A Way Out sees Leo do this once he learns that Vincent was an undercover cop the entire journey and wants to bring him back into custody. He takes Vincent hostage, steals a police car, steals a boat, steals a gun from another police officer to try and kill Vincent and beats the living shit out of him on a rooftop. And depending on how well Leo's player does in those sequences, it all leads up to Leo killing his former friend.
Ace Combat 5: The Unsung War: Gives us a 3 person variant when the enemy forces finally manage to kill off Chopper. The enemy pilots get to savour a few seconds of relieved cheering mainly along the lines of "see, they're not invincible after all!"... At which point you and the rest of the squadron proceed to unleash pure hell upon every enemy unit in sight as payback. By the time the mission's over, the few surviving opponents are almost literally running away crying for their mommies. It gets to the point that, if you're flying particularly well in that mission, by the time reinforcements arrive, they may have nothing to fight.
There's also an earlier mission in which the Grabacr squadron (still disguised as the phony Osean 8492nd) assault a Yuke college, getting Wardog (and therefore, Osea) the blame. In return for getting Yuke civilians killed, Yuktobania retaliate by gassing a town full of college students and having a transport squad carrying tanks attack a civilian airport in Osea.
American McGee's Grimm: "Cinderella was not simply an ill-used ninny who married well, forgave her tormentors, and lived happily ever after. She was innocent, she was abused, she was harmed. HER PAIN SHOULD BE PAID FOR!"
The final episode implies that the story Snow White and the Seven Dwarves is also Grimm's own - that he was the eighth dwarf who, living under the shadow of happy-ending-experiencing royalty, was mocked by the townsfolk for his unpleasant appearance and rank odor, slew everyone in town in revenge and began a long rampage through the worlds of fiction.
Assassin's Creed II: Ezio starts out with the family business of killing people in revenge for the death of his father and two brothers. Then it extends to that family's bosses, and their bosses, right up and into the Ancient Conspiracy central to the game, for over thirty years. To reword Seanbaby:
At the time, the country of Italy was using Ezio Auditore to control the aristocrat population and they occasionally dragged him on a chain through the air to hunt Templars in the least humane way possible.
In a bit of a subversion, however, by the last quarter of the game, Ezio is shown to be getting tired of his constant desire for revenge, which dovetails neatly into his plan to set up the Assassins Brotherhood to oppose the Templars systematically rather than in a reactionary way in Brotherhood and Revelations.
In Brotherhood, he finally stops and spares the one who caused it all. Sparing Borgia turns out to be a bad idea after all, when Rodrigo's psychotic son comes looking for payback, against dad's advice.
He does this again in Revelations when he finds out about Yusuf's death and Sofia's kidnapping.
Connor from Assassin's Creed III also performs one against Charles Lee for burning his village and killing his mother. Only to find out that Charles Lee is innocent of the burndown. The one who really did it was no other than Connor's idol, George Washington.
Assassin's Creed: Unity is this for both Arno and Elise as they track down who was responsible for her father's murder.
Assassin's Creed Origins is about Bayek and his wife Aya hunting down the members of the Order of the Ancients who were directly involved in the death of their son Khemu. At the end of the game, finding that their revenge does not feel satisfied and not really at peace with the death of their son, Bayek and Aya set up the foundations of the Assassin Brotherhood in Egypt and Italy to hunt down everyone else in the Order of the Ancients, which in essence makes the whole Assassin Brotherhood one long revenge scheme against the Templars for the death of Khemu.
Assassin's Creed: Odyssey: The third act of the DLC "Legacy of the First Blade" is the player character going Mama Bear / Papa Wolf (delete where appropriate) on the Order of Ancients for killing their love and abducting their baby.
Asura's Wrath: Asura out rivals EVERYONE on this entire Trope page when it comes to this. He will stop at NOTHING to get his daughter back. He takes this EVEN FURTHER when a girl that looks like the daughter his is trying to save is killed by the Seven Deities along with her entire village by destroying the ENTIRE FLEET that Olga sent to destroy said village. If anyone represents the Patron Saint of this trope, it's Asura.
Bacon Man: An Adventure is about the titular character taking vengeance against everyone who framed him for his grandfather's murder.
Borderlands 2: Mordecai has a big one after Handsome Jack mutates his pet Bloodwing and kills her. Normally, Mordecai uses a sniper rifle with a slag effect, but after the event happens, he screams at the top of his lungs and blasts the Hyperion robots with explosive shots, stronger than the game's standard explosive element and strong enough to take out the robots in a single hit. Later on, Mordecai has you attack Hyperion's wildlife labs in revenge.
All of the experience when playing as Krieg's is this when fighting Hyperion, who brutally experimented on him to give him his superhuman abilities but broke his mind in the process. Getting payback against Hyperion is one of a very small number of things both sides of his mind can agree on.
Good!Krieg: Yes. Make them pay for what they did to us.
The Fury status, a battle mechanic unique to Shrimp and Cornelia. If theyre both in the active party, and one of them goes down, then the other will get a massive stat boost across the board.
On a plot-related note, we have Caties arch-nemesis Boxxyfan. He may have died in the first game, but not really. His mad thirst for revenge is fueling his Virtual Ghost, the Pale Wraith, which continues plaguing our heroine throughout the sequel. Also, near the end, we finally get to see what happened to make him that way in the first place: the destruction of his home and family due to an accident Catie causes while time traveling.
