While seniors are usually exempt from harm due to harming the elderly being a taboo, there are exceptions. A villain hurting a senior is practically guaranteed to be a Kick the Dog moment at minimum. Whether a hero hits a villainous senior depends on how healthy they are, how dangerous their scheme is, and the hero's morality. An elderly villain who's clearly in good shape is more likely to get attacked by a hero, a villain that plans on killing someone is also likely to get hit if there are no other options, and an Anti-Hero might not care at all if they're violent enough.
- The Seven Deadly Sins: Played for Laughs. During the Vaizel Fighting Destival, King is paired off against an unassuming old guy, and is eager to beat him in order to impress Diane. Alas, King is so ineffective in a fight when unarmed that the old guy, who it turns out is a capable fighter, wipes the floor with him.
- Watchmen: Thugs break into retired superhero Hollis Mason's home and assault him. He is beaten to death with a statue he had received as an award for his heroism.
- Judge Dredd: In a short comic, Judge Death tried to use a teleporter to escape imprisonment in Mega-City One, but somehow wound up at a senior citizens gathering in the late 20th century UK. He proceeded to grant everyone an early ticket to the grave before Dredd showed up to recapture him and take him back.
- In Atlantis: The Lost Empire Rourke punches the King of Atlantis, who's thousands of years old, in the stomach, causing him to die of internal bleeding.
- The Emperor's New Groove: When Kuzco accidentally bumps into an old man unfortunate enough to be standing nearby during his opening song, Kuzco has the old man thrown out the window. Fortunately, the old man ends up comically wrapped up in some banners and unharmed, and this is just meant to show that Kuzco is a Jerkass, although he gets better.
- In Madagascar: Escape 2 Africa, Alex the lion is more than willing to get in a one-on-one combat with the little old lady who beat him up in the first film. Despite Alex being a fully grown male lion, the old lady still wins the fight.
- In The Secret of NIMH, Jenner has no qualms about killing an ailing Nicodemus, and viciously shoves aside a crippled Mr. Ages to pursue Mrs. Brisby.
- In The Avengers, when one old man (who is implied to have lived through Hitler's regime and felt quite indignant about the Nazis) refuses to bow down to Loki, Loki is about to kill him before Captain America stops him.
- The Bad Lieutenant: Port of Call New Orleans: Lieutenant McDonagh (our hero, folks) assaults an old woman by withholding her oxygen supply since he needs some information from her friend. They file a report against him, but he gets away with it in the end.
- Logan: Wolverine's clone X-24 is perfectly willing to stab the nonagenarian Professor X in the chest. Xavier doesn't survive.
- Played for Laughs in Madea's Family Reunion when Keke Palmer's character takes off her earrings in an attempt to fight Madea, but she gets beat by Madea instead.
- In Madea Goes to Jail, the police had no problem attacking Madea to arrest her.
- In Blazing Saddles, Rock Ridge goes from being a humble little western Arcadia to a Wretched Hive, this cemented by a pair of thugs brutally beating on a defenseless old lady.
Old Lady: Have you ever seen such cruelty?
- In The Toxic Avenger, the titular monster hero goes on a murder spree towards every thug, rapist, pedophile and bank-robber in Tromaville and quickly becomes beloved by the people for it (it's a Troma film, so over-the-top violence and murder is the norm). When he is found dry-cleaning a seemingly defenseless old lady, the corrupt mayor uses this as an excuse to send the army and his corrupt, Nazi police commissioner after him, leaving out the fact that the old lady was a sex-trafficker with a criminal record a mile long.
- Rampage (2009): Subverted during Bill's rampage. He goes into a bingo hall filled with senior citizens, walks menacingly around them as none of them seem to notice the armored gunman... and then he walks back out, reasoning that they're gonna die pretty soon anyway.
- Circle: As soon as people realize that the order of killing is based on voting, College Guy suggests killing off the oldest people first in order to buy themselves more time because it's "more fair", which the room begrudgingly agrees to. However, when they run out of truly elderly people, the room turns against him because it's clear he's just going to keep targeting people based on age.
- Villains in Warrior Cats occasionally attack elders; one example is in the first book when ShadowClan attacks ThunderClan and Blackfoot kills the elder Rosetail as she defends the nursery.
