Hugh Dennis of Mock the Week fame is the host, managing a rotating cast of comedians that include guest performers from Mock the Week, some new faces and even the occasional American Whose Line/Improvaganza alumnus, such as Wayne Brady and Jonathan Mangum.
After it was discontinued, the show was heavily retooled and sent to America as Trust Us with Your Life.
- Bald of Awesome: David Armand.
- The Big Guy: Justin Edwards, Greg Davies, and Tom Parry. Humphrey Ker has the height for it though.
- British Brevity: Single-digit episode count.
- Butt-Monkey: Marek Larewood is basically this show's Jonathan Mangum.
- The Cast Showoff: David Armand plays the Interpretive Dance segment.
- Wayne and Jonathan get to play several musical numbers too.
- Episode 6 ended with Ruth, Justin, Pippa, Humphrey, and David doing a Les Misérables-styled parody of I'm A Celebrity.
- Casting Gag: Possibly for Hugh Dennis, whose old-school BBC-announcer voice gets extra airtime as he doubles up as host and announcer.
- Catchphrase: "Ladies and gentlemen, for the next X seconds at least, you're watching Fast And Loose!"
- "Would you please welcome your host, a man who sounds a lot like me— Hugh Dennis!"
- Deliberately Monochrome: "Early TV", meant to present how recent TV shows would be like if they were created in the '40s.
- Getting Crap Past the Radar: Happens at the end of "Right Way, Wrong Way", when Tom stands up and tells Ruth, "Well, it's not going to suck itself, is it?"
- Overly Long Gag: One game of "Forward/Reverse" basically had Jonathan doing the same full-on kiss with Jess, over and over. This Crosses the Line Twice when Wayne gets subjected to the same thing... with Humphrey Ker.
- Happens in another "Forward/Reverse", when Tom and Pippa were made to do the same full-on kiss over and over, resulting in Tom stating that his back was going.
- Precision F-Strike: Justin is the resident master.
- Sophisticated as Hell: Some of the cards have apparently been written just to get this out of Hugh.
- Strictly Formula: Moreso than Whose Line and even Mock The Week — all-player games start the show, "Sideways Scene" always ends the show (except for episode 6), and this time 'quickie' games, usually a quick Q&A session involving no more than three of the players, are used to fill up time between the usual games.
- Writing Around Trademarks: Several new games involve taking the premise wholesale from other actual shows, so this happens a lot ("Weak Links", "Dragon's Lair" etc.)