Bulletstorm: The entire background for Grayson Hunt, the anti-hero protagonist, consists of this somewhat mixed with He Who Fights Monsters. Grayson's unit was employed for assassinations of innocent civilians (such as reporters) by the Big Bad of the game, a seemingly insane, utterly ruthless general, apparently for personal gains. However, the nature of the targets was not revealed to the team, who believed they were eliminating terrorists, pirates, slavers and so on. After finding out that they have been used as killers, Grayson vows to kill said general, defects (together with his men) from the army...and becomes a pirate himself, descending into almost psychotic aggression, fueled by alcoholism. Just how far he is willing to go is exemplified by the beginning of the game: he crashes his ship into a military cruiser, believing the antagonist to be on board (plausible, as it's the flagship of the fleet) in a suicide attack - sacrificing his own crew (save for one person) and taking into account the deaths of over a thousand (the number is explicitly stated) enemy crewmen whose only fault is to be on board of the ship his enemy is on.
"Dust to Dust", the final level, revolves around Price and Yuri avenging Soap. The first half of this level isn't so much "Roaring Rampage" as it is "Implacable Man slowly marches". Yuri goes even further, trying to redeem himself for having previously served Makarov. Too bad Redemption Equals Death.
Dark Messiah of Might and Magic: If the player is trying to achieve the good ending, Leanna appears to be killed by the Necromancer Arantir, when the player arrives at his lair later the guards almost seem afraid of the player's wrath as he becomes an unstoppable juggernaught of revenge, the player can then rescue her from the lair to get the good ending.
Darksiders: The entire premise of this game is that the Horseman of War is on a quest to kill the ones responsible for his fall from grace. Samael even honors his deal with War when he could easily betray him because he actually respects a good ol' Roaring Rampage of Revenge. When he discovers that the Charred Council made him their Unwitting Pawn and faked his fall from grace in a breach of the pact he and the rest of the Horsemen obey, he decides to go after them with the help of his fellow Horsemen.
Diablo III: The Nephalem goes on two of these during the course of the game.
The first one is triggered two thirds of the way into the first act of the game when Deckard Cain is killed by Maghda and the Dark Coven and continues into the first part of Act II.
The second, bigger one occurs during the second part of Reaper of Souls when Adria resurfaces following her disappearance through a portal at the end of Act III after turning Leah, her own daughter, into the vessel for Diablo to be reborn as the Prime Evil in by far the cruelest betrayal of the entire series.
Dissidia Final Fantasy: After beating the main story, you can select SNK boss Chaos in quick battles, set him to level one, and then select a level 100 character. Proceed to curbstomps for every last retry you were forced to endure in story mode.
DOOM (2016): Artifacts in Hell tell the story of the Doom Slayer (i.e., the player character), who stormed Hell seeking vengeance for various wrongs caused by the demons. His rampage was so epic, bloodthirsty, and flat out unstoppable, he ended up terrifying the very legions of Hell. In the end, the demons barely managed seal him away. He is eventually awakened in the current game to stop the latest incursion of Hell, and his merciless crusade to exterminate the demons of Hell shows absolutely no sign of stopping.
Direct sequel Doom Eternalreveals the Doom Slayer is actually the Doom Marine from the original Doom games and heavily implies that much of his unyielding hatred of demons is because they killed his pet rabbit Daisy in the ending of the first game.
Dynasty Warriors: In every game, Liu Bei and Zhang Fei get sent into this when they find out that Wu has assassinated Guan Yu and Guan Ping. Result: a Genocide leaving no one in Wu alive.
In any map with Lu Bu and Diaochan; if you kill Diaochan first...Lu Bu loses his shit, gets massive stat boosts and will chase you across the entire map to try and kill you.
A prominent example in the series' backstory occurred when the Falmer (Snow Elves) slaughtered and burnt the (supposedlypeaceful) Atmoran (proto-Nord) city of Saarthal. Ysgramor and his sons returned to Atmora to raise an army. Gathering 500 of Atmora's greatest warriors, they returned and nearly drove the Falmer to extinction. Later, Ysgramor's Papa Wolf traits showed up once again when his son, Yngol, was taken by the "sea ghosts". Ysgramor became aware of this and demanded the ghosts set him free; in response, the ghosts summoned a terrible storm. Ysgramor fearlessly strode into it and defeated each of the ghosts, only to find Yngol and his clan dead. Filled with grief, he vented his rage on 24 of the fiercest monsters in Skyrim, slaying them all in honor of his kin. He then ordered a great barrow to be dug for Yngol and his clansmen's resting place.
You can do this if you join the Stormcloak rebellion. The perspective of a player character in that scenario is that the Empire was about to execute him/her at the beginning of the game for being a Stormcloak even though the player had no prior involvement with them.
You can also go on a rampage against the Dark Brotherhood after killing Astrid, though you will have to visit Aventus Aretino and kill Grelod the Kind for him. Given the number of assassins that she likes to send after you during the course of your quest, you'll most likely want to do something about them.
The Thieves' Guild questline turns into one of these after Mercer Frey betrays you in Snow Veil Sanctum, and really picks up steam when the other Guild members learn that he's robbed the guild and is singlehandedly responsible for the downturn their fortunes have taken.
The final Dark Brotherhood quest, Hail Sithis, which has you going after the Emperor, has a side mission involving taking out Commander Maro, who was responsible for intimidating Astrid into betraying you, and then having the Falkreath Sanctuary destroyed and many of your Dark Brothers and Sisters killed, something which many players will undoubtedly want Maro dead for.
The Companions questline has you going on one along with Vilkas after the Silver Hand assault Jorrvaskr and kill Kodlak Whitemane.
The Lights Out quest has you going on a heist with Jaree-Ra, who wants to run a ship aground and make off with its treasure. Despite his promise to leave the crew alive, his Blackblood Marauders have already murdered everyone on board when you arrive, and when you get to the treasure, you learn they've made off with it already and that Jaree and Deeja never intended to give you a cut or let you live. The rest of the quest is an object lesson in why you do not betray the Dragonborn.
