- General Guerro, the Big Bad. His Establishing Character Moment is throwing one of his own men over a railing for failing him.
- Like the main series, the treasure of the Golden City carries a terrible curse, but unlike the main games, it's of a decidedly more grounded nature: the founders of the city had unknowingly built it inside a mountain full of uranium deposits. Not enough to kill fast, but enough that the people succumbed to a drawn out death from radiation poisoning over the course of decades, and the gold is saturated with centuries worth of radiation. It can never leave the mountain, because if the gold ever enters circulation, it'll be a death sentence to thousands of people
Nightmare Fuel / Uncharted: Golden Abyss