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- The Empath: The Luckiest Smurf series story arc "Smurfed Behind" is named after the book series, although, while it has the Smurfs disappearing and Empath and Polaris left behind, it has nothing to do with the Rapture or anything even remotely Christian, besides just one story where the time-traveling Smurfs meet Jesus during the week leading to His crucifixion.
- Mentioned by the main character in Christian Nation as one of the things that conservative Christians (particularly those who espouse Dominion Theology) constantly think about.
- Right Behind and Supergeddon are two books meant to be parodies of the Left Behind series.
- The Simpsons episode "Thank God It's Doomsday" has the Simpsons family watching a movie called Left Below, which was meant to parody Left Behind.