- Pretty much the entirety of "Diagnosis of Exclusion", which shows the aftermath of Gina's death and Malaya's sexual assault.
- The ending scene of "The Son Rises", with the cast of The Lion King singing to a terminal patient as he dies.
- Leanne's reaction to Charlotte's death. The look on her face is just....
- Mario breaking down in Angus' arms after his father dies.
- The Reveal in "Unfinished Business."
- Campbell's reaction to losing Heather in "Fallen Angels". And Mario's reaction. And everybody's reaction.
- Leanne and Ariel being pulled apart in "The Devil's Workshop", as Ariel desperately begs for help and Leanne fights to stay with her.
- Ariel's pleading sobs for Leanne to stay with her when Leanne seems to be dying.
- Caitlin Canty's heartbreaking rendition of "Stand By Me", with Jillian Murray reading the Hippocratic Oath as Heather dies.
- The death of Jesse's brother.
Tear Jerker / Code Black