- Acting for Two:
- Nick Kroll voices up to twelve characters, including Nick Birch, Maurice the Hormone Monster (doing a pitch-perfect Will Arnett impression), and Coach Steve, the last of whom even reuses Kroll's voice for Douche.
- Maya Rudolph's characters include Nick's mom Diane and Connie the Hormone Monstress.
- Jordan Peele voices the Ghost of Duke Ellington, a Santa Claus character played by Tyler Perry, Freddie Mercury, and Patrick Ewing.
- All-Star Cast: The show definitely prides in its cast, with names like Nick Kroll, John Mulaney, Jessi Klein, Jason Mantzoukas, Jenny Slate, Fred Armisen, Maya Rudolph, Jordan Peele and Richard Kind, with appearances from Andrew Rannells, Kristen Bell, Kristen Wiig, Jon Hamm, and Nathan Fillion. Season 2 adds David Thewlis and Gina Rodriguez.
- The Cast Show Off:
- Maya Rudolph gets to show off her singing voice in "Girls Get Horny Too." This happens again in season two with her song "I Love My Body".
- Jenny Slate gets to sing in "Requiem For A Wet Dream."
- The Danza: Nick Kroll plays Nick Birch and Jessi Klein plays Jessi Glaser. Season 2 adds Gina Rodriguez as Gina Alvarez.
- This also happens in the French dub, where Nick is dubbed by Nicolas Matthys.
- Dawson Casting: None of the actors playing teenagers are under the age of 30. In fact, the whole reason the show is animated is to allow a certain level of detachment that would make it too difficult to go far enough. Lampshaded in the season 1 finale.Nick: Isn't [a show about a bunch of kids masturbating] basically just, like, child pornography?Maurice: Holy shit, I hope not! I mean, maybe if it's animated, we can get away with it. (glances at the fourth wall) Right?
- Descended Creator: Co-creator Nick Kroll plays Nick Birch.
- The Wiki Rule: The Big Mouth Wiki.
Trivia / Big Mouth