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Anime & Manga

"Be sure to tell Ciel, that if anything happens to my sister I won't forgive him!"
Edward Middleford, Black Butler

"When did I say I would kill you because I'm a soul reaper? The reason why I have killed you is simply because you pointed your blade at my pride."
Byakuya Kuchiki, Bleach

"If you forgot my kid sister's birthday, I'll never forgive you!"
Boruto to Naruto, Boruto: Naruto the Movie

Accelerator: I don't understand ya...that fallen lowlife over there and you...why are you covering for a bunch of dolls? They're failed mass production knock offs of you. The one who should feel most annoyed about that in the whole world is you. You dislike seeing something with the same face as you being broken? That's not something to lose your life over. You can't stand the fact that someone else will reach level 6 before you? Or is this atonement for creating the origin of these experiments?
Mikoto: You think that I care about something like "God's Intellect," or that this is something I could atone for? I don't. They are my sisters. It's because these little girls are my sisters. That's all there is to it.

"Give him back! He's my brother! Take my leg, take my arm, take my heart - anything, you can have it! Just give him back! He's my little brother, he's all I have left!"
Edward Elric, Fullmetal Alchemist

Hades: I only did what was right as the elder brother... by watching over my brothers' backs.
Poseidon: Yes, however... you could very well have been defeated...
Hades: I won't be.
Poseidon: !
Hades: Poseidon... I swear... that I... will not lose to anyone. As the elder brother... I shan't be defeated.

Comic Books

"Lena is my sister, alien... I'm going to save her."

Fan Works

Shirakumo Oboro emerges from the mist like a man back from the grave, and he walks with the same menacing elegance as a ghostly tiger. His hands are clenched into tight fists at his sides, and for the first time since Arashi has seen him, he doesn't see any hint of an emotion in the older man's gaze. Instead, his lips are tight and pursed and his slanted blue eyes glower at the three villains with a kind of menace only a villain can wear. Or, more accurately to say, a very pissed off big brother.
"Twice, Toga, Mr. Compress." Even though his voice is flat, his tone is sharp and cool like a knife pressing against their throats. Dr. Hikigaeru and Arashi stare at the unfamiliar man in shock, meanwhile the villains gape at him as if suddenly realizing their mistake. "Mind telling me what you're doing with my little brother?"

"[My] kid brother is up there," I said, pointing to the speck of the Pool Ship just visible in the sky above us. "And he's surrounded by a hell of a lot of yeerks who all want him dead, and if you don't let me go help him then—" I stopped, not daring to complete the thought out loud. Jake and Rachel would be fine. They had to be.
Eleutherophobia: The Day the Earth Stood Still

Tseng: Can they [Sephiroth and Genesis] overpower him [older Zack]?
Angeal: Normally I would say of course. But today two whole departments lost to a group of toddlers, so...
Younger Zack: Yeah, they're gonna lose. But that's just the power of motivation protecting Cloudy gives ya!

"It's Dean and Sam. It's Oliver and Thea. It's Laurel and Sara. Always and forever. Laurel - much like Dean and Oliver - has made terrible, selfish, impossible choices for her sister. She was willing to destroy, to upend her life, ruin friendships, risk her own soul, just to bring Sara home. She has stripped herself apart to give this girl life, and there has never been one single second where she regretted that.When half of your heart is walking around outside of your body, stuffed into some reckless child who wants to fight the world to save it, you do what you have to do. You keep it beating. When you are an older sibling, you are given a responsibility. You are shown a life that matters so much more than yours. You keep that kid safe. It doesn't matter what you lose in the process or how many things you have to take apart to keep something else together. All that matters is that you do your job."
Laurel on the responsibility of an older sibling, How The Light Gets In

"Please, I don't have time for this right now... my little sister, she's..." He began. In his mind, it was only natural that she would let him past if she understood the situation. He himself had let Chrono past him without a fight when Fate had gotten hurt, hadn't he? It was a big bro's job to protect his baby sister whenever and wherever she needed him. Stopping him from doing that job was just wrong; while he had his doubts as to the morality of some of the actions he'd found himself and his siblings taking recently, that much he knew for sure. Some things were just evil.

Why I felt the need to hide this from Sweetie when I had just extolled her responsible nature eluded me. Perhaps it simply stemmed from my desire to protect her.

