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"Every part of the Kaiju sells. Cartilage, spleen, liver... Even the crap! One cubic meter of crap has enough phosphorus in it to fertilize a whole field!"
Hannibal Chau, Pacific Rim
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Where most people see danger in monstrous creatures, some see dollar signs. When a monster is the source of a substance (often a drug) that can be sold for massive profits, or bartered for power over others, then people looking to cash in on its byproducts may prove more dangerous than the creature itself. If the source-creature is non-sentient, expect it to be kept captive as a resource, until it escapes and goes on a rampage. If it's intelligent, expect it to bind hordes of Mooks to its service with its "gifts", to say nothing of people in positions of political influence... or to be kept captive as a resource anyway. Either way, expect those who crave its byproducts to stand between it and any pesky do-gooder monster hunters who might cut off their supply.

Compare Milking the Monster, where it's the very presence of the monster that works to someone's financial or social/political advantage. Cases where the monster is self-aware and its "gifts" are plot-enabling are Sentient Phlebotinum; those in which the monster is portrayed sympathetically, suffering in its captivity, overlap with Powered by a Forsaken Child. Sometimes overlaps with Fantastic Medicinal Bodily Product if the substance has healing properties. The Power of Blood might be the desirable part. If it's specifically the monster's waste that's the desired substance it's Solid Gold Poop.

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Examples:

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    Anime & Manga 
  • Bio-Meat: Nectar: If they weren't a massively profitable source of marketable food for humans, the B-Ms would've surely been written off as a bad design and destroyed as soon as their appetite for people was noticed. Instead, the Corrupt Corporate Executive whose company created them writes off one catastrophic BM escape after another, and is perfectly content to slaughter innocents and his own son to protect his "product"'s public image.
  • Cross Ange: One interpretation of what Embryo does to Aura to collect "Mana" for his utiopian ideal society is this.
  • In Drifters, the Bronze Dragon tries to cop an attitude with the Ends' Black King. Irritated, the King uses his powers over life to fill the Dragon to bursting with it... in the form of cancer boils. The thing is, those boils are made of the same bronze metal of the Dragon's skin, so the Ends' army simply nailed the Dragon to the ground and began tearing them off as a cheap and easy source of metal for their weapons and currency.
  • Similar to whaling in the real world, Drifting Dragons has dragons hunted for their oil which is used as fuel and their delicious meat.
  • Gintama: One episode is about a rural village that is plagued by hordes of monsters... RPG monsters. The town quickly learns the definition of lootsplosion and bullies away all the mercenaries that they were desperately calling for earlier. Unfortunately for them and the main characters, the gold mine runs out when they kill the final boss and the beasts' creator thanks them for their greed, leaving. The main characters discuss this and then go back to fighting over 100 yen on the ground.
  • Neon Genesis Evangelion: For the pilots to power the giant EVA robots it's essential that they establish a good sync with the robot, and for this purpose they are immersed in LCL - a breathable fluid that greatly eases the sync process. It turns out that LCL is the blood of the second angel Lilith, kept crucified deep underground, wounded and constantly bleeding into a vast lake.
  • Puella Magi Madoka Magica: The Grief Seeds dropped by witches when they are killed are given to Kyubey for him to use to stave off the heat death of the universe. It’s too bad that the witches were once magical girls that were intentionally corrupted by Kyubey for this exact purpose.
  • Silent Möbius: One chapter centers on the drug "Domel", a performance enhancer that has the unfortunate side effect of mutating users into monsters and then melting down when their bodies are no longer able to withstand the changes. It's extracted from a captive Lucifer Hawk, an interdimensional demon.
  • I Couldn't Become a Hero, So I Reluctantly Decided to Get a Job: Amanda, the rival company to the magic item store that the protagonists work for, is able to undercut its competition by building all its magitech appliances by working peaceful monsters to death as slave labor.

