder as Gazpacho.
- Quinton Flynn replaces Richard Steven Horvitz as Billy and Dee Bradley Baker as the Toiletnator.
- Talking to Himself: See above.
- What Could Have Been:
- Unused narrator voice clips suggest that Mandark, Schnitzel and the Remote Control were all intended to be playable characters at some point in development.
- In addition to the former two, character icons for Stickybeard, Wilt and Gwen have been found in the game files, though what role they may have played is unknown.
Trivia / Cartoon Network: Punch Time Explosion