If you have the "Hearthfire" expansion, you can rampage against the bandits who have taken your wife/husband hostage from one of your plots of land, starting with the messenger.
In Fallen London, players with the Nemesis ambition are essentially enacting a long-term version of this trope, having sent themselves down to the Neath via arrest to be able to hunt down the murderer of a loved one. They can subvert it, however, by choosing to spare the people involved in their loved one's murder instead of exacting revenge on them, including the murderer himself who turns out to have only been a pawn in a much larger scheme and doesn't resist if you do choose to kill him.
Fallout: New Vegas: Craig Boone devotes his life to destroying the Legion, who bought his wife as a slave and forced him to perform a Mercy Kill on her, and will sign up to aid you if you promise him the opportunity to fight against them.
Courier: Any thoughts on Caesar's Legion?
Boone: Lots of thoughts. All about the best ways to kill them.
Also a way to play the Courier if you decide to head straight for Benny without stopping for anything along the way. However, you cannot kill Yes Man, who masterminded your murder (though he only knows you're the Courier he helped kill if you tell him, at which point he apologizes) due to the fact that he is one of the few immortal NPCs of the game, albeit with justification. He apologizes for this as well, telling you that your revenge must feel empty because of this. As a small consolation, he points out that you can destroy his physical body as many times as you please.
There is also a small workaround to this. If Yes-Man is disintegrated with an energy weapon, the game does not respawn him, thus fulfilling the Courier's bloodthirsty quest for vengeance. Unfortunately, if they have already killed the leaders of the other factions, there is no possible way to complete the game. Everyone remains trapped in a static existence for the rest of time. Hope that revenge was worth it...
Final Fantasy VI: After his wife, his son, and his king (along with almost everyone else in Doma castle) are killed by Kefka's poison, Cyan rampages through the Imperial camp. Partly subverted in that Sabin and Shadow come to Cyan's aid and the three end up escaping from the camp.
Final Fantasy VII: Sephiroth learns the "truth" that he's a descendent of the ancients, then goes berserk & burns down the town of Nibelheim. He later learns the truth behind the "truth," but continues with his plan to become a God, transferring "descendent of the Ancients" to "descendent of Jenova." A good deal of his actions—which also become his downfall—are also that he wants to get revenge on Cloud for defeating him in a fairly humiliating fashion.
Delita's reaction to his sister's murder. It is to be noted while he acts that way towards the immediate person who dealt the killing blow, his revenge on the corrupt society behind the killing was much more planned.
Zalbaag goes into a murderous rage against his brother Dycedarg, when he learns that their father's death was caused by Dycedarg secretly poisoning him.
Meliadoul's reason for trying to destroy Ramza is because she thinks he was the responsible for his brother Isilud's death. She stops when she finds out who is the real murderer.
Argath has a less subtle version which crosses the Moral Event Horizon. After being resurrected by the Lucavi, he loudly declares to Ramza that he's going to kill all of the lower class, presumably in part to get back at Delita for killing him.
In Fire Emblem: Three Houses, on all routes except Crimson Flower, Dimitri goes completely insane when he discovers Edelgard is the Flame Emperor, who he believes was responsible for the deaths of his friends and family in the Tragedy of Duscur. He spends over five years mindlessly slaughtering every Adrestian soldier he can get his hands on and becomes obsessed with tearing their head from their shoulders. It's deconstructed in that he neglects his duty to his kingdom and drives away his friends due to his obsession with revenge, and his rampage ultimately ends at the Battle at Gronder with either his untimely death on the Silver Snow and Verdant Wind routes or a Heel Realization and decision to abandon his revenge and atone on the Azure Moon route.
In Gems of War, Sapphira, a vampire aristocrat in Whitehelm, was attacked by the religious authorities despite traditionally being at peace with them, and doesn't know what has changed. She's quite pissed off, and isn't the type to take it quietly; her retaliation involves fighting large numbers of holy warriors and burning down a temple. (She does eventually accept arrest, but un-accepts it when a proper trial isn't forthcoming.)
Ghost Trick: The Big Bad spends years carrying out a meticulously crafted plan to punish everyone involved with his death, including the then-young girl he took hostage.
The Godfather: This game is essentially one of these for player character Aldo Trapani. Don Emilio Barzini had your father killed. You get recruited as a Corleone hatchetman. It's convenient that the Corleone goals of taking over NYC and crushing the other four families align with your own.
Revenge is the central theme in God of War. Pretty much boils down to this: If they've crossed Kratos, they're going to die. Along with anyone and anything that stands in his way. Including Fate itself.
Also a deconstruction, as Kratos' unrelenting desire for revenge ultimately has dire consequences, showing how one man's desire for revenge can destroy everything that he once held dear (first, his family is destroyed because he wanted revenge against the man who defeated him in battle, and then, ultimately, the whole world suffers for his devastating rampage).
Grand Theft Auto: Chinatown Wars: An early mission involves driving through the turf of rival dealers while your employer opens up on everybody with a machine gun in retaliation for stolen business. Oh, and a previous mission involves tracking down someone who cheated him and cutting his heart out.
Grand Theft Auto IV: The final mission of the game will always be this, with Niko seeking revenge either on Dimitri Rascalov for killing Roman or on Jimmy Pegorino for killing Kate, murdering several mooks in the process.
Half-Life 2: Gordon Freeman enters the enemy base, alone, at the end of the game. All his weapons are taken from him, except for the Gravity Gun, which becomes ultra-powered and capable of even grabbing enemy soldiers. All his friends have been captured. The entire end-game segment lets the player go berserk on the enemy with the Gravity Gun, torturing and maiming them in every way imaginable, while Dr. Breen, his old supervisor, calls him worthless.
