The Akatsuki organization from Naruto consist of shinobi from different villages in the ninja world. The members include Pain and Konan (Rain Village), Itachi Uchiha (Leaf Village), Kisame Hoshigaki (Mist Village), Sasori (Sand Village), Deidara (Stone Village), Hidan (Steam Village), Kakuzu (Waterfall Village), Tobi/Obito Uchiha (Leaf Village), and Zetsu (Unknown).
Cyborg 009 is one of the earliest pioneers of this, even preceeding X-Men of all things. 001 (infant Ivan Whiskey) is Russian, 002 (gang member Jet Link) is American (specifically, he's a New Yorker), 003 (ballerina Francois Arnoul) is French, 004 (East German escapee Albert Heinrich) is German, 005 (pacifist Geronimo Jr.) is a southwestern Native American, 006 (farm/chef Chang Changku) is Chinese, 007 (spy/actor Great Britain) is British, 008 (refugee/guerrilla fighter Pyunmar) is African (unspecified where), and 009 (Leader Joe Shimamura) is half Japanese, half American.
The Doraemon spinoff series, The Doraemons, revolves around the misadventures of the titular character (Japanese) and his fellow robot feline buddies, each of them a robot cat from a different country - Dora-the-kid from America, Doranichov from Russia, Doramed III from the Middle East, Dorawan from China, Dora-rinho from Spain and El Matadora from Spain. National stereotypes abound, too, with Dora-the-kid a cowboy, Dorawan a martial artist, El Matadora a bullfighter, Dora-rinho a soccer fanatic who's never seen without his football, and so on.
Sakura Wars's variousadaptations may take place mostly in Japan, but the Tokyo team alone has people from as far away as Italy and Russia.
Mithril from Full Metal Panic!! is this, with Sousuke being Japanese, Melissa a Chinese-American, Kurz a German, Teletha and Italian-American, and Kalinin being Russian.
Gundam usually has varied nationalities among its characters. Curiously, it's very rare for the main character to be Japanese (even partially); one exception is Domon Kasshu of G Gundam, and most protagonists in the Build series spinoffs.
Mobile Suit Gundam had Amuro (either Japanese-Canadian or Japanese-Mexican depending on version of the story), Bright (British), Ryu Jose (Argentinian), Kai Shiden (Puerto Rican), Frau Bow (German), Mirai Yashima and Hayato Kobayashi (both Japanese), as well as a number of Space Colonists such as Sayla Mass (supposedly of French descent).
Victory Gundam had a unusually (at the time of the series) high variety of races amongst the recurring cast. The main character, Usso, is European, but Shakti, the female lead, is of African or Indian descent, as are a large number of side characters.
In G Gundam, a unit of True Companions was formed from rival champions of different countries: American Chibodee Crockett, French George DeSand, Japanese Domon Kasshu, Chinese Sai Saici, and Russian Argo Gulskii. There were also recurring heroic characters Swedish Allenby Beardsley and German Schwarz Bruder.
Mobile Suit Gundam Wing's True Companions were Japanese (Heero), United States (Duo), European (Trowa), Arabian (Quatre), and Chinese (Wufei) descendants, though the important nationality distinction for them was that they were all Colonists and not Earthlings.
In Planetes, the Technora Corporation Debris Section has two Japanese astro-trash collectors, a Cuban-American captain, a Russian first-mate, a caucasian (probably American, but at the same time fulfilling Japanese middle manager stereotypes, and relatively harmless) Pointy-Haired Boss, his boot-licking toady from India, and a German Office Lady temp.
In the anime. In the original manga Fee is clearly black and the office staff don't exist.
Planetes also feature at least two mixed marriages: Fee's stay-at-home hubby is white, while Yuri's late wife was Japanese.
In Kagaku Kyujotai Technovoyager, the team consists of a Japanese (who is the central character in the series), an American, an English, a Jamaican and a French. However, the characters' nationalities were changed into American when the series was exported to the US as Thunderbirds 2086.