    Comic Books 
  • Alien: Aliens produce Royal Jelly, which has the same role for this species as it has for real-life bees. However, it is also an extremely valuable substance in human society, used as a powerful and mind-enhancing drug for wealthy individuals. Since the only source of Royal Jelly is often deep inside an alien hive, collecting it can be very dangerous. The Hive mini-series details such an operation.
  • Empire: Inverted, as the tyrannical Golgotha keeps his inner circle in line by feeding them an addictive substance known as "eucharist," which is made from the blood of the imprisoned superhero Endymion.
  • In L Imploseur, a French comic, the miracle drink Ultra which boosts reflexes, muscles, etc. turns out to be the blood of a goat-human hybrid.
  • Marvel Comics:
    • Daredevil: Mutant Growth Hormone was a popular drug, and still resurfaces from time to time despite Daredevil's best efforts.
    • Ultimate X-Men: The original run has Banshee, a performance-enhancing drug for mutants that significantly increases their powers, which was created from Wolverine's blood.
    • War of the Realms: Laufey's forces capture the primordial giant Ymir and use human slave labor to chip off chunks of him that spawn new ice giants to bolster his armies.
  • The Real Ghostbusters: In the Slimer! series, a pair of unscrupulous, down-on-their-luck mechanics attempt to capture Slimer and bottle his slime upon discovering that the stuff can keep a car's radiator from overheating no matter what.
  • The Smurfs: One of the reasons Gargamel goes after the Smurfs is because they are an ingredient in a formula for the Philosopher's Stone.
  • Transmetropolitan: One character injects molecularly replicated Hitler pee.
  • In Operación Bolívar, a Mexican graphic novel, the protagonist is a dedicated angel hunter, who basically butchers angels to sell their immensely profitable body parts - everything from an angel's corpse has extremely valuable properties, from the hair to the blood. Part of the story's conflict starts when the threat of dragon scales begins creeping from Asia, and the attempted response is a plan to turn angels into a massively farmed species.

    Fan Works 
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    Films — Animation 
  • Princess Mononoke: The Forest Spirit has power over life and death, and his blood is believed to grant immortality, which is why the Emperor of Japan has placed a bounty on it. When the Forest Spirit is decapitated during his Night Walker transformation, his blood turns into a World-Wrecking Wave that sucks the life out of any living thing it comes in contact with. After his head is returned, his blood turns into a World-Healing Wave, kick-starting a new forest as well as healing the lepers and Ashitaka's curse.

    Films — Live-Action 
  • The Field Guide to Evil: In "What Ever Happened to Panagas the Pagan?", the goblin bleeds an incredibly intoxicating wine that, according to legend, can send the drinker mad.
  • Godzilla:
    • Godzilla: King of the Monsters (2019): Briefly mentioned, although it might be further explored in a future MonsterVerse installment. According to Dr. Graham, there's a new and dangerous market in trafficking Titans' DNA which Alan Jonah is invested in.
    • Shin Godzilla: The Americans discovered Godzilla long before he hit land, but kept this secret so as to be the first to benefit from researching its Bizarre Alien Biology (including a new element formed inside its body). As Godzilla is left frozen but intact, many are hoping such discoveries could help fund the reconstruction of Tokyo.
  • In Jason X, someone who got the bright idea to try to experiment on Jason to see if his unkillability can be replicated kicks off the next killing spree.
  • In Pacific Rim, there's a lucrative black market selling body parts harvested from dead kaiju, and Hannibal Chau is its king. Aside from the kaiju brains (which have too much ammonia), every part of the kaiju is useful (or at least, Chau has convinced his customer base of this fact), even their feces and skin parasites. Thankfully the black market dealers are smart enough to wait until the PPDC does their job and renders the kaiju dead before moving in to make their money.
  • Pete's Dragon (1977): Doctor Terminus wants to get his hands on Elliot (the titular dragon) to make him into medicines.
  • In Spiders 3D, the giant spider-alien hybrids were being bred in captivity because their silk would have industrial and military applications.
  • The Stone Tape: Brock's first thought upon realizing that the "ghost" is more of a recording than an entity is to redirect the think tank's resources entirely to commercializing an information-storage system based on the same principles.