Hunters form bonded pairs with one another and always fight together. If one goes down, the other will furiously redouble its efforts to reduce you to a bloody pulp.
The Precursors, after denying the Forerunners the Mantle in favor of humanity, are hunted to near extinction by a massive Forerunner military force. A few escape though, and were understandably not happy. Their plan? Make sure that everything they've ever created suffers for all eternity. The form they took to accomplish this? The Flood.
Haunting Starring Polterguy: Poltergeist Polterguy's motivation is to remorselessly scare Vito and his family out of their house because Vito's company produced crappy skateboards (Polterguy died riding one of these). He is completely merciless with them.
Heavenly Sword: This game has Nariko going on one of these when King Bohan kidnaps her father. She literally tears through his entire army to get at him.
House of the Dead: OVERKILL: The exact words of the trope name are used by the narrator when describing Varla's motivation. (Her brother turned himself into a monster while trying to kill Papa Caesar, so she wants Papa Caesar dead. The heroes are the ones who actually killed her brother, but it was a I Cannot Self-Terminate, so they don't get the blame.)
Infamous Second Son has two examples. First, Fetch accidentally killed her brother in a drug-induced rage and has been targeting and killing drug dealers ever since. Second, during an attempt to rescue Fetch and Eugene from the D.U.P. that turns out to be an ambush, Augustine murders Reggie in cold blood. Delsin doesNOThandle this well.
In Insaniquarium, the reason Itchy the swordfish is so eager to kill the aliens is that all his friends were once devoured by one of them. Now he wants them all dead.
And while we're on the topic of Kingdom Hearts, Roxas in 358/2 Days. He was forced to kill and absorb one of his best friends, so he ends up going on a one-man invasion of the entire World That Never Was to set Kingdom Hearts free and put Organization XIII in their place, easily taking out Neo Shadows in a single hit. And throughout all of this his memories of Xion are fading, to the point that when he begins his battle with Riku he only remembers his best friend as "her". Unfortunately for Roxas, Riku puts a stop to his rampage before he can even get to the Castle That Never Was. In the end, it was probably for the best. If Riku managed to defeat Roxas when he wasn't even trying to kill him, Xemnas and company would have been much less merciful. And if Roxas got himself killed, a semi-deceased Sora would've been taken down along with him.
Another one with Roxas in Kingdom Hearts II. Axel is implied to have kidnapped Kairi in order to draw out Sora and turn him into a Heartless in order to release Roxas (his best friend) from Sora, as Sora and Roxas are one and the same. He nevertheless makes a Heroic Sacrifice of his own choice to save Sora when fighting alongside him. Roxas learns of this and stages a battle for control of Sora's sense of self out of turmoil for losing Axel due to Sora in a way. He comes at Sora with a killing intent, while emotional music blares in the background; doing everything short of crying Broken Tears. He loses, and relents to his fate, but Sora has none of this, insists Roxas is his own person, and vows to bring him back. He succeeded, with the help of Vexen and Zexion.
Kingpin: Life of Crime: the main character is brutally beaten by thugs working for Nikki Blanco, and he's told never to come back. Instead, he sets across the landscape, destroying the Mafia run businesses, killing numerous members, and going after Nikki's boss to finally take control for himself.
Kirby: Squeak Squad. Cake is stolen? Go beat up Dedede! Dedede doesn't have the cake, but some thieves do? Go beat them up! Treasure chest does not contain cake? Beat up the thing that's in it!
Laura Bow: The Colonel's Bequest: The actual good ending tells you that Lillian did this.
Legacy of Kain: Soul Reaver: The vampire Raziel is brutally mutilated, rebuked, and tossed into oblivion...but that's just how the story starts. Once he gets back up, Raziel gets to work his way up through his younger brothers, leading straight up to Kain himself.
This is something of a running theme in the Legacy of Kain series. First game opens with secondary character Vorador slaughtering six of the most powerful people in the world out of revenge; the game itself is Kain's rampage of revenge. In Soul Reaver 2, Raziel goes on another one against the mortal forms of himself and his brothers in the past, and Blood Omen 2 features Kain on yet another rampage.
The Legend of Heroes: Trails of Cold Steel III has Rean Schwarzer who, after seeing Millium dying at the Nameless One's hands, loses control of his Superpowered Evil Side and starts slicing and dicing the Nameless One, long after he kills it. And this wasn't enough to sate his hunger for revenge as he goes directly to the source: his father.
In some Adventure Mode missions, a Mama Cucco and a Cucco Chick will appear, and you're asked to escort the Chick to its Mama. If the Chick gets killed, the Mama Cucco goes crazy, gets the highest powerup status possible, and starts attacking both sides (mostly yours).
Also in Adventure Mode, you will occasionally be tasked with escorting an injured soldier back to base. If you fail, he comes back as a vengeful ghost. Though his rampage isn't as physically devastating as the mama cucco's, he can lay some nasty curses on you if left sitting around too long, like dropping your allies' morale, stealing your rupees, or even making your allies vanish from battle (and it's possible to instantly lose the battle if one of your playable allies are cursed to vanish).
Lugaru: Basically the entirety of this game, by the end of the game, nearly every named character has been revealed as a traitor.
Liara T'Soni becomes obsessed with Shepard to the point where she is willing to work with Cerberus after the Collector attack. When the Shadow Broker tries to sell Shepard out to the Collecters Liara does not take it well, and starts working with criminals, Asari commandos, threatening to kill her contacts with their own spine, all to get back at the Shadow Broker. When she finds out that her friend Feron, who was captured and presumed killed by the Shadow Broker, is alive, however, her motive rapidly change from revenge to rescue...with a revenge flavor.
