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Mad Scientists in webcomics.


  • In the 70-Seas side story Mary Mendele, the title character is a Mad Scientist who is also a nun.
  • Abstruse Goose shows that being a mad scientist isn't that exciting in Real Life...
  • Celia of Addictive Science goes to a university for mad scientists, and is a bit trigger-happy with the transformation zappers she makes and keeps trying to take over the world (not too seriously though). And she's not the only one in the comic by a long shot.
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  • Annyseed has the crazy, charming, sometimes grumpy and a little suspicious, Yet lovable, Professor Tripadiculous. He likes doing tests on Monkeys. He has the documents required or that sort of thing too. So don't question him.
  • Arthur, King of Time and Space:
    • Morgan La Fey is an amoral sorceress in the baseline arc, but a Mad Scientist in the Western arc. And in the future arc, she's an amoral scientist and a Mad Sorceress.
    • The same webcomic also applies elements of the Mad Scientist trope to King Pelles and his daughter Elaine of Carbonek, and their quest to create the ultimate hero of Christianity (Galahad), by merging their line with Lancelot's. The newspost under the strip revealing this plan (and that Elaine is based on Helen Narbon) calls them "Mad Theologians".
  • In Bob and George, Megaman just loves working for one.
  • Books Don't Work Here has Sparky to fill this role, and while he only has a bachelor's degree he is far enough removed from lucidity to qualify.
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  • Al from The Brothers Quack, he got the inspiration for making Duck/Butterfly chimeras after he had a nightmare about turning into one himself.
  • Casey and Andy was created with the tagline, "Mad scientist roommates who periodically die." Both the eponymous mad scientists have, frequently, died, often at each other's hands, and often while indulging in mad science experiments. It doesn't help that one of them dates (a female) Satan, and their neighbour is an extreme Weirdness Magnet who is also an international jewel thief.
  • Commedia 2X00 features Professor Dottore, a cyberneticist whose experiments building Super Fighting Cyborgs got his funding cut off by the Institute Academy. Lives in an island fortress shaped like his head, occasionally yells things in Greek and Latin; labcoat, goggles, baldness.
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  • Cowbirds in Love observes that most mad 'scientists' are actually mad engineers.
  • Cyanide & Happiness has one too.
  • Jyrras Gianna in Dan and Mab's Furry Adventures. Dabbles in mixing science and sorcery (though he is not a wizard himself), invents a 'cosmetic patch' that alters one's appearance, builds hypertech weaponry out of boredom, and accidentally created new life forms twice (three times, if you count his part in the creation of the Mows). Unlike most mad scientists, he had enough on the ball to make a fortune from his inventions. His depiction in the Show Within a Show Spoof Spy Story depicts him as an actual one. He proceeds to subvert and lampshade various traditional tropes used by by Mad Scientist throughout the arc. (Such as while having a base in a volcano, it's dormant (The crater is in fact filled with orange pillows, not lava).)
  • Dr Nonami: Dr. Mechano is the classic variant of the mad scientist archetype, though the hero Nonami also has some minor aspects of this.
  • Eerie Cuties got professor Wilhelmina Twiggit. She's kind of fun. And always needs some guinea pigs. To the laboratory!
  • EVIL (the Elite Villain's Institute of learning) has an entire Mad Science department.
  • Dr. Tal A. Kinesis in Evil Plan The Webcomic, an almost textbook example. His pseudonym reflects the telekinesis he gave himself in an experiment. He has an underground lab filled with inventions, but he can't fix any of them himself. The reason? He's just the programmer, and after a fight the real inventor left to become his enemy.
  • Jordan Kennedy in Exploitation Now, an embittered and tragic Teen Genius who is the last survivor of a project to enhance human intelligence to super-human levels. Known for holding countries for ransom with stolen nuclear weapons and an orbital laser or two.
  • In Fans! there's a psychiatric wing for mad scientists. Professor Ignatius Fitz fits the trope to a T.
  • Far Out There has a supporting cast swarming with mad scientists. Hardly surprising when a major arc took place in a mad scientist convention.
  • Flintlocke's Guide to Azeroth:
    • The group of engineers who constructed the Ultimate Goblin Engineered Weapon.
    • Probably Flintlocke too, regarding weapon engineering.
  • In Frankie and Stein, the titular Stein is an adorkable Mad Scientist child, complete with Mad Scientist Laboratory.
  • Freefall:
    • Florence, a humanoid wolf and a main character, sometimes worries that her creator, Dr. Bowman, isn't entirely on the straight and narrow. Said wolf also thought breaking down stars for parts was a good idea...
