Anime & Manga
- Sally the Witch: The original intro features a mischievous bipedal mouse that gets chased by a cat that looks like Tom. The cat was originally a brush until Sally transformed it.
- In the Lamput episode "Lamput Checks In", Slim Doc gets cozy in his and Fat Doc's hotel room and turns on the TV. The TV plays a cartoon where a brown mouse is being chased by a gray cat, a likely reference to Tom and Jerry (this is a form of Company Cross References as well, as Lamput and Tom and Jerry are both owned by WarnerMedia companies).
- They are mentioned once in Mafalda when she's tuning in various stations, in the usual style of the comic.Radio 1: "...uy Infrarox, quality in heati-"Mafalda *Changing station*: 'Puff! Publicity!'Radio 2: "...register printed by the bohemian venetia-"Mafalda *Changing station*: 'Puff! Music for elders!'Radio 3: "...rab-Israeli Conflict-"Mafalda *Changing station*: 'Puff! Tom and Jerry!'
- Off the Mark: Jerry appears in this strip◊ alongside like Mickey Mouse, Fievel, Pixie and Dixie, Speedy Gonzales, and StuartLittle. They're discussing whether or not to bring up the subject of growth hormones to Mickey.
- Mother Goose and Grimm: Here◊ we see Attila watching the show and being enraged by it. Grimmy tells him that it's just a show and that he doesn't have to look for any hidden meanings.
- Anchors Aweigh: Joseph tells a group of kids the story of "The King Who Couldn't Dance", seguing into a live-action/cartoon sequence featuring Jerry in the title role and Tom as his butler.
- The role of the king was originally going to be played by Mickey Mouse, but Walt Disney refused permission.
- Dangerous When Wet: In a cartoon dream sequence, Kate dreams of deep-sea diving with Tom and Jerry.
- E.T. the Extra-Terrestrial: A scene from The Mouse Comes to Dinner appears on a TV that E.T. turns on.
- In Moving Pictures, when the magic of Holy Wood starts creating Uplifted Animals, this includes a cat and a mouse. The mouse's first complex thought is "If I picked up that frying pan, I could probably hit the cat with it."
- There's an Inside No. 9 episode epunymously titled "Tom and Gerri".
- A pair of recurring goons in RoboCop: The Series were named after the duo.
- Cracked: The February 2000 issue features a segment called Toon People that mentions Mickey Mouse sharing a mouse hole with Jerry at a toon retirement home.
- According to David Mitchell on The Unbelievable Truth, the symptoms of musophobia, or fear of mice, include "standing on a chair shouting 'Thomas!' in a slightly racist voice".
- Animal Crossing: One of the Show Within A Shows is of a cat-and-mouse cartoon. This creates Furry Confusion and Carnivore Confusion as the games take place in a town almost entirely populated with Funny Animals (some of which are cats and mice).
- In a bit of meta humor, the GPU of the Atari Jaguar was code-named Tom, while the primary sound chip was named Jerry.
- A minor character in Housepets! is Jasper, a blue-grey cat who is usually silent, but occasionally speaks in quotes from the few cartoons where Tom is Suddenly Speaking. He is also constantly tortured by a brown mouse named Jinx.
- In an episode of Console Wars, Greg and Dan see whether the SNES or the Sega Genesis had the worst Licensed Game based on the cartoon.
- The Nostalgia Critic:
- The Critic has reviewed Tom and Jerry: The Movie.
- In his review of Jaws: The Revenge, he notes that the shark's roar is the same one Jerry makes in The Milky Waif.
- In his review of The Cat in the Hat, as a Call-Back to his review of Tom and Jerry: The Movie, when the Cat advertises Universal Studios, the Critic depicts Lickboot saying, "We've got to have money!" in the new Dr. Seuss logo.
- In his review of Fox Kids, the Critic reviews the Tom & Jerry Kids spin-off.
- In the SuperMarioLogan episode, "Bowser Junior Gets Jinxed!", Junior writes an essay about macaroni and cheese. In his essay, he mentions that he thought that Swiss cheese has holes in it because mice would eat holes in it, like in Tom and Jerry. Junior mentions that he likes that show due to its violence, and yet it doesn't get age-restricted. He also questions why Tom doesn't just shoot poison into Jerry's mouse hole.
- Animaniacs: In the short "Cat on a Hot Steel Beam", expies of Tom and Jerry chasing a baby on the same construction site that Mindy and Buttons are on, showing how the Straying Baby trope has been done to death by then.
- Dexter's Laboratory: The episode "Mom and Jerry" has Dexter turned into a mouse by one of his experiments and trying to escape his mom's attempts to catch him.
- The Fairly Oddparents:
- In the TV movie Channel Chasers, Timmy, Adult Timmy, Cosmo, Wanda, and Vicky go through an Affectionate Parody of the show called Ted and Jimmy, with Timmy, Adult Timmy, Cosmo, and Wanda in Jerry's role, and Vicky in Tom's role.
- In "Mice Capades", Timmy and Poof watch an affectionate parody of the show called Sleazy and Cheezy, and later act it out when Wanda won't let them watch it.
- Family Guy:
- In "Road to Rupert", the Anchors Aweigh sequence mentioned above is shown with Stewie drawn over Jerry.
- In "Grumpy Old Man", Babs tells Stewie that they'll call Tom and Jerry when they get home.
- In "Valentine's Day in Quahog", Peter and Lois watch the final episode of Tom and Jerry, in which Tom simply calls an exterminator to get rid of Jerry.
- Garfield and Friends: In "The Cartoon Cat Conspiracy" Garfield is shown a cartoon in which a mouse abuses a cat and is disgusted by it.
- Kim Possible has Scamper & Bitey in the Trapped in TV Land episode.
- In "Mickey Mouse Mouse Exterminator Service", Jerry is among the mice and rats that Mickey captures.
- In "Tom and Jury", Tom is arrested and put on trial for dropping an anvil on Jerry. Tuffy serves as Jerry's lawyer, and Tom is found guilty (due in part to his inability to speak). Kath Soucie reprised her role as Tuffy for this sketch.
- Penn Zero: Part-Time Hero: The episode "A Game of Cat and Mouse" has Penn as a mouse in a space station trying to stop it from going into a black hole, while avoiding Rippen as a cat.
- The Powerpuff Girls: In "Ice Sore", Bubbles tells Blossom to use her newly-discovered ice breath to freeze the kitchen so they can skate in it, "just like Tom and Jerry".
- The Simpsons: The Itchy & Scratchy Show is an over-the-top parody of Tom and Jerry, with the violence amped up with copious amounts of gore.
- "Itchy & Scratchy: The Movie" features a previous incarnation of the duo very similar to Tom & Jerry.
- In the short, "Li'l Sneezer" from the Tiny Toon Adventures episode, "Test Stressed", a picture of a cat named Tom Injury, who is shown being chased by a mouse with a chainsaw, is shown in the Hall of Cartoon Pussycats.