- Also in the first book, Brokenstar exiles all of the elders because he thinks they are too weak and a drain on the Clan's resources.
- Walker, Texas Ranger: C.D. Parker, a retired Ranger, is often targeted by the villains in a way to try to intimidate Walker. This tactic, of course, only makes Walker madder.
- New Jack bolstered his already infamous reputation when he beat Garbage Wrestler pioneer Gypsy Joe with a baseball bat.
- Randy Orton's "Legend Killer" gimmick sounded badass, until you realized to him "killing legends" mostly consisted of disrespecting and beating up retirees, included women less than half his size. Only occasionally would Orton have a match with someone still capable of having matches.
- Kane's feud with Shane McMahon was kicked off by Kane dropping the head of Shane's mother on a steel ramp, describing the sounds the damage it did to her body made and how causing pain turned him on.
- Kevin Steen's ultimate goal in Ring of Honor, while leading SCUM anyway, was to kill Carry Silkin with his bare hands as his final act in symbolically destroying the company. Silkin was of course old and not a wrestler.
- In Infamous Second Son, the Big Bad Brooke Augustine is convinced that Hank - one of the conduits, or "Bio-Terrorists" as she insists they be called, escaped their custody - might have told something incriminating to Delsin or one of the Akomish while he was in their longhouse. Regardless of whether Delsin tells Augustine that he is a conduit or if he lets her move on to the others, she will proceed to use her concrete powers to "interrogate" the rest of the tribe, starting with the elderly Betty.
Augustine: Well, unless you decide that you do have something to tell me, I'll go 'chat' with that old lady. But you should know, concrete is especially hard on brittle bones.
- Played for Laughs in Cthulhu Saves the World bonus campaign "Cthulhu's Angels", where Dark Umi, evil personality of Umi, expresses delight when she gets to destroy the game's Interactive Narrator, who is an elderly man. Mitigated only by the fact that he's a Reality Warper and a Physical God.
- Strong Bad from Homestar Runner is a jerk to everyone, including the elderly King of Town. Some of the things Strong Bad did to the King of Town include hitting him in the face with a scepter, sending him off a cliff (with some snacks), ripping off chunks of his beard, and lowering him into a cauldron of boiling butter, although the King of Town didn't mind that last one.
- Discussed, exploited, and ultimately subverted in Digger with Boneclaw Mother, a Cool Old Lady who doesn't let age and blindness stop her from dispensing threats of violence against those who would harm her tribe. As she says, if someone were actually to agree to fight her, then they'd either get beaten up by an old blind lady or become known as the Jerkass who beat up an old blind lady. As a shaming tactic, it even works on a Knight Templar with urgent personal reasons to fight past her.
- In the The Powerpuff Girls episode, "Fallen Arches", the Ministry of Pain come out of retirement after several decades to commit crimes. Even though Bubbles and Buttercup are more than willing to stop them, Blossom refuses to let them because they have to respect their elders. The Powerpuff Girls get around this by enlisting Captain Righteous and Lefty, two equally-elderly former superheroes, to fight the Ministry of Pain.
- Eustace and Muriel in Courage the Cowardly Dog are frequent victims of this. Each Monster of the Week capture them and/or attempt to harm them in any way they possibly can without a single qualm of their actions regardless of their old age. Of course, unlike Muriel, Eustace often deserves whatever horrible fate he receives since half of the Bagges' ordeals are due to his stupidity and stubbornness getting them in the mess, which is also helped by his immaturity despite his old age.
- The villains from Jackie Chan Adventures have no problem attacking Uncle. With him being an Old Master chi wizard, he can triumph over them.
- In the Avatar: The Last Airbender episode "Jet", the gaang meet with Jet and his Freedom Fighters. While Sokka does not trust any of them from the get go, his distrust is cemented when he joins their patrol and finds Jet needlessly threatening an elderly traveler. When Sokka goes to tell Katara and Aang about it, Jet claims that the old man was a Fire Nation assassin sent to kill him and shows him a poison-laced dagger that he claims to have frisked off of the old man. Since neither Sokka, nor the audience ever see this knife on the old man's person, this is likely to be a lie.