Deadly attacks on a team of scientists lead Nick, Hank and Wu on an investigation unlike any they have had before. Dr. Hampton is bludgeoned to death in her own laboratory, and the fingerprints of two men who have been dead for months turn up at the crime scene. A visit to her colleague Dr. Raju and former colleague Dr. Shelley reveal that they, along with a Dr. Levy, were researching stem cell tissue regeneration and advanced organ transplant methodologies. When Dr. Raju is killed in a similar manner to Dr. Hampton and evidence of illicit revivification experiments comes to light, it's up to Hank and Wu to figure out who, or what, is tracking down and killing the doctors involved in the project.
Meanwhile, as the research continues into the origins of the cloth, Monroe and Rosalee learn that Eve is still feeling the after effects of the death grip - in that the skeletal portal figure she saw reaches through a mirror and attempts to choke her. Eve woges for the first time since she was healed by the stick, but the confrontation leaves her unconscious and the mirror covered in her blood. Monroe and Rosalee find her and call 911, and Nick leaves the investigation to meet them at the hospital. Nick tells Monroe and Rosalee about the skeletal figure that he and Eve saw.
Elsewhere, Capt. Renard reaches out to an old friend to get answers to the origins of the symbols drawn by Diana.
This episode provides examples of:
- Asshole Victim: The video eventually shows that the victims, Dr Hampton and Dr Raju, were the ones who jumped straight to demanding that their "creation" be killed at once. They also consistently refer to him as "it."
- Beethoven Was an Alien Spy: Studying the celestial carvings in the calendar leads Monroe to sixteenth-century artist and celestial cartographer Giovanni Antonio Vanosino da Varese, who Monroe theorises was a Grimm based on his depictions of the Zodiac animals.
- Call-Back:
- The gang are back to trying to figure out the calendar Eve carved into the tunnel. Having found out about it last episode, Renard is running his own investigation.
- Eve is attacked again by the mirror monster from the previous episode. This time, it's able to reach through the mirror and strangle her.
- The creature's Wesen limbs were from a Huntha Lami Muuaji (left leg), a Pflichttreue (right leg), a Gelumcaedus (right arm) and a Stangebär (left arm).
- Driven to Suicide: After killing his own son, Dr Shelley tries to turn the gun on himself but is stopped by Hank.Hank: No! Not a chance. Somebody's gonna explain this, and it's not gonna be me.
- Flashback: Sitting next to Eve's hospital bed, Nick remembers moments from their relationship, including Aunt Marie telling him to break up with her, his mother telling him not to repeat her mistakes and Trubel shooting Juliette with a crossbow.
- Frankenstein's Monster: Dr. Shelley's son, once the doctors are done rebuilding and reviving him.
- Freudian Slip: When Nick hears that Eve is hurt, he tells Hank and Wu, "Juliette's hurt. I have to go to the hospital." Neither of them miss which name he used.
- Gone Horribly Wrong: The resurrection part actually worked, and without the usual Demonic Possession when a witch caves in, brings the dead back to life, and a strong phantasm latches on in the process. The problem is, they inadvertently used Wesen limbs. The subject goes insane from a combination of woging for the first time, new instincts, and post-resurrection stress, and goes on a killing spree.
- Grave Robbing: How the doctors got the parts to rebuild Shelley's son. Becomes a significant part of the investigation as Hank and Wu try to figure out how the fingerprints of two men who have been dead (and supposedly cremated) for months ended up at the scene of their murder investigation.
- Magical Defibrillator: Played laughably straight: the doctors use a defibrillator to restart the heart of a corpse that's been dead for days (if not weeks - it's not made clear how long they've had the body). A corpse that's had all four limbs replaced with stolen body parts, some from cadavers that have been dead for several months (and some from Wesen corpses).
- Offing the Offspring: Dr Victor Shelley kills his own resurrected son.
- Panicky Expectant Father: Monroe has a nightmare in which Rosalee suddenly goes into labour, with not three babies but at least six.
- Shout-Out:
- The lead doctor's name is Victor Shelley - a reference to the scientist Victor Frankenstein of Frankenstein; or, The Modern Prometheus and the author of the book, Mary Shelley. The whole episode is a homage to the Frankenstein mythos.
- The title is from Ernest Hemingway's novel The Sun Also Rises.
- The opening quote is from "A Vindication of the Rights of Men" by Mary Woolstonecraft, Mary Shelley's mother.
