Call of Cthulhu can refer to:
- "The Call of Cthulhu": The short story by H. P. Lovecraft that inspired everything else on this list.
- The Call of Cthulhu: The 2005 film based on the story.
- Call of Cthulhu: A Super Mario World ROM hack by Yashum, where Mario ends up in R'lyeh and has to rescue a potential sacrificial victim from Cthulhu and his minions.
- Call of Cthulhu The tabletop game based on the Cthulhu Mythos published by Chaosium.
- Call of Cthulhu: Dark Corners of the Earth: Survival Horror First-Person Shooter videogame loosely inspired from The Shadow Over Innsmouth.
- Call of Cthulhu: The Wasted Land: Turn-Based Tactics videogame with some rules inspired by the tabletop game, set during World War I.
- Call of Cthulhu: The Official Video Game: A horror RPG developed by Cyanide Studio and published by Focus Home Interactive.
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