- Pinkie's Heroic BSoD.
- Chapter 9. Specifically, when Rainbow Dash has her wings broken by a thug and passes out, only to later wake up and find Mare-Do-Well crying over her while she attempts to patch them up. "I'm sorry. I'm sorry. I'm sorry. I'm so sorry."
- Rainbow Dash rejecting Pinkie Pie.
- Pinkie Pie after The Reveal. Not only is she mentally fragile, but she knows exactly how bad it is. She's completely unable to help herself and is convinced that she's damaged beyond repair.
- Chapter 21. It's painful seeing Rainbow Dash and Pinkie Pie (to a lesser extent) exchanging verbal barbs with each other, calling each other out on what they did during the story. You wonder for most of the chapter if their formerly strong friendship will survive at all. Turns into a Heartwarming Moment when Rainbow Dash refuses to give up on Pinkie as a friend.
Tear Jerker / The Games We Play (Friendship Is Magic)