    Literature 
  • Alastair Reynolds:
    • In Terminal World, the world has been divided up into differing areas of technology, where the laws of reality are literally different from one are to the next, limiting how advanced certain items can be in certain areas. For the people of this world, traveling between these areas involves suffering from the debilitating "Zone Sickness" that, in severe enough cases (or too fast of a transition between different zones) can kill. Fortunately, creatures called Carnivorgs can synthesize a medicine that alleviates the sickness... unfortunately, as their name would suggest, the Carnivorgs are vicious carnivorous cyborgs who harvest the brain matter from the people they capture.
    • Revelation Space Series: In Chasm City, an alien marooned on Yellowstone is the only source of a drug that can suppress the melding plague.
  • In Alien in a Small Town, kreg is a live alien virus. The human body can fight off the infection, but the user experiences a hallucinogenic high until it does; and the user's body does not gain a lasting immunity, so subsequent use will give a longer and longer high until the user may eventually be trapped in a hallucinogenic state lasting for days.
  • Animorphs: The Venber are a sentient race with unusual physical properties, chief among them that if they are brought to a temperature above freezing, they melt. The resulting liquid is apparently an excellent coolant fluid for supercomputers, and the Venber were hunted to extinction by "The Five" for it.
  • And Then There Were Monsters: This is the only way the people of Grandsbriar have survived so long. In addition to collecting parts from monsters they kill for potions and weapons, they've also started trying to domesticate some of the less hostile types, like leaf dancers. It's slow going, because most of the monsters don't reproduce too close to human habitation.
  • Anno Dracula: In "Andy Warhol's Dracula", the central character is a drug dealer whose product uses vampire blood as its key ingredient.
  • In Coldfire Trilogy, the Forest is a very dangerous place since it's the Hunter's domain. People live near it and venture into it anyway because the Forest, due to the Hunter altering its ecosystem for centuries to suit him, is also home to unique flora and fauna that don't exist anywhere else. For example, there's a breed of wolf that only lives in the Forest with pelts so beautiful that people will pay a small fortune for them. One can make a good living gathering and hunting in the Forest as long as one pays the Hunter due respect.
  • The Dark Profit Saga: One magical weapons manufacturer tempers their swords in the blood of a fire drake, which is kept chained up and constantly bled slowly in their factory.
  • The Day of the Triffids: Triffids are initially culled because their predatory habits pose a threat to humans, but when it turns out they can be exploited as a source of a high quality oil, they are captured, have their stingers removed, and farmed instead.
  • The Dresden Files: The Red Court's saliva is addictive and a fairly powerful narcotic, and the vampires use this to hold onto political power in Latin America.
  • Dune's sandworms are the source of the invaluable Spice, without which galactic civilization would collapse. While keeping them captive is unfeasible to say the least, the need to preserve their species runs at odds with the Fremen drive to make Arrakis more livable for humans (due to water, a necessary component of any reasonably human-inhabitable environment, being lethal to the worms), making it a major political issue.
  • In The Golgotha Series, Clay begins keeping some of the worm-like Tainted parasites birthed by the Mother of a Thousand Young in captivity so he can harvest their secretions as ingredients for a regenerative serum.
  • Mercy Thompson: Vampire blood as a restorative.
  • In Perdido Street Station, the slake-moths are a source for the highly addictive drug called dreamshit, and were being milked of this substance before their escape.
  • The Relic: At the end of the book, the monster-creating reovirus is used by one of the survivors to concoct a new street drug, Glaze. It turns out to have some nasty side effects in the sequel, and its derivatives are even worse.
  • In Relics, by Tim Lebbon, the protagonists fall afoul of black marketeers who covertly trade in fantastical creatures' body parts and discover that such creatures are so rare they're considered mythical because humans have been butchering them for their body parts for thousands of years.
  • Repairman Jack: In All the Rage, blood from Scar-lip the rakosh is the sole source of the Psycho Serum Berzerk.
  • In The Shattered World, by Michael Reaves, dragons are hunted through the Abyss between fragments by "dragoneers", who harvest their hide, flesh, bones and oil. This is dangerous yet profitable, as only dragon-derived materials can be enchanted to stay on course and maintain Artificial Gravity within the Abyss, so there's no other way to build flying ships.
  • A Simple Survey: One story revolves around this. The narrator is a professor who specializes in researching monsters that become pests to human society. By finding ways to profit off them, he can create an incentive for peasants to hunt the monsters and keep their populations in check. In the story, he and his assistant dissect a troll and discover uses for its stomach acid and liver. But releasing this information doesn't have the intended effect. The peasants, instead of killing the trolls, gather the materials non-lethally (by forcing the trolls to vomit out acid, and cutting away pieces of the liver at a time). On top of that, they've even started setting out food for the trolls, increasing their population.
  • In the firefighters-vs-dragons novel Smoke Eaters, a derivative of dragon blood proves to have remarkable healing properties, and to immunize humans who receive it via transfusion against the choking effects of dragon smoke. Once this is demonstrated, the titular anti-dragon crews shift tactics from exterminating the ferocious beasts to capturing them alive as blood donors.
  • Sonja Blue: Inverted — or maybe not — in one of the novels, in which demons use the corpses of especially-evil humans as hard drugs. One demon gets bribed with some of Hitler's teeth.
  • The Sookie Stackhouse Mysteries, and the TV series based on them, have vampire blood as a hot commodity. It's essentially treated like a very addictive drug.
  • Star Wars Legends: One novel has a spider monster that produced a spice called glitterstim, which needs to be harvested in complete darkness. The spider uses it to make its webs, while other creatures use it for some kind of mind reading (and also just to get high).
  • The Stormlight Archive: The chamsfiends (essentially carnivorous lobsters the size of skyscrapers) have a massive gemheart, which is even more valuable because gems are the only way of storing the titular Mana. While hunting adult chasmfiends is quite dangerous, they have a pupal stage in their life cycle, during which they are briefly helpless.
  • In Updraft, skymouths (invisible flying tentacled maws) are highly dangerous, but also provide useful materials; in particular, sinew which allows the construction of bridges between the towers which constitute the city. Singers, who are responsible for protecting the city, maintain some of their clout thanks to the prosperity this sinew brings them. It's eventually revealed that the Singers are secretly breeding a horde of captive skymouths rather than killing them in the course of protecting the city, as they claim.