They both heard the sickening noise of the metal club hitting her left side. The turtle watched in horror as the girl let out something between a gasp and a cry, and landed, hard, in a puddle a few feet away.
“Spider-Ninja? Wait, you’re a kid?” Hockey Mask Guy muttered, sounding horrified as he looked at the injured teen.
Raph didn’t bother to respond. At that moment, he snapped. All he saw was red.
“DON’T TOUCH MY SISTER!” He roared before reverse punching the guy in the face, cracking the hockey mask. He ripped the guy's weapons from his hands, then ripped off the sports bag and threw it aside. Then he physically picked up Hockey Mask Guy and threw him.

Scumbag is still grinning. That's just... fucking creepy. It'd be creepy on a good day, but now he's in Fuyumi's body, and oh god, this is why he [Dabi] doesn't talk to any of his siblings anymore: when anyone at all fucks with them, he gets the absolutely irresistible urge to throw down, and that didn't pan out so well against Endeavor.

Akaoni: (steals Yui) Come on, you dumb Cure! Fight me!
Nao: Uh? (jumps out) You put her down right now!

"Listen, I know EXACTLY who you are. Hans Grubhund wanted for terrorism, smuggling, extortion among other crimes. Now I don’t know what you’re looking to get out of this. But you made a very, VERY, big mistake; do you want to know what that mistake is? You thought that you could pull this stunt in MY, city, while Judy Hopps is on the job. What’s more, you dragged family into this. Not my entire family obviously, but my brother means the world to me. So go ahead, send every wolf you brought with you after me and my partner. All they’ll do is delay us, and I promise you. Even if you somehow escape me tonight, I’ll look for you… I will find you… and I will kill you. So the real question is this Mr. Grubhund, are we going to do this the easy way? Or are we going to have to do this the hard way?"
Judy Hopps, Zootopia Files

Films — Animation

Spike: Good luck running a business with this idiot. (throws a used crumpled napkin at Luigi)
Mario: (catches it before it hits Luigi in the face) Say that again about my brother, and you're gonna regret it.
(Mario throws the napkin back at Spike's face)

Scowler: (as Gorgon is mauling him) Patchi! Don't just stand there! Get out of here! Run!
Patchi: But you're my brother! We have to stick together!
Scowler: I meant run away!
Patchi: I know what you meant!
Scowler: Go on! Don't worry! I'm wearing him out!
Patchi: I'm not going anywhere!
Scowler: Patchi, save the herd! Lead them to safety! You don't owe me anything, little bro! Don't be a hero!

Films — Live-Action

"You know there was a time when I wanted to meet you more than anything. Get to know my little brother. Let him know that he wasn't alone, that we were in it together. If only I had known what a dick he would turn out to be."
Arthur Curry to Orm, Aquaman (2018)

O'Leary: We heard about your brother's death. The last thing we need is you running through the streets creating a river of blood.
Black Dynamite: Tell me who did it and I'll just leave a puddle.

"You touch my sister again, I'll kill you."
Sonny Corleone, The Godfather

"Just so we clear...if you ever hurt my sister, in any way, make her cry, make her sad, just once...I'm coming at you with razor blades and lemon juice. I'm talking pain, boy. Searing, mind-numbing pain. Welcome to the family."
Big Black Jack, Norbit

"You take care of me. You've always taken care of me. My turn."
River Tam, Serenity

Literature

<Not Jake. Leave Jake alone. Leave my brother alone. I'll... look, I'll never trouble you again. I swear it. Just leave Jake alone.>
Tomnote , Animorphs #6: The Capture

Live-Action TV

"My sister, my responsibility."
Bellamy's motto, The 100

Dallas: Who knew your little sister was cooler than you.
Drew: Adam's a boy. Make fun again and I'll make your life hell.

“Ted, you do realize that by the unofficial code of big brothers, I should expose you and your friends vital organs to daylight.”
Eddie Winslow, Family Matters

"Johnny was always the one in the family we knew was going someplace. Sweet kid, smart kid. Becoming a doctor? This is all he ever wanted, and yet, somehow, you've found a way to beat that out of him, haven't you? Turn him into some kinda cynical guy who seems to despise what he does. Dr. Cox, Johnny is never gonna look up to me. Ever. But he hangs on your every word. So I'm askin'— (rethinks) I'm tellin' you: take that responsibility seriously, stop being such a hardass. Otherwise you're gonna have to answer to me."
Dan, Scrubs, "My Brother, Where Art Thou?"

