In the distant future (or at least 20 Minutes into the Future), humanity has declined, and animals (whether all of them, or a few certain kinds) become the new dominant species.
Here, the humans might be extinct and animals now roam the world freely; there might be scenes of them living on manmade living places if any of them existed at all. Alternatively, there might be only a few humans left, either scattered away or confined to a single location. They may have regressed (whether just culturally or outright becoming animals themselves) so that they can't form a modern-like society anymore; they're no longer the dominant species.
Sometimes, the animals might have become Funny Animals or Beast Men (which one it is depends on whether the work leans more to the comedic side and uses this trope to justify a World of Funny Animals setting or whether it leans more to the drama side and uses this trope to speculate a hypothetical future for social commentary). There may or may not be an in-universe "evolution" happening to them; here they have quite literally become the new "man". Furthering in this direction, the humanoid animals may even see the humans (if there are any) as "animals", either as a Human Pet, human cattle, etc.
Plots involving this setting might be about how animals live now that they're the dominant species, or they may focus on the few humans who tried to survive in the "new world" full of animals.
See also Uplifted Animal, which is how the animals become smarter.
- In Kamandi, the Last Boy on Earth, a great disaster killed off nearly all humans, with the few survivors lacking intelligence. In the meantime, races of humanoid animals rose up to take the humans' place on the food chain.
- Superman: An old Silver Age issue involves a species of super-intelligent giant ants from another planet, who were mutated by a nuclear war that wiped out the humans of their world. And yes, they're called humans, specifically, by the ants!
- Archie Comics' Sonic the Hedgehog says that the planet Mobius is actually Earth in the future. The alien Xordas dropped gene-bombs on it intending to devolve but uplifted the animals into Funny Animals as well.
- Don Lawrence's Storm is similar to Planet of the Apes except the time travelling astronaut returns to find Earth controlled by Fish People.
- In My Cage, humans are long extinct and the world is populated by civilized anthropomorphic animals of various species. Although the characters are aware humans once existed, the strip's focus on workplace humour means the reason for their extinction never comes up.
- Rock & Rule occurs on an Earth where humanity eradicated itself, leaving the dogs, cats and rats to ascend mastery of the world. It seems they can now interbreed, as none of the characters seem to fit neatly into canine, feline or murine physiology.
- Baaa, a picture book by David Macaulay, has sheep gain sentience and take over the world after mankind dies out. Their society quickly develops a lot of the same problems that drove human society extinct, with overpopulation, poverty, and a severe food shortage. Fortunately, the sheep leaders develop a new food product called "Baaa" that conveniently solves all three of those problems at once... Eventually, this drives the sheep extinct as well.
- City has two replacements for humanity, dogs and ants.
- "No Connection", by Isaac Asimov, takes place on an Earth where humanity went extinct. America is populated by a peaceful bear-descended race. The story ends with them expecting a conflict with ape-descended aggressors from Eurasia.
- "Null P", by William Tenn, sees dogs take over the Earth. Humans still exist, but they have given up civilization and it isn't even clear if they are sapient. They are adopted as pets by the dogs and later go effectively extinct.
- George Orwell's Animal Farm has a localized version of this, where the livestock overthrow the human owners of Manor Farm and establish a society where the animals are in charge. It becomes a Literal Metaphor by the end, where the pigs, the leaders of the revolution who by that point have sold out their ideals in favor of maintaining an iron grip on power, have become virtually indistinguishable from humans. Orwell intended it as a Roman à Clef satire of the trajectory of the Russian Revolution, with the pigs' leader Napoleon serving as a direct analogue to Josef Stalin.
- In Red Dwarf, while Lister was in stasis a radiation leak killed every other human on board the Red Dwarf and his cat's descendants evolved into a civilization of sapient humanoids in the cargo hold who worshiped him as a god. By the time Lister wakes up three million years later, the cats have fought a holy war over the color of his hat and left the ship, leaving behind a few infirm or idiotic who gradually died off until there was only one left on board.
- Saturday Night Live had a series of sketches called "Bear City" in which a meteor strikes an American city, driving the human population underground and allowing the bears to rise up and fill the roles formerly filled by humans. The sketches are notable in that the humor is driven entirely through action as the bears cannot talk.
- Mr. Meaty: In "Suburb of the Apes", Josh and Parker attempt to travel two months into the future to get a new game console. They accidentally end up in the 27th century, where a race of baboons have taken over the planet, the mall is an overgrown ruin and the only signs of humanity besides the duo are the skeletons littering the place.
- After The Bomb: A nuclear or biological war (depending on the edition) kills off most of the human race but mutates a wide range of other animals to human-level intelligence.
- Hc Svnt Dracones features the corporate colonies on Mars mass-producing human-animal hybrids called "Vectors" to repopulate the solar system after the Earth is destroyed by a nuclear war. In the successive centuries baseline humanity gradually goes extinct.
- Pugmire is set in a pseudo-medieval kingdom populated by uplifted dogs after humanity's mysterious disappearance.
- Inherit the Earth is a seemingly medieval world populated by sentient bipedal animals whose ancestors were uplifted by humanity before a plague wiped them out.
- Killer Instinct: In Riptor's ending in the original game, the genetic experiments Ultratech used to create Riptor end up dooming humanity and ushering in a second era of the dinosaurs.
- Paladog: After humanity is destroyed for its wickedness, animals take over to replace them.
- Splatoon takes place in a world where various sea creatures (primarily squids) have become the dominant species on Earth due to rising sea levels having led to the death of humanity thousands of years prior.
- Tokyo Jungle is set in a world in which there are no humans, the city of Tokyo is falling into disrepair without any maintenance, and a new ecosystem is forming in its ruins where multiple species of herbivores and carnivores compete for survival. The cause of this is eventually revealed to be humans from an apocalyptic future attempting to transplant themselves back to the 21st century with time travel, creating a Time Paradox which causes all present-day humans to vanish.
- In Jack, the world used to belong to humanity. That was until Jack killed them all, giving rise to the furry race.
- Unity takes place on a massive Generation Ship where the humans who originally crewed it seem to have gone extinct while the fauna evolved sapience in various ways. The main character is distantly descended from the platypus.
- Batman: The Brave and the Bold: In "The Last Bat On Earth", Batman gets trapped in the distant future where animals rule.
- Futurama: Earth undergoes such a change in dominant species in the future in "The Late Philip J. Fry". Several times over, as a matter of fact — after the apes take over, birds displace them, then cows displace the birds and then some sort of slug creatures displace the cows, as Fry realizes when seeing a series of ruined Statues of Liberty each modeled after a former dominant species.
- Peace on Earth takes place After the End, where animals have become intelligent and taken over the world after humans killed each other down to the last man in an apocalyptic global war. A 1955 remake (Good Will to Men) would change the exact cause to nuclear war.
- Rick and Morty: In "Lawnmower Dog", Rick creates a device that makes the family dog, Snuffles, intelligent. Unfortunately, Snuffles becomes too intelligent and ends up making every dog in the world smart and they take over the Earth. Good thing Rick and Morty saved the day... For now, at least.
- The Archie Comics' Sonic the Hedgehog mentioned above was written for the unmade third season of Sonic the Hedgehog SatAM. The main difference being that Robotnik and Snively were to be the only remaining humans due to being off-planet at the time.