Mrs. Twombly stands intently at her computer waiting to nab a valuable doorknob on an online auction at the last second, but Fisher Biskit outbids her even later, causing her to scream in frustration. Vinnie and Sunil, watching a monster movie in the day care room, hear Mrs. Twombly and interprets the noise as a werewolf howl. Initially, Mrs. Twombly is not too worried about the setback, if significantly dismayed, figuring that with Fisher's fortunes, he would keep the doorknob safe.
Outside, Whittany and Brittany get handed a big sack of flyers by their father Fisher and told to distribute them. They spot Blythe standing nearby and, trying to get away with not having to work, give the bag to Blythe. She brings it to the Littlest Pet Shop and reads a flyer in Mrs. Twombly's presence, which turns out to be about an open house at his mansion to show off his art collection. Mrs. Twombly decides to attend the open house, figuring the doorknob must be part of the collection. Mrs. Twombly and Blythe dress up in their finest to get there as Roger takes over the duties of The Littlest Pet Shop in their absence.
Before Roger can conduct any repairs to the store, he injures himself and lets out a howl in pain. Vinnie and Sunil hear this too and start to look for the werewolf in the shop. They hear growling coming from Russell and conclude Russell must be the werewolf, though the growling is really coming from Russell's stomach. Vinnie makes a garlic necklace and Sunil finds a mirror, confusing the stereotypes between lycanthropes and vampires, and they regard his attempts to get away as further evidence. When Vinnie pressures Russell about howling at the moon, Zoe intervenes saying that she does it. Vinnie and Sunil find out that Zoe ripped a plush toy apart recently and instead start thinking that both Russell and Zoe are werewolves. In frustration, Zoe distances herself from Russell.
At the open house, Blythe notices Mrs. Twombly and Fisher do not get along. When Mrs. Twombly starts pressing Fisher about the doorknob, Blythe suggests asking the Biskit Twins. Brittany make mention of a new doorknob for Whittany's bathroom, to which Mrs. Twombly scrambles upstairs. As Blythe is about to follow Mrs. Twombly up, a guest causes an accident, spilling cola on her dress, forcing her to look for the restroom too. Mrs. Twombly finds the doorknob, and horrified to see it used as a plain old doorknob, removes it from the door. She hears footsteps and hides, then retreats when Blythe is in sight.
Vinnie and Sunil notice Penny's claws and Pepper's fangs and conclude they must be monsters too. Minka overhears them and inspects Russell for lyanthropy. Vinnie tosses a metal dog dish where Minka, Russell, and Pepper stand, and the three of them duck. Vinnie figures Minka must be a werewolf too as she tried to avoid what they say was silver. This only convinces everyone but Russell that someone in the shop is a werewolf, and the six of them start blaming each other. All of the pets except Russell keep a close eye on each other, waiitng for any suspicious behavior. When Russell yells at them that werewolves don't exist, Vinnie says that it's something a werewolf would say, directing all of the suspicion at Russell.
As Blythe tries to clean the stain, Whittany steps into the restroom for her own reasons and demands Blythe leave. Giving up on the mess, Blythe attempts to leave, but the doorknob falls out, leaving Blythe and Whittany stuck there. Blythe tells Whittany that Roger could fix the door and get them out, but Whittany erupts at the thought of another Baxter coming into the room, asking why Blythe refuses to be their friend. Blythe tells Whittany that she hasn't been too friendly but also mentions that Blythe always wanted a twin sister so she can have someone with some common ground to speak to. Listening honestly for once, Whittany starts to warm up to Blythe. Brittany, still at the base of the stairs, realizes something is wrong and notices Whittany and Blythe giggling together in the bathroom.
Before long, all of the pets save Russell have bunched themselves in a corner. Russell points out that they're all animals, and fur, claws, and sharp teeth are common and perfectly normal among them. He also points out that it's daytime, and the other pets calm down, at least for the most part.
Mrs. Twombly hears Blythe's voice in the bathroom and gives up the doorknob, attaching it back onto the door so it can open. Brittany watches aghast to see Whittany and Blythe chatting happily together and quickly corrects Whittany's behavior. Whittany tells Blythe to leave, and Mrs. Twombly leaves with her.
Back at The Littlest Pet Shop, the pets tell Blythe about how they thought there was a werewolf nearby. Roger, still doing repair work, injures himself again and lets out a howl, causing the pets and Blythe to huddle together.
This episode contains examples of (YMMV entries go here):
- Big "NO!": Mrs. Twombly upon finding out that Fisher bought the doorknob from under her nose.
- Blatant Lies: Sunil says he never doubted Russell for a minute. He spent the entire episode scared of Russell while in his sight. When Russell forgives him with a handshake, Sunil leaps away the moment he comes into physical contact with Russell.
