Justice League Dark: Hecate is the goddess of magic. She is the first magical being in the universe, predating even predates other gods and is the one who taught humanity how to use magic. When some humans tried to steal her power, she split into five portions each hidden within a mystically empowered woman: Wonder Woman, Manitou Dawn, Witchfire, Black Orchid, and Circe.
Justice League of America: Wonder Woman is either a demigoddess or a magic statue brought to life by the gods, Zatanna is a trained sorceress and Vixen wears a magic amulet that grants her the power to copy the abilities of animals. These women are the most prominent female members of the Justice League (along with Black Canary who is a metahuman martial artist) and the most consistent mystic characters of the team. While Aquaman does wield a magic trident, he is normally the sole male mystic character of the League.
Gloss is a Chinese woman with long hair and a revealing leotard. She has the ability to manipulate Ley Lines.
Floronic Man is a Plant Person who possesses both male and female reproductive organs, something common in many plants. He draws his power from the Green, the mystical force which connects all plant life on Earth.
Betty Clawman is an Australian-Aboriginal girl whose powers revolve around the Dreamtime.
Shadowpact: The male members of the team are Blue Devil, a stuntman and martial artist who was turned into a demon, Ragman who wears a mystical suit composed of souls, Nightmaster who fights with a magic sword and Detective Chimp, a talking monkey. The female characters are the Enchantress, a powerful and clever sorceress, and Nightshade, a member of a Mage Species with shadow magic she inherited from her mother. The team is later joined by the angel Zauriel who is male and Warlock's Daughter, a young girl whom Enchantress takes in as her apprentice in the magical arts.
Suicide Squad: The Ostrander run featured four female mystic characters; in addition to the aforementioned Nightshade, Enchantress, and Vixen, there was Black Orchid, a Plant Person whose powers were tied to the Green, the mystical force connecting all plant life on Earth.
The first female Titan was Donna Troy, whose powers are often connected to Greek deities. Before the first DC reboot, Lilith Clay was a clairvoyant who was revealed to be the daughter of a Titan of myth.
Young Justice: The book's magic and mystic characters were all female; Cassie Sandsmark, a demigoddess; Anita Fite, a Voodoo priestess; and Secret, a ghost. All the other characters either had no powers or had abilities of a more scientific origin.
In one of Wanda's solo books, her first arc is about magic specifically practiced by women, witchcraft itself, being corrupted and her seeking a cause and solution.
Amora the Enchantress is renowned both for her skill in magic and her beauty, and when allied with Thor, she is easily the most feminine of his companions. She is notably contrasted with Lady Sif, Angela, Valkyrie, and Jane Foster, who more fit the female warrior archetype.
Angela's girlfriend Sera is a Transgender female sorceress. She was born as a male angel but always knew she was a woman. During her travels with Angela, Sera found a way to transform her body from male to female.
New X-Men: Academy X: Pixie learned a Teleportation spell from Illyana and wields a magic dagger that can harm astral beings. She is a teenage girl with pink hair and the only mystic character among the cast.
Runaways: In the team's first iteration, the only members with powers were Nico (who fought with her family's magical Staff of One), Karolina (who inherited light-based alien powers), and Molly (who had mutant Super-Strength). The other female character, Gert, had a psychic dinosaur, while the two male characters, Chase and Alex, were much more mundane.
The Ultraverse: In Mantra, Lukasz was one of eleven extremely experienced warrior whose served an extremely powerful sorcerer called the Archimage. Any time one of the warriors fell in battle, the Archimage would reincarnate them in a new body. This arrangement went on for centuries until one of the warriors betrayed the Archimage to his Arch-Enemy, the Evil Sorcerer Boneyard. The Archimage was captured and the other warriors were killed. As Lukasz fell, the Archimage used the last of his magical strength to reincarnate Lukasz into a new body: a woman named Eden Blake. The Archimage did this because he knew that without his brother warriors, Lukasz would need new skills to battle Boneyard. In Eden's body, Lukasz could use the latent magical potential of her bloodline, and the longer he was in her form, the more he could access this power, slowly becoming a vastly powerful sorceress.
Other Comic Books
Josie And The Pussy Cats: In the Archie Comics continuity, Alexandra Cabot is the only female roadie and the only one with magic powers. However, her magic rarely succeeds, either because her spells are fragile (one snap of Melody's fingers will negate them) or the effect goes wildly off target. At one point, she laments that "I seem to be some sort of inaccurate witch,".
The Coda are an all-female sect of Kherubim priestesses, fighters and assassins. They are also the only Kherubim faction with any knowledge of magic.
Voodoo's Daemonite powers are psychic in nature but she has also learned some voodoo magic such as necromancy.
Zealot's Arch-Enemy is Tapestry, a female sorceress and the only WildCATS villain with magical knowledge.
The Witch Boy: The main character Aster is part of a magical family in which boys are born to be shapeshifters and girls are born to become witches. Aster is a boy who wants to learn witchcraft but is forbidden by his family due to an incident in the past when his great-uncle learned witchcraft against tradition and caused chaos. It is ultimately revealed that Aster and his great-uncle are born with the ability to use witchcraft despite being male.