    Live-Action TV 
  • Agents of S.H.I.E.L.D. reveals the Project T.A.H.I.T.I. that revived Agent Coulson revolves around draining the fluids from a Kree corpse. One of those was the regenerative serum that causes terrible psychological consequences unless the test subject's memories are changed. And this was apparently the least horrific serum.
  • Doctor Who:
    • In the story "Nightmare of Eden", part of the plot involves the spread of a new addictive drug, and another part of the plot involves a pack of alien monsters roaming around after escaping while being transported by a zoologist. It turns out that the zoologist is the kingpin of the drug operation, and the drug itself is derived from the alien monsters.
    • Much, much later in "The Beast Below", we get Spaceship UK built around the monster and using it as an engine. And it's a nice, helpful monster, turns out. It doesn't mind being used as an engine and will happily take the spaceship where it needs to go... but the operators of Spaceship UK didn't know this, and thought they had to torture the poor thing to get it to move. This ends once the Doctor shows up, and the creature begins moving much faster when the torture stops.
    • In "Thin Ice", the villain arranges for people to get pulled through the frozen Thames's ice to feed a giant sea monster that's chained to the riverbed. Then he has its poop dredged up as fuel for his steel mills.
  • On Forever Knight, a vampire doctor used injections of her own blood as a "miracle youth-restoring treatment" marketed to aging rich people.
  • Grimm: Inverted in an episode where Wesen are killing ordinary humans in order to dry and powder their organs, which are sold for medicinal purposes including "male enhancement".
  • Jekyll has a secret society that is trying to recreate the circumstances that caused Henry Jekyll to transform into Mr Hyde, in order to revolutionise medical science.
  • In Lexx, Kai was animated by "protoblood", a secretion from the last of the Insects. Re-animated assassins like him were part of how His Divine Shadow maintained his tyrannical grip on power.
  • Monsters: In one episode, barbers made a mutually beneficial pact with vampires. Vampires have apparently evolved into giant immobile leeches and need the barbers and their customers to offer them their blood. In return, the barbers and customers are given small amounts of the vampires' blood which greatly extends their lifespans. The red swirling barber poles are symbols of the "blood for blood" pact. The narrator and his friend who initially intended to expose the barbers' connection with vampires become customers after tasting the vampires' blood. It helps that nobody is really being hurt in this arrangement.
  • Moonlight (2007): One episode involves a new drug called Black Crystal, that makes a human feel the high of being a vampire for a few hours. Naturally, it's produced by "milking" vampires. Unfortunately, keeping vampires sedate involves poisoning them with high amounts of silver, which make its way into the drug, eventually resulting in silver poisoning in the humans who take it. The "drug farm" was maintained by a 700-year-old vampire named Lola (a former Pirate Girl), who has no compunctions about using fellow vampires for this purpose.
  • In Powers, a Playstation Network original series based on the comic book series of the same name, the ability-enhancing drug Sway is synthesized from Wolfe's blood. This normally wouldn't be a big issue, but Wolfe wants it all back, and then some.
  • In The Sarah Jane Adventures first episode, the Bane Mother's excretions are the main ingredient in Bubble Shock cola "It's organic!"
  • Stargate SG-1: In "Cure", a civilization keeps a Goa'uld queen (actually the dying Tok'ra queen) captive in a tank so they can harvest her symbiotes to make an elixir that can cure any illness.
  • Supernatural:
    • Sam does this a bunch of times with demon blood. He uses it during the season 4 arc to enhance his psychic capabilities to be able to remove a demon possessing a victim without harming the host. He then becomes somewhat addicted to the substance, even keeping a victim possessed so that he can "bulk up" for the final fight.
    • In Season 13, Asmodeus has for the last several years been stealing Gabriel's grace to shoot into his own veins.
  • The 10th Kingdom has rather literal fairy dust, as in the dead remnants of a fairy, which is recreationally snorted by trolls.
  • Torchwood:
    • Inverted in "Children of Earth", in which the 456 want our children so that they can get high off them.
    • In another episode, a small group of humans exploit a Space Whale with a Healing Factor stranded on Earth; they use it for a cheap source of meat to wholesale.

