Endgame may refer to:
- The 2011 Canadian crime drama Endgame.
- The post-apocalyptic LARP Endgame.
- The one-act Samuel Beckett play Endgame.
- The PlayStation 2 Light Gun Game Endgame.
- The open-source Strategy Game Endgame: Singularity.
- The 2000 film Highlander: Endgame.
- The Nancy Garden young adult novel Endgame.
- The Star Trek: Voyager series finale, "Endgame".
- The ending scenario of a game, most commonly referring to Chess.
- The content restricted to the highest character level in MMORPGs, see Role-Playing Game Terms.
- The subtitle of Avengers: Endgame.
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