Black Lagoon — kind of. Revy is a racially Chinese American, Dutch is black American, Benny is Jewish American and Rock is Japanese... Not-american. Defining them as 'good guys' is kind of a stretch too. Since they're pirates, Equal-Opportunity Evil may cover them just as well.
If you expand the scope a little to include some of the people they have happened to have teamed up with on occasion, the list includes the Russian Balalaika, Taiwanese Shenhua and her Irish driver, and the presumably Hong Kong Chinese Mr. Chang.
Kirika is Japanese, or at least asian, while Mirielle is Corsican French, in Noir.
Each Macross series generally features a cast of various ethnicities and nationalities. After being Macekred into Robotech, Super Dimension Fortress Macross purportedly showed one of the first romances between a Caucasian and African on US animation.
In the Space Western-cum-Humongous Mecha anime Sei Juushi Bismarck, the main team of heroes consisted of an Englishman, a Japanese, an American and a Frenchwoman; each one wore the appropriate flag on his/her battle helmet and uniform. When the show was Americanized as Saber Rider and the Star Sheriffs, the Japanese and French characters' nationalities were ignored. However, since the show was a Space Western and the American character was a futuristic cowboy, he got to stay American. The Englishman also retained his nationality; in fact, the plot of one of the new episodes made for America was based on his status as a descendant of Scottish royalty.
D.Gray-Manloves this trope. Allen is British, Lenalee is Chinese, Kanda is Japanese, Krory is Romanian, and Miranda is German. It's the same with the bad guys; Tyki is Portuguese, Lulu Bell is French, and Skinn, Jasdero, and Devit are American. Listing all the examples this series has would take too long. Kanda's nationality has never been confirmed, and is always given as 'Japanese?' with a question mark. Recent plot developments suggest he is more likely to have been born and raised in China.
The titular organization in Strike Witches is one of these, with members from their world's Fantasy Counterpart Cultures of Japan, Germany, England, Russia, France, Italy, Finland, and the United States.
Transformers: Super-God Masterforce: Shuta and Ginrai are Japanese, Cab is Filipino, Minerva is French, Lightfoot is American, Ranger is Canadian, and Road King is British.
Even the bad guys get in on the action — Cancer is Chinese, Bullhorn is Mexican, Wilder is American, and Hydra and Buster are (East) German. The rest of the Decepticon-allied humans in the series - Clouder, Giga, and Mega - are of unspecified nationality.
The mercenary pilots of Area 88 primarily come from the NATO powers: Americans, West Germans, Brits, and others. The main character is Japanese.
Don't forget the BBA! Bakuten Shoot Beyblade's main protagonists were Takao (Japanese, and the leader), Rei (Chinese), Max (Japanese-American), and Kai (Japanese with cultural ties to Russia). They got to compete against plenty of other teams, some uninational and some also multinational.
Hetalia: Axis Powers of course, being that the characters are personifications of nations as well as acting as a soldier from each. The main two groups would be the Axis Powers and Allied Forces, though the idea of good guys and bad guys is not the point of the series. The main character is North Italy, though Germany seems more in charge. The United States usually acts like the head of the Allies, much to the chagrin of England.
From The Legend of Koizumi, when time comes to save the world from Space Nazis, we get the main team of Junichiro Koizumi (Japan), Vladimir Putin (Russia), Pope Benedict XVI (The Vatican), George H.W. Bush (U.S.A.) and Yulia Tymoshenko (Ukraine).
The Mighty Bombshells, a failed attempt to bring the American style of comic book art to manga, consisted of Ms. Liberty and Dynamite Girl (U.S.A.), Fireball (England), Blitzkrieg (Germany), Red Dragon (China), and Cherry Blossom (Japan).
Infinite Stratos has more of a Multinational Battle Harem which, according to Maya, is actually "enough to start a war": Ichika and Houki are Japanese, Cecilia is British, Rin is Chinese, Charlotte is French, and Laura is German. Season 2 then throws in the Half-Russian, Half-Japanese Sarashiki sisters in the mix.
Shaman King does this with some of the teams. But since there are really only four factions in the shaman fights, it's natural.