    Tabletop Games 
  • In Aberrant, there are several illegal drugs (most of which will temporarily give a baseline superpowers) made out of the organs of novas.
  • In Age of Aquarius, vampire saliva is used to make a Laser-Guided Amnesia inducing drug. No profit on it is made, though, since the Institute, who owns the technology, is a noncommercial organization and it needs the drug itself to enforce The Masquerade.
  • Dungeons & Dragons:
    • Up through 2nd Edition, the game had extensive rules for using monster body parts for creating various magic items. By 5th Edition, the only remaining remnant of this is Dragon Scale armor, which as its name implies is armor forged from the scales of actual dragons.
    • Salamanders naturally generate intense heat from their bodies, leading some to summon and bind them to forges and ovens to use as endless heat sources.
    • In Exandria, the town of Tomb of the Worm was founded by settlers who found part of an Eldritch Abomination's body poking through the ice of the tundra, and discovered that its meat could be harvested and eaten as it quickly grew back. The abomination, Quajath the Undermaw, tolerates being eaten in this manner since it makes the townsfolk susceptible to being mind controlled and becoming his cultists.
    • Forgotten Realms:
      • Dwarven settlements sometimes keep captive deepspawn as a food source, feeding them livestock so the aberrations will make numerous copies of meat animals. This can easily backfire on the deepspawn-keepers, if one of their captive monsters ever manages to sink its teeth into something more dangerous than cattle.
      • Elminster's Ecologies details a number of practical uses for hydra body parts — their teeth can be used to make plows and saws, their hide dried and used as a cover for cold-sensitive crops, their tongues hung like flags to tell the weather from how they change color, their ground bones used as a desiccant, their fat mixed with cornmeal to serve as rat bait and their heads used as scarecrows.
    • There was an article detailing how a variety of dragons could be eaten. Red Dragon in particular, took a great deal of care to eat, or else the consequences could be dire
    • It's not uncommon for some players to just decide their characters want to cook and eat various monsters. Dark Mantles are like magic squid and Chuul are crustaceous in appearance, why not try a bite?
    • In Ravenloft, vampires from the Kargat secret police dole out their blood to human minions, the Kargatane, as a means of increasing their strength and delaying their rate of aging.
  • Exalted: First Age bioengineers created a breed of dinosaurs that can consume plants containing useful substances, process them in their bodies and pee out the refined chemical, which they farmed as living chemical refineries. Many breeds were created, each meant to produce a different substance, but most went extinct after the fall of the First Age civilization. Some still exist, however, and are farmed in the same manner as they were bred for — the most common is one that eats poppies and pees out heroin.
  • Pathfinder has several examples:
    • Enterprising, foolhardy adventurers can extract daemonic spinal fluid and alchemically process it into a potent drug. If you don't mind drinking a fiendishly addictive concoction that's Made of Evil and the digested remnants of damned souls, it gives quite a boost.
    • Cacodaemons can create soul gems when they consume a living being. This ability is valued by fiends and evil spellcasters alike, who often keep cacodaemons as living soul gem manufacturers.
    • Wealthy, foolhardy clientele can snort Mummy paste if they don't mind the risk of spontaneously transforming into an undead monstrosity. This is a case of Aluminum Christmas Trees: mummy powders and extracts were used as drugs on and off for centuries and as late as the 1920s, albeit — so far as anyone knows — without that particular side effect.
    • Shulns, gigantic rodents native to the Darklands, naturally produce two very valuable resources — the adamantine deposited within their teeth and claws and their potent paralytic drool. They're consequently often hunted to harvest their claws and fangs by people wishing to extract the valuable metal within or to collect their venom, although this needs to first be treated alchemically to avoid its normally rapid decay.
    • The bodies of furcifers, immense chameleon-like beasts with flowers growing from their backs, are extremely rich in valuable materials — their pollen and nectar can be used to make psychoactive drugs, their bones can be used to magic items related to acid, and their skin fashioned into cloaks and robes with illusory properties.
