After Brian breaks his arm, the vet gives him some painkillers...that Lois gets hooked on.
Tropes
- Abusive Parents: Lois nearly drowns Stewie by forcing him to fish out a pill that fell in the toilet.
- Autobots, Rock Out!: Peter and Cleveland have their epic Ping-Pong battle set to Tim Cappello's "I Still Believe", complete with Sexy Sax Man clips from The Lost Boys.
- Brother–Sister Incest: Chris is stalking Meg, who admits she's fine with this because she "loves the attention."
- Call-Back: The way Lois tries to get Stewie to help her is similar to how he's previously tried to get her attention.
- Compressed Vice: Lois becomes addicted to prescription pills and breaks the addiction, but the end implies she's looking for other ways to feel high.
- Dropped in the Toilet: Lois gets addicted to Brian's painkillers. Jonesing for a high, she finds a pill in the bathroom but drops it in the toilet, so she grabs Stewie and sticks him head-first into the toilet to fish out the pill. Fortunately, Brian comes in and saves Stewie before he drowns.
- Epic Fail: During the ping pong match between him and Cleveland, Peter leaps into the air to hit the ball, only to fall down onto the ping pong table and completely destroy it.
- Half the Man He Used to Be: What happens to Esperanza in Lois' Cutaway Gag, a laser from the Target logo in front of the store sliced her vertically in half at high speed, bottom to top.
- Hypocritical Humor: Lois asks a couple of kids she was trying to score drugs off of how they can be so selfish when they've been cleaning up litter and organizing a Black Lives Matter rally instead of dealing her drugs.
- Junkie Parent: Lois becomes addicted to prescription pills.
- Made of Bologna: After being bisected, Esperanza's insides are pinkish red.
- Nightmare Sequence: Lois has one wherein she is naked, falling, and has teeth falling out.
- Mushroom Samba: Lois goes through one of these as a result of withdrawal while locked in Brian's crate.
- Nailed to the Wagon: After Lois becomes addicted to painkillers, Brian locks her in a dog carrier until she overcomes her addiction.
- Pet the Dog: Despite the fact that he can be a pretentious douche (especially in the later seasons) and has unresolved lust for Lois, Brian doesn't use her addiction to his advantage and instead tries to help her overcome it.
- Revenge: After Brian tricks Lois into the crate and locks her in it, Lois tries to get Stewie to open it up and free her. Stewie outright ignores her request, most likely because earlier, she nearly drowned him in the toilet by forcing him to fish a pill out of it.
- Take That!:
- Netflix asks Lois if she's still alive because she watched three non-Michael Scott episodes of The Office (US) in a row.
- Target is depicted as a company that lasers runaway employees to death and no longer accepts change.
- The Cake Is a Lie: Brian tricks Lois into getting into his crate by telling her that there is one last pill in there.
- Tough Love: Brian locks Lois in a crate in order to get her to let go of her drug addiction.
- What the Hell, Hero?: Brian immediately intervenes and calls Lois on her actions when he finds her at risk of drowning Stewie. Similarly, during Lois' withdrawal nightmare, she's condemned for using drugs to get high out of boredom.