The Idol Choujin in Kinnikuman include, by the end of the series: Kinnikuman and Rikishiman/Wolfman (Japanese, although technically Kinnikuman is an alien), Terryman, Specialman, and Geronimo (American; Geronimo is a full-blooded Apache), Robin Mask and Neptuneman (British), Warsman (Russian), Ramenman (Chinese), Buffaloman (Spanish), Brocken, Jr. (German), and Canadianman (Guess, dummy.)
Sequel series Ultimate Muscle features the New Generation Idol Choujin: Kinniku Mantaro/Kid Muscle (from Planet Kinniku), Terry the Kid/Terry "The Grand" Kenyon (Japanese-American), Kevin Mask (British) Seiuchin/Wally Tusket (Irish), Gazelleman/Dik Dik van Dik (Tanzanian), Checkmate (from Monaco), Illoukhine/Comrade Turbinski (Russian), Jade/Jaeger (German), Scarface/Eskara (Italian), Barrier-Free Man (Swedish), Chaos Avenir (alien from an unknown planet), and Hanzou/Hanzo the Horrible (alien from the planet Iga)
There's also virtually every villain group from either series, but we'll spare you the details.
Gravion Zwei featured the Gran Troopers — Faye (Chinese), Alex (American), Hans (German), Ivan (Russian), and Jose (Brazilian).
Silent Möbius has the AMP team, Kiddy Phenil (Australian), Lebia Maverick (American), Katsumi Liqueur (half-Japanese, grew up in Hawaii), Lum Cheng (Chinese), and Rally Cheyenne (half-human, mother's nationality unknown). Yuki Saiko, Nami Yamigumo, and Mana Isozaki are Japanese.
The superheroes of HeroTV in Tiger & Bunny come from a variety of backgrounds, despite not being an actual team. Kotetsu/Wild Tiger is Japanese. Antonio/Rock Bison is Hispanic or possibly Mexican descent. Ivan/Origami Cyclone is Russian. Pao Lin/Dragon Kid is Chinese. Keith/Sky High is American.
Code Geass has this somewhat with The Black Knights. As they are a Japanese resistance group, the vast majority of its members are, obviously, Japanese. However, its core members include Britannians (Lelouch/Zero, Diethard), Indians (Rakshata), and later, Chinese (Xingke, Tianzi). It's explicitly stated that they are fighting for justice and to rebuild the nation in a new vision as the "United States of Japan". Your ethnic background is of little importance.
Jewelpet Twinkle☆ has the Magic Academy's students. The protagonist Akari is Japanese, Sara is half-Japanese, half-Indian, Miria is from the USA, Leon is Austrian and Nicola is Russian.
A variant of this trope is present with the Ooarai Girls' Academy sensha-do club of Girls und Panzer. While the members of the club are Japanese, their tanks are from units from different countries: Germany (Panzer IV, StuG III, Tiger(P)), France (Char B1 Bis), USA (M3 Lee), Czech Republic (Panzer 38(t)), and Japanese (Type 89, Type 3 Chi-Nu). Justified as these tanks are the remnants of the then defunct sensha-do club of Ooarai, and the better tanks were sold off in the past.
Little Witch Academia takes place at a British Wizarding School with a lot of international students. The main trio consists of Atsuko "Akko" Kagari (from Japan), Lotte Yanson (from Finland), and Sucy Manbavaran (from the Philippines). Other prominent characters include Diana Cavendish (from England), Amanda O'Neill (from the USA), Constanze Amalie von Braunschbank-Albrechtsburger (from Germany), and Jasminka Antonenko (from Russia).
Great Pretender: Laurent's crew hail from Japan, France (...as far as most people knownote he's actually Belgian), Iraq, South Korea, and potentially the United States, given Cynthia's accent.
Dr. STONE: The astronauts on the ISS include three Russians, one Japanese, one Asian-American, and one White American (technically a space tourist).
Yakitori: Soldiers of Misfortune: The protagonists Unit K-321 is made up of Akira Ihotsu (Japan), Tyron Baxter (USA), Amalia Schulz (UK), Zihan Yang (China) and Erland Martonen (Sweden).