    • Ultimate Wilderness devotes a section to describing potential uses for monster body parts, focusing on how they can be used to replace spell and crafting components — a devil's tongue, for instance, contains the essence of law and can be used to replace any lawful spells when creating magic items; matter harvested from elementals can used to craft items pertaining to elemental powers or energy damage; troll livers, still holding their owners' Healing Factor, can be used to craft healing items; the organs that produce a dragon's Breath Weapon can be used to infuse items with the breath weapon's energy type; a demon's heart can be used to create any explicitly evil item; and so on.
    • In the fifth part of the Agents of Edgewatch Adventure Path, Belly of the Black Whale, the main villain is revealed to have captured and enslaved his former kraken master, whom he has spitefully hooked up to a complex machine that constantly drains his ink to use to produce the tabloids that the villain is using to secretly control society.
  • Salt in Wounds is a third party Dungeons & Dragons setting based on the idea of the Tarrasque — an immense, effectively unkillable behemoth that serves as D&D's iconic "top monster" — being bound in a canyon with enchanted harpoons and then used as a source of eternally regenerating meat, horn, bone and magical reagents. An entire city grew around the trapped beast, with entire orders of butchers arising to carve away into its flesh to then sell off across the world.
  • Shadowrun: One supplement's shadowtalk includes posts by a sicko who'd kept an Awakened leopard with a Healing Factor captive for years, periodically skinning it alive and selling the pelts. The same poster speculated about the possibility of catching a giant regenerating species of shark and selling its meat over and over again.
  • Warhammer: While the Empire is normally intolerant of monsters, as they're seen as expressions of Chaos, they have discovered certain monstrous species like the griffin have stabilized into essentially natural animals and are fantastic for riding into battle. As such, the Empire either has them privately housed at a Lord's manor or keeps in the Imperial Zoo (which even includes a dragon for the really desperate battles).
  • Warhammer 40,000:
    • The Imperium hates aliens and usually deals with them by a lasgun shot to the head. However some aliens have proven themselves useful and so certain Imperial factions have corralled them for their own benefit. One example are the Jokaero, a barely sentient species of orangutan-like aliens who are somehow master engineers and technologists. The Jokaero can be used to upgrade existing equipment or produce unique pieces of technology, such as rings that pack as much firepower as their pistol equivalents.
    • The Imperium hates Chaos with a passion, and for good reason, but they won't admit that humanity needs Chaos to function. The Warp is a very effective Faster-Than-Light Travel option, and the Chaos-catalyzed mutations that led to Psykers is necessary to train Navigators and to keep the Astronomican running. And there's also the practice of creating Daemonhosts, a forced Demonic Possession that results in a Sealed in a Person-Shaped Can situation for the Demon, who can then be interrogated.
    • One main source of Imperium food is Grox meat. Grox are dangerous lizard cow dinosaurs who need to be lobotomized. Ambulls, who are strong enough to basically be a Bonus Boss in the Blackstone Fortress tabletop game, can also be quite tasty (as pointed out in a Ciaphas Cain book and The Regimental Standard publication), and some of them are raised to be used as biological components and materials for the mechanical Ambots as well.
  • World of Darkness:
    • Vampire blood works as a drug. Consuming a vampire's Vitae gives a mortal access to basic vampire Disciplines and stops the aging process. When the Vitae is expended, aging not only resumes, but catches up, meaning really old ghouls will spontaneously die and crumble to dust if they don't get their fix.
    • Hunter: The Vigil: Three groups actively use the monsters they hunt in one way or another:
      • Ashwood Abbey sees monsters as good fun. One of their common reactions to meeting some new supernatural creature is, "Is there any way I can get high off of the internal processes of this being?"
      • The Cheiron Group treats monsters as sources of medicinal products. Their agents have access to Endowments that consist of supernatural transplants or chemical augmentations, all harvested from captured creatures of the night. Some are even put on the market as pharmaceuticals for public consumption.
      • The founder of the Malleus Maleficarum, Padre Ambrogino Baudolino, is a ghoul. He has Hunters bring him vampires from which to feed.
    • Mummy: The Curse has Last Dynasty, Inc, which has found that Sekhem, the energy that reflects the strength of a mummy's connection to life and magic, can be used to create healthier steroids, life extension treatments, and vaccines. They have become a pharmaceutical firm dedicated to making the world a better place, even if it means they have to reap this energy from mummies and the sacred artifacts they protect.