    • Bowman has been confirmed as an example as well, but for unusual reasons. He's a genetically engineered chimp. While he's a bit eccentric, and openly obsessive about his work, he's also well aware of the self-control issues inherent to his status and has arranged for his entire lab to be padded to prevent him from damaging it.
    • Dvorak could be considered a robot Mad Scientist. His various experiments are done purely For Science!, and "Information wants to be free!" is practically a catchphrase for him. He's responsible for inventing robot poison, robot booze, at least one system for motorising a corpse, and the widely feared feral waffle irons.
      Dvorak: Also, I noticed your vacuum cleaner is underpowered. Would you like me to upgrade it to the megawatt range?
      Winston: Wouldn't that make the house implode?
      Dvorak: My owner asked the same question! The answer turned out to be 'Yes', but I know what I did wrong!
  • Game Destroyers had Dr. Fred Edison of Maniac Mansion as their army's mad scientist for a period of time. He was replaced by Dr. Benedict and Magnus von Tazar later on.
  • General Protection Fault has Nick Wellington and Dr. Wisebottom (his uncle), and Nick's evil Mirror Universe duplicate, Emperor Nick. There has been discussion of an "Inventor's Gene" running in the family.
  • Girl Genius:
    • The comic is set in an alternate timeline where "Mad Scientists rule the world. Badly." Here the trope is codified as 'the Spark' (implying a 'spark of genius'), and carries with it a strange charisma which binds minions to one's will - as well as an unfortunate tendency toward emotional outbursts of the "I'll show them all!" variety. Sane technicians and scientists are relatively uncommon, and often blend in with the crowd with Large Ham performances of their own. Centuries of Spark-to-Spark combat have left Europe a wasteland dotted with old wreckage, smoldering ruins, roaming monstrosities and the occasional heavily fortified town. Even the common people have adapted - those who have been under the protection of Spark dynasties for generations tend to fall readily under their spell as 'natural minions,' and are pleasantly surprised when they're not suddenly part of the latest experiment.
    • The protagonist is the latest in a long line of incredibly powerful Sparks, and has a habit of creating 'dingbots' (a Do-Anything Robot about the size of an alarm clock). She's such a powerful Spark that they show Sparky tendencies themselves, and build dingbots of their own (though each generation is increasingly defective). In other words, even her creations fit the Mad Scientist trope.
    • One of the prisoners in Castle Heterodyne (a dumping ground for mad scientists who are even more violently insane than the common-or-garden variety or have otherwise violated the Pax Transylvanica) is a mad social scientist, and none too pleased with how the hard mad sciences get all the funding.
      Doctor Mittlemind: I told the Baron, give me a thousand orphans, a hedge maze and enough cheese, and I could—
  • The eponymous characters of The Glass Scientists are all those - a kryptozoologist who turned himself into a werewolf, a man studying invisibility on his cat, Jekyll & Hyde... They're seen as public threat, but Henry Jekyll is attempting to rebrand them as beneficial for society.
  • Alexa from Gold Coin Comics is a top scientist for the empire's military. She has alluded to dangerous experiments conducted in the past.
  • El Goonish Shive:
  • Gunnerkrigg Court traditionally balances on the verge of this. Even not counting occasional pieces of Magitek. Starting from the creator of Court robots who did lose some important marbles from his head and his "children" are rather... fanciful — like non-flying Winged Humanoid "Seraph", or the cutest weather station you'll ever see. To trim the grass in park these guys happily use talking and learning robot cows with lasers in the eyes. And then there's Kat and her compact anti-gravity device highly customized crystallizer.
  • The Horrifying Experiments of Dr. Pleasant!: Dr. Pleasant has shark teeth and emotional problems and science, and he's not afraid to use any of them. He excels at revival from the dead via Monster Girl.
  • Molly the Peanut Butter Monster, Galatea the Other Peanut Butter Monster, and Dean Martin in The Inexplicable Adventures of Bob!. Poor Dr. Jean Poule would probably qualify as well, with her bizarre pet project which accidentally generated Molly – if not for the fact that Jean is, in many ways, the sanest person in the whole comic, a quality which in her universe is actually a bit of a handicap.
    • The Rogue Canadian Scientists and their buddy Slick are by far the straightest examples in the comic, though. The former are named "Dr. Madden McMadmad and Dr. Amad de Mademad," and Slick gets to shout, "Blind fools!!!! They called me mad! I'll show them! I'll show them all!"
  • Exoth from Irritability is a professional mad scientist who spends much of his time making things that are either random or actively harmful to those around him.
