- Dylan Dog referenced the film on more occasions:
- In the first issue, Dylan takes his client to a theater to watch a horror movie marathon, and when An American Werewolf in London is about to begin, Dylan casually mentions that he has seen it fourteen times.
- In issue #37 "The Dream of the Tiger" a tiger, believed to be a were-tiger at first before the The Reveal that it's not, murders people throughout London and in the end wrecks havoc at Piccadilly Circus.
- In issue #72 "The Last Full Moon" a man is stalked and killed in the London subway by the evil human form of the werewolf (who is a reversed kind that is "good" in its wolf form), then towards the end the werewolf causes panic at Piccadilly Circus and decides to end his life by allowing the police to shoot him to death.
- Werewolf by Night: A poster reading "See you next Wednesday" appears in Jacks room in Midnight Sons Unlimited #7, which is director John Landis Creator Thumbprint. Landis directed An American Werewolf in London.
- Black Sheep (2007): The Were-Sheep transformation scene is shot and presented in a way very similar to David's transformation sequence.
- The Last Circus: At the end of the first act, the protagonist escapes the police by running into a forest, completely naked, and survives by eating the corpse of a deer, which is reminiscent of David's first nightmare sequence.
- Shaun of the Dead: The character of Pete is introduced in a shot that recreates the closet mirror Jump Scare scene, with Shaun in David's place and Pete in Jack's.
- X-Men: Apocalypse: Bryan Singer has confirmed that the scene when Angel transforms into Archangel in was inspired by An American Werewolf in London.
- Army of the Dead: Early on in the film, the scene of the Cat Scare followed by the werewolf suddenly attacking and killing Jack is nearly shot-for-shot recreated between two soldiers and a zombie.
- The Dresden Files: In Ghost Story, Evil!Bob's wolfwaffen are said to appear to have been recruited from one of David's nightmares in An American Werewolf in London.
Live Action TV
- Buffy the Vampire Slayer: In "Phases", the sequence in which Oz wakes up naked after his first rampage is an exact shot-for-shot homage of the sequence in which David wakes up after his first night as a werewolf.
- The Amazing World of Gumball: In "The Nuisance", while the rest of the Wattersons painfully turn into humans, Darwin mutates into their pet dog, parodying David's transformation.
- American Dad!: In "Stan Goes on the Pill". Stan's transformation into a woman is based on this film.
- Angry Kid: In "Darkside", the nightmare sequence of David lying on a hospital bed in the woods with a Nightmare Face is parodied, along with other horror movie scenes.
- Big Hero 6: The Series: At the end of "City of Monsters (Part 1)", Karmi's transformation into a monster is accompanied by a shot of her plush chicken pox virus, just like the Mickey Mouse doll during David's transformation.