    Video Games 
  • BioShock: The little sisters, creepy shells of the children they once were, are organic factories of ADAM, the substance that powers the gene-manipulating plasmids, drug of choice for the Splicers that inhabit Rapture. Even the player has a choice to harvest them for a bigger payday instead of rescuing them.
  • Borderlands: The Pre-Sequel! has The Eye of Helios, a Wave-Motion Gun powered by the remains of the final boss of the first game fueled by Eridium slag. It is destroyed by Moxxi, Roland and Lilith to keep Jack from abusing its power.
  • In Chrono Trigger, the Kingdom of Zeal used Lavos as a power source once they discovered it, instead of the sun energy they had been safely using for years.
  • City of Heroes has the island of Cap au Diable, named for an oddly-shaped mountain which resembles a pair of horns. Local legend claims that a holy man sealed a demon under the mountain centuries ago. When the resident Mad Scientist goes to sink a geothermal tap, he discovers that the legends are true... and runs the tap right into the bound demon, producing vast quantities of cheap electricity. What could possibly go wrong?
  • In Darkest Dungeon, the Ancestor had a Decadent Court of incredibly hedonistic and carefree nobles, known simply as the Court. For pure sport, the Ancestor attempted to kill a visiting noblewoman known as the Countess, who turned out to be a colossal and ancient insect-like vampire queen. After wounding her, he added her blood to the wine served at the Court, for pure hedonistic excitement. Those nobles who drank the wine turned into mosquito-like vampires, while the Ancestor took a single taste of it, revealing the eldritch horrors of the world to him and starting him down the path to unearthing the titular Darkest Dungeon.
  • Disc Creatures: One chapter focuses on a gang killing bubble-like creatures known as Babool to harvest their tears.
  • DmC: Devil May Cry has an example that is basically the same as the Futurama example below, where a popular energy drink is really just the spewings of a succubus.
  • In DOOM (2016), the Union Areospace Corporation solved a worldwide energy crisis through the discovery of "argent energy" on Mars, which happens to be harvested directly from Hell itself. On the side, the UAC also dabbles in various ways of militarizing Hell, such as weapons that utilize argent energy, captive demons augmented with cybernetics, and undead super-soldiers animated by argent radiation.
  • In Dragon Age: Inquisition, it's revealed that the Qunari have captured the Ataashi, a poisonous High Dragon, for this purpose. They're extracting the venom as an ingredient in gaatlok, a form of gunpowder. The Inquisitor can either kill the Ataashi themselves, or release it and let it have its revenge on its captors. Either way, the production of gaatlok is stopped.
  • Dwarf Fortress: With some careful effort and luck, it's possible to capture a giant cave spider. With even more, very careful effort involving a cage-deconstructing mechanism, a drawbridge, a penned animal, fortifications, and other things it's possible to set up a safe giant cave spider silk ranching operation. Giant cave spider silk is an enormously valuable cloth, but risky to gather in the wild (what with the giant cave spiders that produce it still about) and this method mitigates that danger.
  • Fallout: Ghouls, humans heavily scarred and deformed by radiation, are healed by further exposure to radioactive emissions. Consequently, in Fallout 3, the Chop Shop infirmary keeps a pair of caged glowing ones — ghouls so irradiated that they became mindless and feral and literally glow green — around as a source of radiation with which to heal ghoul patients.
  • Far Cry 5: In Lost on Mars, Hemoleum — a material you collect to turn into weapons and other equipment — is produced by the Arachnides in a way that's compared to honey as it's made by bees. ANNE has been harvesting Hemoleum from them for who knows how long, which might explain why the crabs are so pissed at her.
  • In Final Fantasy XIV, it is revealed that one of the many ways in which the magiteknology of Allag was advanced was in their ability to harness primals, semi-sentient masses of aether in the form of ancient gods, as power sources. The artificial moon of Dalamud was part of a project to harness the power of the imprisoned Bahamut to power the entire Allagan civilization through the Crystal Tower, but it only resulted in the sixth Umbral Calamity. The Ultima Weapon, similarly, can increase its power by absorbing primals, although this has the unfortunate side effect of priming the Weapon's Fantastic Nuke.
  • In Five Nights at Freddy's 3, the managers of Fazbear's Fright are former Freddy Fazbear fans who decided to create a nostalgic horror museum based upon the now-dead Freddy Fazbear's Pizza and the infamous stories surrounding it, up to and including digging up and reusing one of the killer animatronics from before the original game. Said animatronic is also the suit originally used by the child killer who gave the pizzeria its infamy, only now with his corpse trapped inside following a Karmic Death.
  • Lobotomy Corporation: The profit margin is entirely based on using horrific abnormalities to harvest Qliphoth energy from them.
  • Minecraft has pretty much every type of mob drop useful items. Experienced players will even build mob farms to automatically slaughter mobs and harvest their drops.
  • Monster Hunter: The games' monster are hunted because they provide nutritious meat, they have body parts with supernatural properties for crafting, there's useful research to made from their remains or else their populations need culling. There's always plenty of zenny to be had when you take down a monster.
  • Pokémon Sword and Shield: the source of power for the Galar region, in addition to the source of the Dynamax phenomenon, is Wishing Stars, mysterious stones that emit Galar particles. As it turns out, Wishing Stars are actually fragments of Eternatus, an ancient and powerful Pokémon that nearly destroyed Galar in ancient times before being laid low by Zacian and Zamazenta. Rose, the Chairman of Marcos Cosmos and the game's Big Bad, wants to harness Eternatus as a perpetual power source for Galar. It doesn't work.
  • Shin Megami Tensei: Strange Journey: Every single monster giblet you collect can be sold to the R&D lab to be turned into a component for new armor or weapons.
  • Ultima VII had Silver Serpent Venom as the local super-steroid of choice; The Avatar could discover and ransack the facility where the Silver Serpents were being milked.
  • Vampire: The Masquerade – Bloodlines: In the sidequest "Thinned Blood", Vandal Cleaver is revealed to have captured a fledgeling vampire and kept her restrained to leech off her blood.
  • World of Warcraft:
    • The Undercity has an engorged Blight Worm chained up that periodically vomits out some green goop, which is collected and used by the Apothacarium in developing Blight and maybe other useful concoctions.
    • A good example is anything related to demon blood. Powerful demons are able to corrupt mortals with their blood. Though once corrupted, they seldom come back for more, they DO often server as lackeys prior to their reward of blood and, once corrupted, typically serve their masters. There are a few instances (notably Grom Hellscream) of characters who do return for another dose.
    • Kael'Thas and his Blood Elves are fond of this. They are capable of draining mana from any creature (one of the racial abilities even reflected this). Of note is their imprisonment of a Naaru to drain its energy for their paladins and of Magtheridon to drain his blood for Kael'Thas's Felsword Blood Elves. Kael'thas's master, Illidan, also used Magtheridon's blood to transform orcs and other servants.