  • Jayden And Crusader: Smic, also known as Sir Reginald, is a British mad scientist of neo-Victorian style. His antics include, harnessing the power of sunspots to fill a house with pizza, defeating an acid monster with his bare hands and raising the recently deceased.
  • One of Jix's Multiple Personalities is Lamerix, formed from Remula's suppressed urge to build stuff. Stuff like death rays, interdimensional portals, gender- and species-swap beams...
  • Keychain of Creation has Elegant Nova of Progression. As mad scientists who may or may not be magitek robots themselves and occasionally get into fights with protagonists go, she's a pretty nice person; even her work to "upgrade" mortals seems to be reasonably consensual at least as far as the reader can tell, which isn't at all a given in the world of Exalted.
  • Last Res0rt: Dr. Daisy Archanis, although right now she's unable to be a proper mad scientist, since she lacks access to an appropriate lab. Didn't stop her from building her own robotic leg while incarcerated, though.
  • Eric, the nerd from Loserz, having a mad scientist moment.
  • Lovely Lovecraft: In backstory material and extras, Herbert West attempts to use science to resurrect the dead. This is consistent with his origin story in Herbert West–Reanimator.
  • Professor T.X. of M9 Girls! is more mild-mannered than your usual mad scientist. Still, his reasons for transforming his interns into the super-powered M9 Girls might not be just For Science!
  • Mad About U. is about a college for mad scientists.
  • Dr. Pilven from Maliki conducted experiments to attempt to recreate mnesic cristallisations, by giving cats to orphans that they'll become attached to, then killing the cat in the hope of triggering the cristallisation. His "scientific protocol" also involved drugging the orphans beforehand in order for them to be easier to control, and sending the cristallisations he created to fight against others in order to test their fighting abilities.
  • The Mansion of E: Sylvester's ancestor Ludwig, who left behind numerous dangerously useful magical-powered machines.
  • The hat of Baro from Marooned, except they're not evil. Suicidally reckless, on the other hand...
  • mezzacotta has Scott. The cast page claims he's not mad. Judge for yourself. Inevitable It's alive! It's alive! and, of course, For Science! Not that it was never called for. He doesn't always test things on humans right away. And sometimes he seems to be right. Others, such as Character #23 sometimes have recognizable fits of Mad Science as well.
  • Minions At Work: Offering An early retirement plan with a fresh, minty after-taste!
  • A Miracle of Science is set in a future where Mad Science is a memetically-transmitted mental disease.
  • In MK's The Strange Case of Dr. Jekyll & Mr. Hyde, Dr. Jekyll does qualify as one considering he tried to create a formula that would better people chemically though he did so with good intent only.
  • Lionel Flammel from Monsterful, though he's not really evil at all he seems to get really excited with his ideas, often making him commit terrible mistakes such as letting a huge Chimera free. His array of mad science includes making the perfect pet to making crime-fighting robot girls and who knows what else.
  • Narbonic has "going Mad" as an inheritable genetic disorder. The main characters are a mad scientist, her hapless lackey, her gun-toting assistant, and a superintelligent gerbil she created. Not only is mad scientist Helen B. Narbon a Card Carrying Mad Scientist but her mother (with whom she shares 100% of her genome) is also.
  • It appears that Franken from Noblesse has been one in his old days, which isn't surprising, considering his name. He even has an elaborate lab in his apartment and is very willing to use anyone for subjects, although it's mostly for harmless and frankly silly experiments, but it horrifies people anyway. It becomes especially evident if he unlocks his seal and unleashes his Superpowered Evil Side, which is the biggest source of horror in the series.
  • Nukees features Gaviscon van Darrin ("I'm not mad, just really disappointed"), Danny Hua (creator of the Giant Robot Ant), and His Royal Highness King Luca, Monarch of the Nuclear Engineering Department of U.C. Berkeley.
  • Most members of the Society of Inventors in Scary Go Round are in fact somewhat benevolent mad scientists. Other characters in the series (such as Archie Stanwyck and the monkey-obsessed Dr. Petrescu) are mad scientists pure and simple. Especially Petrescu, who's idea of a mobile phone is a normal landline strapped to a monkey's head.
  • Schlock Mercenary:
    • Several, most notably Kevyn Andreyasn. Also, his good friend "Gav" Bleuel (cryonically-preserved author of Nukees), who accidentally duplicated himself 950 million times, becoming one of the largest ethnic groups in the galaxy. But for Para Ventura, Kevin is not mad scientist enough. Until she discovers he's got anti-matter epaulets, which could be said to be madness, in a way
    • Para Ventura also fits the bill in her first mission, although LOTA is more adaptable than Dr. Frankenstein's monster.
