- Acting for Two: Seth Rogen plays both Herschel and Ben.
- Channel Hop: HBO Max acquired distribution rights to the film from Sony Pictures in early 2020 due to the COVID-19 Pandemic preventing a US theatrical release. It thus became the first Max Original film. It was still theatrically released in some countries such as the UK.
- Dyeing for Your Art: Rogen not being a fan of fake beards, grew a real one. He shaved it to shoot Bens scenes but he came up with a new 15 second scene, requiring Rogen to spend another 10 months to regrow it to shoot it.
- Fake Nationality: Seth Rogen is Canadian-American and plays the Eastern European Herschel. He also plays his fully American great-grandson Ben.
- What Could Have Been: Rogen had doubts about playing two parts so he brought in Ike Barinholtz to read for Herschel and considered having him play the role.
Trivia / An American Pickle