Zaeed has a similar motive against Vido Santiago, who betrayed Zaeed by turning their men against him, and paying six of them to hold him down while he put one right through Zaeed's skull. During his Loyalty Mission, Zaeed causes a fire that endangers a crowd of civilians in the pursuit of his vengeance against Vido, which leaves Shepard with the choice of saving the civilians or helping Zaeed take his revenge.
If you've given Commander Shepard the Colonist background and the Ruthless reputation, then it's implied that what Shepard did to the batarian slavers of Torfan was vengeance for Mindoir.
Thane Krios has one of these in his back story. When his wife, who he had met by having her interpose herself between his gun and his target, is assassinated by slavers trying to strike back at him; he snaps and hunts them ALL down:
Thane: I was taught to grant death quickly, cleanly, to minimize suffering. Them, I let them linger.
Could be a trait of Asari. The UnfetteredCombat Pragmatist Aria gets kicked out of her home base on Omega by Cerberus in Mass Effect 3, but doesn't really care about an intricate plan to get back at them:
Shepard: How do you plan on getting Omega back? Aria: I think I am going to employ violence.
Garrus's men (when he was Archangel) are this as well.
Shepard storming Cerberus headquarters near the end of the game considering how they constantly manipulated him/her in the previous game and tried to destroy all of his/her efforts for the war in 3. Especially when s/he guts Kai Leng like a fish for killing Thane, Miranda or Kirrahe.
In the first game, the title character goes on one of these after his partner, Alex Balder is killed and he is framed for it. He starts with Jack Lupino, the guy he considers responsible, moves on to Lupino's boss, Punchinello, and then sets his sights on Nicole Horne when it's discovered that she was behind not only Alex's murder and the frame up (pulled off by dirty cop and Dragon B.B.), but also the murder of Max's wife and baby girl by V-head junkies three years ago.
Max Payne 2 picks up before he starts his next rampage. It isn't until the 3rd and final chapter of the game that he goes from reactionary, self-defense killing to actively hunting down those who wronged him. And everybody dies.
The third game continues the theme: Max is hired as a private bodyguard in South America. When his charge is kidnapped despite his best efforts, Max is told that he can't go up against the criminal cartel, there's too many of them and they have too much power. Max gears up anyway.
Mercenaries 2: Ramon Solano, the Big Bad, might have come out on top, had he not pulled a You Have Outlived Your Usefulness on the player merc by refusing to pay them, trying to kill them to preemptively stop any attempt to claim the bounty on his head, and to add insult to injury, causing them to get shot in the ass. This triggers a rampage across Venezuela that results in countless VZ casualties, billions of dollars in property damage, one destroyed castle, a few leveled cities, and two nuclear strikes.
Super Metroid: The final battle against Mother Brain depicts her destroying the Metroid Larva, which was trying to protect Samus in the first place. As it dies, it gives Samus the Hyper Beam, an insanely-powered, wall-piercing rainbow gun. So Samus, after being thrown around by Mother Brain like a chew toy, turns the tables and goes on a rampage against her, reducing Mother Brain to dust, and the planet Zebes soon after.
Metroid: Other M adds another level to it by giving it a cutscene to show just how pissed off Samus really was.
Practically every encounter she has with Space Pirates, particularly Ridley, could turn into a Roaring Rampage of Revenge. In the backstory, they destroyed the colony where she lived and killed everyone else, including her parents (one of whom was ripped apart and eaten by Ridley right in front of her). Yeah, the Pirates have a damn good reason to be afraid whenever "The Hunter" shows up.
Mortal Kombat: This game has a lot of characters with revenge as a motive. The best known probably being series mascot Scorpion; a spectral ninja whose story in the first game revolved around killing Sub-Zero, the man who killed him, his clan, and his wife and son. As it turns out, Sub-Zero only killed Scorpion; his family and clan were killed by Quan Chi, the sorceror who allowed him to seek revenge against Sub-Zero. When Scorpion finds this out, he switches targets to seeking revenge on Quan Chi.
Kung Lao is the first to discover Liu Kang's body in Deadly Alliance after the eponymous pair snap his neck. He vows revenge against the duo and seeks an old master to train for their defeat. It doesn't end well for him either, in spite of that. The roles are reversed in Mortal Kombat 9, wherein Kung Lao successfully defeats every challenger Shao Kahn puts before him until Kahn himself simply walks up behind him and breaks his neck. Liu Kang then challenges Kahn and this time puts a fiery fist right through his chest.
Ninja Gaiden: Although he remains chillingly calm about it, the remake is all about Ryu Hayabusa putting his blade through the many minions of the Vigoor Empire that razed his village and killed off almost all of his kin.
However, because of the way the UAA functions, the game serves as a deconstruction of the "work your way up to the big bad" plot. Travis' target is rank 1 in the UAA, so Travis has to slaughter a whole bunch of people to face him, almost all of them of them people he's never even met. By the time he can actually face his target, he's grown disgusted by all the killing and swears vengeance not just for his dead friend, but for all the people he's had to kill, vowing to bring down the ranked assassination scene and stop the mindless bloodshed.
If you skip more than one day of work by being with your family in One Chance, an angry co-worker will try to murder you when you show up the next day after everyone else in the place had been Driven to Suicide. Defend yourself against him, and he'll run off into your house, murdering your wife and daughter before hanging himself by the time you get home.
Outlaws: Retired Marshall Anderson goes after the people who kill his wife and take his daughter, methodically hunting them down one after another and put them to frontier justice. He also finds his father's killer and shoots him in the process.
Onmyōji: After Tamamo no Mae loses his wife, he spends roughly a decade raising his twin children until they too are slain by an onmyōji. The event pushes him through the Despair Event Horizon and he is now still burning down entire villages in search of the murderer.
