- In The Edge of Seventeen, 13-year-old Nadine unfavorably compares her appearance to Pedro.
- Anna from There's More Than One Way Home finds Napoleon Dynamite delightfully off-beat, even though the subject matter makes her uncomfortable.
- Ben 10: Omniverse, Clyde 5, Ben's never-before-seen cousin, is voiced by John Heder, and is essentially Napoleon Dynamite if he were from the Ben 10 universe.
- South Park: In "Trapped in the Closet", Stan tells Tom Cruise him that he's not as good an actor as Leonardo DiCaprio, Gene Hackman or "that guy who played Napoleon Dynamite".