- Call-Back: This episode builds on Mrs. Twombly's love of doorknobs as mentioned in passing in "Gailbreak!" and seen directly in "Mean Isn't Your Color" and "Trading Places."
- In "What's in the Batter?," Sunil says he'd cut down on late-night monster movies. Apparently, he now watches them in the daytime.
- The Biskit Twins talk about being everyone's friends and witness Blythe turning them down in "Blythe's Big Adventure Part 1." In this episode, Whittany attempts to find out why Blythe did what she did.
- Blythe makes an impression of the Biskit Twins again. Doubles as a Chekhov's Gun as she jokes about it to Mrs. Twombly in Act 1, and she does it again to Whittany in Act 3, who begins to realize her flaws through it.
- We get another glimpse of Mrs. Twombly's wall of doorknobs and doorknob-related items.
- Character Development: Whittany begins warming up to Blythe in this episode, as she genuinely does not understand why Blythe does not like associating with her but is interested in knowing. Considering Brittany has shown respect for Blythe in "Blythe's Big Adventure Part 2," this may be a catch-up of sorts for Whittany as a character.
- Continuity Nod: In "Blythe's Big Adventure Part 2," Blythe distributed flyers all around town, to the Biskit Twins' annoyance. This time, it's their turn to distribute flyers.
- Roger gives another shot at playing handyman for The Littlest Pet Shop. Just as he screwed up then, Blythe tells Roger to be careful.
- Deadly Gaze: Parodied. Blythe warns Mrs. Twombly not to look into the eyes of a painting of the Biskit Twins.
- Door Dumb: Whittany attempts to push against the door to open it when stuck inside, even though the door swings inward into the bathroom.
- Double Entendre: Mrs. Twombly as the auction comes towards its end.Mrs. Twombly: I can't wait to hold you in my hand and turn you!
- Exact WordsWhittany: This is my bathroom, just like everything else in this house.Blythe: Everything else in this house is your bathroom?
- Getting Crap Past the Radar: After Roger injures his foot, his pretending to be fine looks a lot like someone who just got hit in the groin.
- Imagine Spot: While the pets get one in this episode, as is standard procedure, Mrs. Twombly gets one this time too.
- Impossibly Tacky Clothes: Mrs. Twombly's choice of attire when going to the party.
- Magic Countdown: The auction countdown goes from 26 seconds to 21 seconds in just three seconds, then from 19 seconds to the last five seconds in just 8 seconds.
- No Sense of Personal Space: Vinnie and Sunil are a bit too close to their suspects when searching for the werewolf. Also to each other.
- Only Sane Man: Russell is the only one trying to stop Vinnie and Sunil from suspecting everyone of lycanthropy. He is powerless against their infectious paranoia and instead becomes their primary suspect.
- Out of Character: Mentioned by Blythe as she reads the flyers, as she considers it unusual for Fisher to allow people in and out of his mansion.
- Security Cling: Vinnie and Sunil do it a lot.
- Sesquipedalian Loquaciousness: Russell uses the term "lycanthrope," the technical term for were-beings. Vinnie doesn't know what it means. Russell tries to explain it but stops himself knowing Vinnie and Sunil won't understand.
- Shout-Out: This isn't the only episode Corey Powell has written for The Hub about a character taking something out of greed, causing trouble for other characters because of it, and having to relinquish it to fix the mess.
- Mrs. Twombly refers to the doorknob as her "precious." She starts talking like Smeagol when she finds it in the mansion.
- This was likely coincidential, but this episode's B-story involves a lycanthropic hedgehog. The term "werehog" never gets used, however.
- The painting of the Biskit Twins Mrs. Twombly and Blythe see upon entering the mansion resembles Napoleon Crossing the Alps.
- Roger sings a parody of "Hammertime!"
- "Wolf-i-fied" is a take on Michael Jackson's "Thriller."
- Brittany senses a disturbance in the force.
- "The howl is coming from inside the pet shop!"
- Stealth Pun: Roger Drops the Hammer on his foot.
- What do doorknobs and werewolves have in common? They involve a lot of turning.
- The Rival: How Mrs. Twombly and Fisher have come to see each other since Blythe arrived.
- Twin Telepathy: Brittany can sense when something wrong is happening to Whittany. She can also locate her sister by smell.
- Viewer-Friendly Interface: The online auction screen has a countdown taking up one-sixth of the screen, a profile photograph taking up another sixth, and an indicator of whether or not the user has successfully claimed the item taking up another sixth. The picture of the item takes up the middle third, leaving a bunch of text for the remaining sixth.
- Wilhelm Scream: During the narration right before "Wolf-i-fied."