Rebel Without a Cause: In one scene, Jim does a Magoo impression to mock his father. This serves as an Actor Allusion, as the father who is played by Magoo's voice, Jim Backus).
Ace Ventura also does a Magoo impersonation in the first movie.
Family Guy: In "We Love You, Conrad", it's revealed that Lindsay Lohan's DUI arrest was the result of her taking the rap for Magoo's bad driving.
Magoo: I'm too old to go to prison! They'll rape me, and I'll never see it coming! No, I won't!
Futurama: In "The Late Philip J. Fry", Bender says to the Professor "Give me the keys, Magoo!".
MAD: The episode "Fantastic Four Christmases / Red and White Collar" features a sketch involving a reality snow called Scroog'd, which is hosted by an Ebenezer resembling Magoo.
Robot Chicken: A sketch from "Garbage Sushi" features Magoo traveling to Japan and unwittingly taking on the Yakuza.
A sketch from "Bionic Cow" features Magoo, fresh from getting Lasik surgery, getting hit by a truck.
In "'Tis the Fifteenth Season", Homer watches Mr. McGrew's Christmas Carol, which inspires him to be a better person during the holidays.
In "Bart vs. Itchy & Scratchy", Bart and his friends boycott a new gender-flipped version of Itchy & Scratchy, and Kearny says he'll lose it if they make a female Mr. Magoo.
In the King of the Hill episode "Traffic Jam" Peggy mentions her nickname for one of her aunts was "Mrs. Magoo" because she couldn't see very well.