- California Doubling: The opening and jungle scenes were filmed in Venezuela, while the rest of the film was shot in Cambria, California.
- Completely Different Title: In Sweden the movie is known as "Imse vimse spindel" translating as "Itsy Bitsy Spider".
- Dueling Dubs: The first Latin American dub of the film was produced in Los Angeles for an initial VHS release. The second dub was produced in Mexico for the DVD release and all other releases since.
- Fake American: Alberta-born Frances Bay plays the Californian Evelyn Metcalf.
- Follow the Leader: Kingdom of the Spiders.
- What Could Have Been:
- Originally, Arachnophobia was meant to be a straight-up horror film. However, both Jeff Daniels and Frank Marshall wanted to make the film "a black comedy with a more ironic tone" and the script went through several rewrites, most notably including the addition of Ross Jennings's fear of spiders. The end result of the film's script included both horror and comedic elements.
- The ending of the film was originally going to reference The Birds, but Steven Spielberg nixed that idea.
- When the film was going to be redubbed for a DVD release in Latin America, voice actress Alma Wilheleme was going to direct the dub at Mexico City's Made in Spanish studio. However, it turned out that Wilheleme also suffers from arachnophobia in real-life and consequently, she decided not to direct it. Gabriel Cobayassi, Made in Spanish's founder and a veteran voice actor in his own right, would eventually direct the dub.
Trivia / Arachnophobia