Wakko:(holding up a vomit bag) Hey, mister. What's this? Bloski: A vomit bag. Wakko:(looks into the vomit bag) Oh, poo! I got gypped; there's none in here!
A character in Danger Mouse was named Prof. Squawkencluck despite being a mole. Averted in the 2015 reboot, where the character is now a chicken. The original Squawkencluck's name only made sense in his first appearance, where he did experiments on chickens.
The team reads the grave of Fry's brother, who seemingly stole Fry's identity after he was frozen and became the first man on Mars. The person in question was actually Fry's nephew, Phillip Fry II.
Leela: "Phillip Fry, the Original Martian." Fry: It's all lies, every word of it! He wasn't original, he wasn't a Martian, he wasn't Philip Fry, and since when is he a "The?" Bender: You're twice the "The" he ever was!
Stumpy from Kaeloo has hands and feet. The original concept had him have stumps instead of hands, but this was changed before the actual show was made. It's even more obvious in the original French version, where his name is Moignon, the French word for "stump" (of a limb).
In the later episode "Smooth Opera-tor", the opera that they're seeing focuses on two mob families named the Baritones and the Mezzo-Sopranos. However, as Milo points out, the Mezzo-Soprano parts are actually being performed by baritones.
In "Wilder West", they go to a dude ranch and Milo rides a horse named Psycho who, naturally, goes wild and tries to throw him off. When Zack asks if they can get him a calmer horse, the owner replies that Psycho is their calmest horse. "That's why we named him Psycho—on account of the irony."
"Party of Peril" features a character named One-Armed Willie, who notes that it's just a nickname, since he has both arms. And a peg-leg.
There is a place known as the Crystal Empire. It's actually a city-state within the kingdom of Equestria, whose head of state is a princess (albeit one implicitly lower ranked than the reigning Equestrian diarchy), rather than an empress. Back when it was actually independent, it was ruled by kings and queens rather than an emperor or empress.
Phineas: (After Candace and various others start falling from a plane) Wow, dumb luck. And over the Sea of Razor Sharp Rock Spires too! The Others: AAAAAAAAAAAAAAHHHHHHHH! Phineas: Good thing it was so inappropriately named! (Candace and the others land on ground made of pillows.)
Another episode has an over-caffeinated Dr. Doofenshmirtz naming his latest invention the "Luffaplux-Dil-Pickle-Inator". It makes things float.
The Quack Pack version of Duckburg, unlike the one seen in DuckTales (1987) and in the comics, is actually not populated by ducks (or any anthropomorphic animal), with the sole exceptions being Donald, Daisy, Professor von Drake, and the nephews.
Also, Duckworth (Scrooge McDuck's butler), despite his name, is actually a dog.
Rick and Morty: In "The Whirly Dirly Conspiracy", Summer accidentally turns herself into a giant when using Rick's growth ray to increase her breast size. Against Morty's advice, Beth attempts to fix the problem herself, but makes thing worse because the machine's settings are a case of this; when she sets it to "normal", Summer expands through the garage. When she sets it to "reverse", it turns Summer inside out.
She-Ra and the Princesses of Power: The "Rebellion" is actually an alliance made up of the various kingdoms fighting the Horde, meaning they are the legitimate government resisting an invading force. Sure, the Horde insists that the entire world is theirs by right, but the princesses also call themselves the Rebellion when they should really know better.
In "Lisa On Ice", during Lisa's nightmare about failing gym:
Judge: I sentence you to a lifetime of horror on Monster Island! (aside) Don't worry, it's just a name. [Cut to Monster Island; Lisa and others are chased by lookalikes ofMothra, Rodan and Gamera] Lisa: He said it was just a name! Man Running Beside Her: What he meant is that Monster Island is actually a peninsula!
Subverted in "'Scuse Me While I Miss The Sky", with the Deadly Meteor Shower; people are apprehensive about this name, until Lisa explains that it was named after its discoverer, Professor Artemis Deadly — who was killed in the shower of 1853.
And in "The Color Yellow", Bart learns that the Underground Railroad was neither underground nor a railroad, and wonders why they didn't call it "the Above-Ground Normal Road".
This exchange from the "Treehouse of Horror III" story "King Homer":
Carl: Hey, I hear we're going to Ape Island. Lenny: Yeah, to capture a giant ape. I wish we were going to Candy Apple Island. Charlie: Candy Apple Island? What do they got there? Carl: Apes, but they're not so big.
"22 Short Films About Springfield" actually has only 19 segments. Well, it would've been 20 if Professor Frink's segment hadn't been cut off by the end credits. Or, 17 segments if you counted Lisa's three-part story as one.
The Sonic Boom episode "The Sidekick" features Sonic going up against one of Eggman's robots, entitled "Burnbot". Said robot does not have any fire or chemical weapons, but claws instead. Sonic suggests using a name that isn't so misleading. Later in the episode, it is revealed that Eggman did take Sonic's advice by adding flamethrowers to Burnbot. Within the same episode, there's also the "incredibly dangerous, but inaccurately named" Mount Safety.
South Park has the song "Kyle's Mom Is A Stupid Bitch In D-Minor", which actually begins on a D-minor chord, but then immediately switches to a major key—nothing sung by Cartman is in a minor key. This might be a reference to "Singin' in the Rain in A-Flat" — which is actually in E-flat.
In the G1 episode "Enter the Nightbird", the character who needs help jumping up a cliff is the guy named Cliffjumper.
Bluestreak is silver, and not blue. Ironically, the Diaclone toy he was redecoed from was blue, and his packaging art showed him as being blue. Due to trademark problems, he was temporarily renamed "Silverstreak" in the 2000's, which fits better. But his thing is that he never shuts up; he talks a blue streak. "Silverstreak" just describes his color and implies that he's fast.
Transformers: Shattered Glass is a mirror universe story, where very few characters have changed names but nearly all have flipped personalities. This results in, among others, the dapper, cultured Abominus, the dashing, heroic Colonel Deathsaurus, Astrotrain, who doesn't turn into a train, Space Cowboy Bludgeon, and Whisper's No Indoor Voice. Sometimes, this gets a Hand Wave; Abominus named himself after a poem, and Whisper's name is apparently an Ironic Nickname.