Pony Island: Subverted. For stealing his seat as guardian of a system core file, Buer swears vengeance upon Asmodeus. But he's completely impotent and powerless to do anything about his sorry lot. Even worse, Asmodeus knows this.
In Prison Architect, your dog handlers and their dogs are considered separate entities who work in tandem, and can be damaged separately in combat. If the handler dies fighting a prisoner, the dog will actually track down the prisoner who killed their handler and try to kill them in revenge.
[PROTOTYPE]: To quote Alex Mercer: "NOTHING CAN PROTECT YOU FROM ME! NOT MEN! NOT WEAPONS! NOT ARMOR!". And the guy about to get consumed? Was a jerkass, but definitely not at the top of Alex's hit list.
Quintessence - The Blighted Venom: Reivier Wirt goes on a killing rampage after his wife supposedly dies. Complete with Hidden Eyes.
The Reconstruction: Dehl goes on one in chapter 6 after having a Freak Out that causes his personality to invert. This temporary personality change makes some of his skill descriptions read almost like black comedy.
"The serene, peaceful nature of the knight manifests in enhanced inner traits."
A deconstruction of this trope is present in Red Dead Redemption. The protagonist John is shot and killed in the ending by the corrupt cop Edgar Ross, prompting his grown-up son Jack on one of these for the game's epilogue. Here's where the deconstruction comes in: before John's death, Jack was a kind-hearted, idealistic young man with dreams of becoming a writer. Afterwards, Jack becomes a jaded gunslinger outlaw on the run from the government, drifting from place to place with his former life in ruins. While he eventually succeeds in getting revenge on Ross, it doesn't matter in the end, because Ross is remembered as a hero, John is remembered as a brutal criminal who was brought to justice, and Jack has to spend the rest of his days as a depressed, wandering loner, trapped in a gun-slinging lifestyle that is quickly dying out. Damnit.
Actually, things might not have turned out so bad. In Grand Theft Auto V, you can find a book in Franklin's house entitled Red Dead by J. Marston, implying that Jack managed to find some measure of peace with himself after all, and became a writer just as his dad wanted.
The gang gets a major one when John's son Jack gets kidnapped. In mere hours, one of the two local ruling families is thoroughly destroyed. The entire gang (minus non-combatants) rides up to the mansion, one of the only times everyone joins in for a mission, and proceed to massacre the guards. When its confirmed Jack isn't there, the mansion is burned to the ground, and the head matriarch is brought down from leader of one of the most powerful families in the area to reduced to a crying mess and commits suicide by running into her own burning mansion to die by fire.
Ironically, John himself is on the giving end of one of these. The game's original protagonist, Arthur Morgan, discovered that the van der Linde gang's Token Evil Teammate, Micah Bell, was a traitor and the reason the gang fell apart in the first place. In all endings, Micah fights and badly beats the already-dying Arthur, and in the two less honorable endings, kills Arthur himself (and even in the best ending, in which Arthur succumbs to his disease, the beating he received from Micah certainly hastened his impending death). Eight years later, John (whom Arthur helped escape from Micah), along with Charles and Sadie, former fellow gang members and close friends of both his and Arthur's, go on one of these against Micah to get payback for both Arthur's sake and for him destroying the gang. They succeed, but unfortunately, John coming out of hiding to kill Micah puts him on Ross's radar, setting up the events of the first game.
The plot of Rune focuses on Ragnar hunting down a viking who betrayed his comrades to side with Loki and killed them.
Saints Row 2: The latter part of the Brotherhood storyline (for both sides), an excellent example of why having someone actually roar and rampage is a lot better than being calm and deliberate when you're the one they want revenge on.
A large part of the plot of Saints Row: The Third is about revenge. The Saints are out to avenge the death of Johnny Gat, first targeting Philip Loren, before going after Killbane. The individual members of your crew are motivated to avenge some sort of wrong, and the ending you get depends on if you are willing to let your vengeance go, or pursue it at the cost of all else.
Sengoku Basara 3: Ishida Mitsunari is out to kill Tokugawa Ieyasu in revenge for his master. No matter what you do, no matter how hard you try, you will not be able to stop him. And God help you if you get in his way. He'll add you to the list.
Shenmue: The entire premise of the game is basically Ryo Hazuki seeking the man who killed his father, despite heartfelt pleas from Fuku-san, Ine-san and Nozomi-chan not to do so. He doesn't really think very clearly, gets in a heap of trouble frequently through ill-thought-out actions and goes after the more shady inhabitants of Yokosuka and Kowloon with varying degrees of competence. However, if you kidnap someone he's close to, then prepare for pain. One time he kicks the living crap out of 70 people to get fix things.
Sins of a Solar Empire: You have an entire star nation going on a Roaring Rampage of Revenge; the Advent. You see, the Advent's ancestors were a religious order on a remote desert planet that was experimenting with cybernetic implants and Psychic Powers in an attempt to unite humanity in a peaceful coexistent society when they were found by the Trade Order. The "Xenophobic" Trade Order, which was appalled at the wanton Hive Mind and horrific biological experimentation the Advent were performing on a cultural level. So they exiled the Advent into deep space without first taking away or destroying their psychic and cybernetic research. Predictably, the Advent continue to develop those technologies and build a formidable empire with a large fleet of some very powerful warships outside Trader space; all the while brooding over their mistreatment and exile. A few generations later the first Advent fleets cross back into Trader space intent on reclaiming their homeworld and punishing the Trade Order (now known as the Trader Emergency Coalation-TEC).
It doesn't work, the TEC fighting back through a combination of willpower, industry, and logistical expertise, against both afforementioned Advent and the alien Vasari. and now, the're pissed. So much so that roughly half the TEC refused any overtures of peace and now are out to eradicate the invaders by any and all means necessary.
