Shades of Grey may refer to:
- Shades of Grey, a science fiction novel series by Jasper Fforde.
- Shades of Grey, an manga and anime blog.
- Shades Of Gray (2002), a fantasy webcomic about Heaven and Hell. Includes mild(ish) nudity.
- Shades Of Gray (2006), a science fiction web comic. Part of several webcomics set in the same universe.
- Fifty Shades of Grey, an erotic novel by E.L. James.
- Grey and Gray Morality, a trope about the nature of all things being varying shades of morally ambiguous.