- Channel Hop: The bulk of the Bosko cartoons were made at Warner Bros., but Hugh Harman and Rudy Ising left the studio around 1933 for MGM, and took the rights to the character with them. The last 9 Bosko shorts were made at the MGM studio, as part of the Happy Harmonies series.
- Creator Backlash: Friz Freleng, who animated on the Bosko cartoons before becoming the main director of Looney Tunes, said years later that he didn't think much of the cartoons in hindsight, feeling that Bosko had no personality and that Harman-Ising were more concerned with polishing their art instead of making interesting characters. And apparently, none of the original animators liked working on the Buddy cartoons.
- Name's the Same: A 1960's Bugs Bunny short would also share the name of "Dumb Patrol", which was also the name of an early Bosko short.
- The Other Darrin: Bosko was voiced by animator Max Maxwell for his first couple of shorts, then by John Murray for the remainder of Harman-Ising's tenure at Warner Bros. After they moved to MGM, Maxwell took over his voice again until he was redesigned into a human, upon which Ruby Dandridge started vocing him. In his Tiny Toons appearance, Don Messick voiced Bosko.
- Shrug of God: In an interview, co-creator Rudy Ising (and animator Mel Shaw) expressed uncertainty about Bosko's species, but they both denied that the original Bosko was meant to be a blackface character.
"We never knew what he [Bosko] was. A lot of people who saw the films thought Bosko was a little colored boy, but we never thought of him that way. He was just a character with a Southern voice. When Rochelle Hudson did the dialogue for Honey, she used a Southern voice, too. She and Maxwell did wear blackface makeup, but that was part of our recording process. We shot them in live action at the same time we recorded the dialogue, then we studied the footage on a Moviola. Each animator also had a mirror in which he studied his own mouth movements. By the time we learned how to read the voice tracks, we had made charts of lip motions."