Splinter Cell: Conviction: The entire premise is centered around Sam Fisher's hunt to avenge his daughter's murder. Except she wasn't murdered. Her "death" was engineered by Lambert in order to focus Sam on a specific mission. Grim is manipulating Sam with the knowledge that his daughter is alive, in an attempt to get him to help her stop a military coup in the US. Sam agrees, but when the job is done, he makes it clear that if anyone from his past contacts him again, he won't be merciful. And then, in the ending, when his friend is relating the tale to the Black Arrow mercenaries that have captured him, the base is rocked with explosions, as Sam goes to save the last friend he has...
Starcraft: Sarah Kerrigan, over a dozen planets later and she's still getting warmed up. Well, there goes the universe!
In Starcraft II, after the events of Wings of Liberty Kerrigan seems more focused specifically against Arcturus Mengsk, who she deems to have subjected her to a Fate Worse than Death all the way back in the first game.
Star Wars: Battlefront II: Imperial Campaign. It's right after the Battle of Yavin. The Rebellion has destroyed the Death Star, killing untold numbers of your fellow servicemen. Your mission? Payback time. You're going to wipe out every last one you can find and blow their base to bits.
Star Wars' Dark Forces Saga has Kyle Katarn going on three of these, in increasing orders of magnitude.
In one mission in Dark Forces, Kyle and Jan are captured by Jabba the Hutt, and Kyle takes this personally. He kills Jabba's pet Kell dragons with his bare hands, slaughters his entire cadre of mercenaries, shoots up the interior of the space yacht, and strips the crime lord's ship clean of personal equipment and weapons in the process.
In Jedi Knight, he goes on his second one after Jerec and his Dark Jedi after they murdered his father. His bodycount is somewhere in the hundreds, including AT-STs, Kell dragons, most of Nar Shadda, and half a dozen Dark Jedi. The bloody results of this rampage convinces him he needs to cut his ties to the Force.
Kyle goes on his third and bloodiest rampage in Jedi Outcast when Jan Ors is Killed Offscreen to make him go to a source of incredible Force power and unwittingly lead her killers there, only it turns out her death was faked without his knowledge, whereupon Kyle goes into a rage, reconnects with the Force, and winds up with a bodycount somewhere around a thousand this time, including nearly a hundred Reborn Dark Jedi and even more AT-STs. At this point, the number of Dark Jedi he's killed exceeds the number of light-side Jedi that exist at the time of the games. He's considered a One-Man Army for a reason.
According to side-material, Street Fighter's Dan Hibiki went on one towards Sagat after the latter killed his father. When the two meet, however, Sagat allows Dan to beat him to take his revenge, mostly because he realized the doofus was way out of his league and decided to stop him before he hurt himself.
Submachine 8: The Core: all the devastation in the Winter Palace is revealed to have been Murtaugh's fault, because the death toll from his Portal Network tearing everything apart led those affected to those in charge attempting to bury him in the Lighthouse; this didn't turn out so well for those in charge.
Suikoden II: Despite the fact that he is probably one of the most reprehensible villains in video game history, Luca Blight could use this as justification for his actions.
Works for me; it's the only humanizing quality about what would otherwise be an almost cartoonishly evil villain.
Super Robot Wars: After finding out that the Fury basically obliterated everything near her in the beginning of the series, Calvina Coulange in Super Robot Wars Judgment fell into this trope, intensely hating every Furies she came across and mercilessly slaughtering all Furies that come across her, but she didn't do it with a roar. She later made one exception, though.
Also, Fallen Hero Tempest, whose family were killed by the EFA screwing up, and who has joined the Divine Crusaders not to protect the world from aliens or build an empire, but simply to hurt the EFA. As it happens, he doesn't give a damn about the "list", attempting to kill a fourteen-year-old girl despite noting that she was the same age as his daughter would have been.
Tales of Legendia: Chloe Valens heads to the the Legacy in order to track down her parents' killer, a man with a snake tattoo. Any time she even sees his face she flies into a fury.
Tales of Symphonia: Kratos has an epic one when your party fights Kvar, stabbing him and then slashing him in the chest twice, due to what Kvar did to Anna.
Tales of Berseria: The whole story is Velvet Crowe's quest to avenge her brother. By any means necessary.
Tears to Tiara 2: Hamil against Izabel and the Holy Empire. Subverted at Eburon. Hamil pretends to fly into one on seeing Izebel at the beginning of the assault on the bridge of Eburon, but is actually just buying time for the rest of the assault team to destroy the bridge. Once the destruction of the bridge is certain, he almost flies into a real one.
Team Fortress 2: An unlockable shotgun for the Engineer allows you to avenge your turret, giving you two guaranteed Critical Hits for every kill the turret made while it was still around, and one for every kill assist.
Near the beginning of Thor: God of Thunder, a game set before the events of Thor itself, Sif pushes another Asgardian out of the way of danger. She is then impaled and becomes dead for a time, enraging Thor and causing him to seek vengeance for her death.
Odin:(discussing bringing Sif back to life and messing with fate) I may yet forestall slaughter and holocaust. Loki: Your gift to him will surely slake his vengeful thirst, and while you recover in the Odin sleep, I know he will defend Asgard in your stead.
Total War: When that faction you share a border with and have to this point been peaceful trading partners with decides it wants to take that juicy-looking target of a city on their border, the ensuing war can quickly turn into this trope with a little help from the "Exterminate" or "Raze" options (depending on the game) when you not just liberate the city your new enemy just took but conquer all of their cities as well.
In Hidden Star In Four Seasons, the heroine gets humiliated and expelled by the Final Boss at the end of the normal game, so they embark on a second trip to her pocket dimension only to rematch her in the Extra Stage. Heck, even the Extra Stage description (instead of the usual warning to not try this difficulty) explicitly says "Now it's the time for your counterattack!", and the Extra Stage title instead reads Revenging Stage.
