Tear Jerker / Splinter Cell: Double Agent

• The intro, where Sam learns his daughter was killed, and drops his iconic goggles out of the side of the Osprey into the ocean.
• In the Gen 6 version, Sam starts to care for Enrica Villablanca. At the end of the game, she is shot by another splinter cell and dies in Sam's arms. He strikes down the assassin in a fit of rage.
• Lambert's murder at the hands of the JBA. Especially cruel is the Gen 7 version when you are ordered to pull the trigger on your boss. Even if you take the other route and kill Jamie Washington instead, it makes no difference; the next game confirms Lambert met his end "in a dirty New York basement".