- Disabled Character, Disabled Actor: Lucien has one arm. Jamel Debbouze, who plays him, has a withered right hand (the result of being struck by a train in 1990) which he consistently keeps hidden in a pocket. It's conceivable that, while the character of Lucien being "slow" was always the main excuse given by the grocer for being such a giant Jerkass to him, the missing arm was more of a way to explain Jamel's recognizable posture in-universe that they decided to throw in.
- Doing It for the Art: Before shooting each scene, each on-location set was cleared of all debris, rubbish and graffiti to help convey the fantastical nature of the story. Even the train station.
- Dyeing for Your Art: Audrey Tautou had long hair when she was cast - and had it cut into Amelie's distinctive bob.
- From Entertainment to Education: The film is widely used in French classes to help learn the language as well as provide some entertainment.
- Money, Dear Boy: Director, Jean-Pierre Jeunet distances himself from the musical and only sold the rights to raise money for the children's charity, Mécénat Chirurgie Cardiaque.
- Screen-to-Stage Adaptation: The musical.
- Star-Making Role: For Audrey Tautou. However, it did have the effect of typecasting her as a Manic Pixie Dream Girl.
- Unbuilt Casting Type: Although Audrey Tautou plays a Manic Pixie Dream Girl, she is the protagonist. Her quirks are shown to stem from traumas in her childhood. And although she fixes other people's lives, she is too afraid to fix her own. She and her love interest don't even share the screen until their Last Minute Hook Up.
- What Could Have Been: Amélie was originally intended to be played by Emily Watson, but because Emily had trouble speaking French and did not want to be away from home, the role went to Audrey Tautou. The character of Amelie, is, however, named after her.
- Why Fandom Can't Have Nice Things: The garden gnome was given to the Cafe Des Deux Moulins as a gift after the film wrapped. But when it was stolen, the cafe changed the chairs inside to avoid them being stolen too.
Trivia / Amélie