Traffic Department 2142: In this DOS game, the main character Lt. Velasquez has been on one of these ever since her father was killed. As the game goes on, her hatred builds, sending her on a downward spiral towards the Moral Event Horizon, before she finally "finds peace" in the form of even her being too tired of killing to go on doing it.
True Crime: Streets of L.A.: The game has an optional story arc in which Nick Kang, on failing to rescue his brother, himself goes on a roaring rampage of revenge to find and kill the man responsible, having already been slightly pushed over the edge by the death of his father prior to the game's beginning. Said rampage leads to one of the "bad endings" in the game, since Nick is left with unanswered questions regarding his own father's fate - the secret dies with the endgame boss.
Viking: Battle for Asgard: They just start piling up very quickly. Rakan joins Hel in destroying the world because Freya spurned him, Skarin goes on his own by fighting his way (offscreen) to Fenrir and releasing him when Freya essentially enslaves him, and Fenrir himself gets one against the Gods for chaining him up in the first place.
War of Omens: Listrata does this with an army after the Siani put her parents to the sword. So far, she's gotten captured one and killed another.
Wet: Rubi is set up by Rupert Pelham, who is in charge of a global drug ring, to take the fall for killing William Ackers's son. How does she get even? This is the page for Roaring Rampage of Revenge, what do you think?
Warframe: This is the Valkyr Warframe personified. After being experimented on and all but skinned by the Corpus (namely Alad V), Valkyr is traumatised and incredibly pissed off; her entire playstyle revolves around screaming bloody murder and using energy claws to rip everything a new one.
Also applies to the Stalker; being one of the few beings who remember what the Tenno did before they all lost their memory, he is on a mission to seek and destroy them all, and he is very much fit for the task.
Watch_Dogs: One of the main plot threads through the game is protagonist Aiden Pearce trying to find and kill everyone involved in the death of his niece.
The sequel, Watch_Dogs 2, has several missions where DedSec's motives skew more into vengeance than justice, but special mention goes to the mission "An Eye of an Eye" where street gang, the Tezcas, murder DedSec member Horatio, prompting Marcus and the rest of DedSec to go on the warpath, not only killing Horatio's killers but destroying a significant amount of the Tezcas product as well.
World of Warcraft: Jaina Proudmoore goes on one after the Horde destroys Theramore, and has to be talked down from destroying Orgrimmar in retaliation. Later, when she's made leader of Dalaran, one of the few places where the Alliance and Horde still coexist peacefully, her trust is betrayed when the Blood Elves use Dalaran as a jump point to invade Darnassus; she then purges the Horde from Dalaran and devotes it and the Kirin-Tor to the Alliance.
X3 Albion Prelude: The entire plot of the game revolves around the Terran's roaring rampage of war and revenge after the Argon Federation blows up the Torus Aeternal, a massive orbital shipyard / city for tens of millions / defense installation that wraps entirely around Earth.
Almost every player character in Xenoblade has a score to settle with the Mechon. Shulk in particular wants Metal Face's head for Fiora's death during the assault on Colony 9, and the entire race scrapped just to be sure. This ends in a subversion, as the turning point of Shulk's Character Development is gaining enough perspective to not be blinded by his need for revenge, turning him into an All-Loving Hero who starts to question why the Mechon act this way.
Xenogears: Id goes on one of these after the villains try to kill the woman he...well, he doesn't exactly love her, but he considers her to be his. He ends up destroying an entire floating city and causing the deaths of at least thousands of innocent people.
To put this in perspective, the city is designed to utterly destroy a full assault from the entire military forces of the rest of the world combined without so much as causing a cup in the city to quiver. Id ripped through the entire city with full defenses operational and firing in roughly ten minutes.
XIII: While it's only a side goal and you'd much rather just take out their head, you still get a list of the conspirators. This is kind of interesting at first as everyone on the list but your traitorous self, even the lowest rankers, are bosses for the first 85% of the game, and it seems like the game is setting up an all-boss rampage like some of the excellent examples above. Unfortunately, you end up killing about half of them in the second last stage, dressed in Klan outfits and equipped with no more AI or HP than the average mook. Oh, and the leader escapes to the sequel that will never be.
This trope is built into the game mechanics for Yandere Simulator. If you kill someone in front of a witness, their reaction will be based on their persona- Dangerous (the Student Council), Strict (Teachers) and Heroic (some students) will attempt to apprehend you themselves, Social Butterflies will run to a place with people (and call the cops), Teachers' Pets will tell their preferred teacher, Loners will run out of school and then call the cops, and Cowards will run away, but not call the police. However, certain students have others that they're particularly close to, like Saki with Kokona, Pippi with Ryuto, the Basu sisters with each other, the Photography club with each other, and anyone you've matchmade with each other. When you kill one of such a pair where the other can see you, it doesn't matter what their personality is- they're coming after you as if they had the Heroic persona. And you'd better be ready for a struggle, because their strength will be maxed out, even if they were incapable of self-defense beforehand.
Naturally, this is the motivation for the Yars in the Older Than the NES game, Yars' Revenge; the Yars are gunning for revenge against another race of aliens called the Qotile, who had destroyed one of their planets; the full backstory was detailed in a comic book that came with the game.
Zyll: Zyll didn't hesitate to embark on this once he discovered the Black Orb.
The Spectrum Retreat has a rather tragic example, as after Robin's death, Alex decides to kill everyone he believes responsible for it, ending in himself, even though everyone involved was little more than a victim of circumstances (with one possible exception). Fortunately, Maddie stops him after the first murder.