  • Invoked by Skathi in The Senkari, when she creates a mortal in Frankensteinian style, complete with lightning.
    Skathi: It lives! ...I love doing that.
  • In one Sinfest strip, God uses a Mad Scientist puppet.
  • Skin Horse:
    • The series is a not-quite sequel to Narbonic, and is filled with the transgenetic products of said Mad Scientist types, including Sweetheart, an intelligent dog who's one of the heroes. Her creator Captain Bram is definitely a mad scientist. He plotted to take over the United States because the A.K.C. wouldn't recognize his genetically-engineered super battle dog as a registrable breed.
    • However, Dr Virginia Lee, the Black Ops scientist who created a nanotech zombie living weapon, transferred the brain of an antisocial gamer into a helicopter, and has a reputation as "a ruthless brain butcher" is not a Mad Scientist. At least, she doesn't suffer from Science-Related Memetic Disorder, however stable her sanity may or may not be otherwise.
      The Abbess: How is this not mad science, again?
      Dr Lee: Perspective!
    • Lee is one of the very few "sane" scientists capable of deciphering mad science and making it sane.
      Dr Lee: No! I´ll build my own, sensible brain vending machine!
      Sergio Mendoza: Step back from that sentence and reassess.
    • Tigerlilly Jones is a blaxploitation-themed mad scienist.
      Tigerlilly: You think I'm crazy because I don't know I'm not an Egyptian Princess reincarnated on Planet Lovetron. But I DO know. I'm crazy 'cause I don't CARE.
    • The guys at the Department of Irradiation also insist they're not Mad Scientists, it's a recognized DSM-IV disorder, they're just irresponsible.
  • Sluggy Freelance:
    • Dr. Schlock, time-traveling expert of Inflatable Technology, and Riff, a violently-minded tinkerer. And they're two of the good guys.
    • Dr. Crabtree, who created Y2k incompliant nanites that nearly killed off most of humanity, and turned herself into a nanite cyborg. And Dr. Steve Hereti, who claimed to have created Oasis and could control her via a wrist watch. And Dr. Scabmoreaureau, who created "Rock 'Em, Sock 'Em Gas", which forces two DNA strands to battle each other for supremacy to make genetic clean-up a fun game for the kiddies. Did I mention he's one of Santa's Elves? Yeah, Sluggy Freelance is lousy with Mad Scientists.
    • Sluggy also gives a pretty good explanation for why mad science is unrepeatable: Riff doesn't write down "no-brainers" in his notes, so when people try to replicate his inventions, they can't, since they're used to everything being exactly as written.
  • Mad Dr. Nesbit from Supermegatopia.
  • Tales Of Gnosis College is devoted to this trope. Examples include the relatively benign Professor Joseph Corwin and the not-so-benign Dr. Emil Strangeways.
  • Tales of the Questor:
    • The Artifactor's Guild, the Alchemist's guild and more tellingly, the entire student body of their University.... on a grimmer note, they have the historical figure of Rosad Athair Beither, a biomancer (essentially a biologist/genetic engineer) who was obsessed with the origin of monsters, and created monstrosities and conducted horrific experiments on helpless victims as part of his "research." More horribly, his discoveries had such shocking implications that the Racconan government put a stay on his execution till he finished compiling his notes.... and there is apparently a secret society of his followers still active in the Sanctuary City underground.
    • A later side-arc introduces a slightly more benevolent version, in the form of a biomancer attempting to gain sponsorship for his toxin-removing plants....
    • The protagonist and two of his friends (one an apprentice artifactor) managed to make an extremely powerful sword whose effects seem completely random, while drunk.
    • In this world magic lux can be scientifically analyzed, and makes up the bulk of Racconnan technology.
  • Frank from Two Guys and Guy. He's a sociopathic Serial Killer who probes aliens. He has also made several back-up clones for Wayne and plenty of unique devices.
  • Umlaut House and its successor involve several mad scientists, of both good and evil varieties, and had a Mad Science Convention.
  • May of Wapsi Square was most likely one of these back in the day. Her inventions and plans have resulted in a few end of the world scenarios.
  • Wayward Sons: Doctor Chu is a small being resembling a rat, who is a brilliant scientist. He also happens to get a lot of his results by performing torturous experiments on live subjects. And it's often not for science.
  • The Whiteboard has Doc and Roger, though Doc focuses on paintball and military hardware. If you pay attention to the forums, Doc is also a Mad Scientist in Real Life, being a machinist with a penchant for mayhem.


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