John Winchester: All right, if I'm not back Sunday night?
Young Dean: Call Pastor Jim.
John Winchester: Lock the doors and windows, close the shades, and most important...
Young Dean: Watch out for Sammy.

Michael: You said you're a big brother.
Dean: Yeah.
Michael: You take care of your little brother? You'd do... anything for him?
Dean: [heartfelt] Yeah, I would.

Michael: My brother's sick.
Dean: The little guy?
Michael: [nodding] Pneumonia. He's in the hospital. It's my fault.
Dean: Ah, c'mon, how?
Michael: I should've made sure the window was latched. He wouldn't have gotten pneumonia if the window was latched.
Dean: Listen to me. I can promise you, that this is not your fault. Okay?
Michael: It's my job to look after him.

"Get away from my brother. Before I tear your heart out."
Damon Salvatore, The Vampire Diaries

"Love, I will do breathwork with you later. I have to save you from a literal fucking serial killer first."
Forty Quinn, You (2018)

Video Games

"My brother is so attached to me! Can you believe it?"

Agent: [To the terrified librarian] Please come with us, Miss.
Librarian: [Shaking her head] No, no ! I have to stay. A place for every book, every book in its place.
Agent: We must insist that you come with us.
Neo: [Walking up behind the librarian] She said she doesn't want to go. Leave her alone.

Visual Novels

"You said an older brother protects his younger sister, right?... Yeah. I'm the older sister. So I have to protect my younger brother."
Illyasviel "Illya" von Einzbern, Fate/stay night

Web Animation

Don't worry, I've got you;
Nothing will ever harm you.
I'm close by, I'll stay here;
Through all things, I will be near.
— "Gold", RWBY

"You have ten seconds to take [those restraints off my sister] before I start hurting you."
Winter Schnee, RWBY

"You dared to make my baby sister hungry? You're going down jar!"

Webcomics

Indeed, this is the other "me," my younger sister Euryale. And if you lay a finger on her, I'll tear you limb from limb.
Stheno, Fate/Gamers Only

Web Original

"...if you ever hurt [Vivian], if you ever make her cry... I will find you. And then I will make sure that you find out why the first G in 'Grinning General' might as well stand for 'Gruesome'. Understood?"

Western Animation

Sokka: Katara, what's wrong?! (to Aang) What did you do?!
Aang: It was an accident! I was, uh... Katara, I'm so—
Sokka: (tackles Aang to the ground) I told you we shouldn't mess around with this! Look what you did! You burned my sister!

"It's one thing for Hiss to go against me. But when he moves against my sister, he's playing a whole different ballgame!"

Paige: Molly, a woman was really racist to Cole in the park earlier.
Molly: Are you serious? Totally unrelated, Dad, can I borrow the golf cart and something I can use for either slapping or poking?
Owen: I like you energy, but we're gonna handle it the right way.
Central Park, Season 3 "Lunar Palaver"

"Nobody steals from my big little sister!"
Chicken, Cow and Chicken, "Cow's A Beauty"

"Let go of me! He's weak, he'll get himself killed! DON!"
Hank Hall/Hawk, watching his brother Don/Dove risk his life to stop a killer robot, Justice League, "Hawk and Dove"

"Because you're my little brother, Goddamnit! And even when I'm fifty and you're forty-five, you're still gonna be my little brother!"
Kyle Broflovski, South Park

"Get away from my brother!"

Becky: Well isn't that nice? After stealing my diary, threatening to put it on the internet, and making me drive across the state three times, he needs my help? Give me one good reason why I should help him. Just one!
Mikey: Because he's your little brother, and he needs you.
Becky: (Beat) Please pull forward to the second drive through window.

"Don't hurt my bro!" (swipes the remote-controlled razor away, breaking it in the process) "Buzz off!"
Chris Kratt (who's ironically a younger brother), Wild Kratts, "Sloth Bear Suction"

Real Life

"I against my brothers, my brothers and I against my cousins, my family against the world."
Bedouin Proverb

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