    Webcomics 
  • Kill Six Billion Demons: Black Glass is a unique narcotic that can give a high to any species, even angels and devils. It's refined from the corpses of gods.
  • The Order of the Stick: A head-regenerating hydra which was incapacitated by the Order has become the source of meat for an enterprising goblin's hydra-head sandwich franchise.
  • This Is the Worst Idea You've Ever Had! has Nai'ka blood, which gives the imbiber magic power, at the cost of "burnout". Nai'ka are a race of naive cat-folk who usually don't comprehend hurting people. The practice is illegal, but, since they're not considered people, it continues relatively unchecked.
  • Zombie Ranch: Zombie blood turns out to have a myriad medical and industrial uses, leading to the existence of extensive farming operations where herds of zombies are corralled, fed and harvested to ensure a steady stream of high-quality undead blood.

    Web Original 
  • Mystery Flesh Pit National Park: The titular Mystery Flesh Pit is an indescribably vast, sessile macro-organism inhabiting the Permian Basin in west Texas. Up until 2007, Anodyne were extracting fluid from the Pit's ballast bulbs, mining building materials from its skeleton and marketing the whole thing as a tourist attraction, including guided tours into the thing’s interior.

    Western Animation 
  • In Futurama the favorite soft drink is Slurm, which is secretly 100% slug juice. As in, it comes from a queen slug. She and her underlings have built a powerhouse corporation by marketing this highly-addictive beverage.

    Real Life 
  • The venom of snakes is often extracted, both because it's required to make the antidotes to the venom and because it may actually have other medicinal uses in very small quantities.
  • Spider and scorpion venom have potential medical uses, making "milking" them worth the trouble despite each individual arachnid's supply being minute.
  • Honeybees were domesticated because of this trope: if not for wax, honey and the pollination benefits to surrounding vegetation, no-one would want to go anywhere near a hive of venomous, swarming insects.
  • Humboldt Squid, also known as diablo rojo (red devil) is crazy aggressive during feeding, and has been known to attack humans. They're also extensively caught for calamari.

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