Ace Attorney Investigations: Miles Edgeworth has Bullmoth, a giant lizard-bull hybrid that stars in an in-universe movie. In true Kaiju form, it's facing off against another big monster from the franchise, Gourdy.
Aliens: Armageddon introduced kaiju-sized aliens to the franchise, as bosses which are practically immune to gunfire and can only be defeated by firing grenades at certain weak spots. The largest of them all, the Winged Alien Queen, is taller than the evacuation rocket housing thousands of refugees.
Age of Mythology's expansion brings Titans to the battlefield. They're huge, they can trash a city on their own, and it takes a ton of firepower to bring one down. Don't let your enemy summon one.
Billy vs. SNAKEMAN: Kaiju are a regular occurrence. Kaiju will regularly attack villages, their digital shadows haunt the Fields as Phases, and Players completing The Impossible Mission will become a kaiju. There's also the World Kaiju, which are embodiments of hastily renamed other popular MMOs.
Borderlands features Vaults, which were made to contain giant monsters that typically serve as final bosses.
The first game had the Vault of the Destroyer, which everyone at first believed to be a cache of alien treasure but instead had a massive tentacled creature that the players have to kill.
Borderlands 2 had the Vault of the Warrior, which housed a biological Eridian superweapon in the shape of a colossal four-legged dragon made of magma.
Tales from the Borderlands had the Vault of the Traveler, which contained a giant, teleporting, bipedal rock monster that couldn't be killed with conventional means.
Brawl Stars: In the Super City Rampage mode the goal is to defeat a kaiju, and it's only a matter of time before it destroys the entire map.
Bug Fables: The Dead Lander Omega is a horrific... thing encountered in Giant's Lair that towers over Team Snakemouth, who are all small enough to potentially fit into its hands. It's the size of the Lair itself, and could easily crush not only the heroes, but all of Bugaria unopposed if it wanted to. But for reasons unknown, it prefers to stay in the Lair and patrol the area immediately outside of it, and will merely drop Dead Lander Gammas on Team Snakemouth if it sees them.
Civilization: Beyond Earth gives us three Colossal alien creatures: Siege Worm (Vermis Obsidione Colossus), Makara (Astacopsis Choanae), and Kraken (Vivens Bestia Insulae). These are very tough beasts, who automatically pillage improvements by simply moving and are difficult to kill until the late-game stage. However, for some reason, they will never attack your cities directly. Your Explorers can only "collar" them after a certain late-game tech is researched. Additionally, Harmony players can eventually build the massive Xeno Titan that dwarfs highrises (while the in-game figure may appear to be a case of Units Not to Scale, a loading animation depicting one clearly shows how incredibly huge it is). It's a genetically-engineered alienesque monstrosity completely under your control. Unlike the Colossal aliens, the Xeno Titan does not mess up your improvements and can even take advantage of your roads and maglevs (try not to think too hard about one of those things taking the train or the highway). There's not much an enemy can send that will take out a Xeno Titan, although they're certainly not indestructible, and they're excellent for sieging cities.
The NSFW game Corruptions of Champions has Venus the Turtle Woman, who is so large her shell is large enough to be mistaken as a small island. She grew so large due to the local demon factory dumping toxic waste in to the lake where she lives. Despite her imposing size, she's quite the softie. And being that kind of game, you can have sex with her, well as close to sex as you can with someone her size.
Crush, Crumble, and Chomp! gave the player four cities to destroy (Tokyo, New York City, Washington DC and San Francisco) and six monsters to destroy with (along with the ability to make your own monster). Later came The Movie Monster Game which played like a streamlined take on the same idea, with Godzilla himself available as a player character.
Daikaiju Daikessen is deliberately designed to pay homage to the aforementioned King of the Monsters. It's also a 2D fighting game and beat'em up, but this one has a much bigger roster comprised of a few dozen monsters. While many of them are Notzilla, their designs and attacks have a wide variety. Some are Earth-based deities, while others are invading gods from other planets and dimensions. There's about half a dozen mechas as well. There's also a giant mutated hydra, bird, moth, tiger, gorilla, lemur, elephant, fish, triceratops, squirrel...
Dawn of the Monsters: Nephilim are colossal monsters that come in a wide array of shapes and sizes, ranging from the mostly-organic first-wave Nephilim like Megadon and Ganira to the purely inorganic third-wave Nephilim. They are not carbon-based lifeforms, they do not need to eat or sleep to function, and their bodies are supersaturated with Sheol energy — which is capable of mutating humans exposed to it. First-wave Nephilim are unique entities capable of independent action, while second-wave and third-wave Nephilim are spawned en-masse by Nests or summoned by Monarchs — which act as a Hive Mind. It's implied they are Gaia's Vengeance incarnate, and manifested as a warning for humanity to treat the Earth with more respect, but they are ultimately revealed to come from another dimension entirely.
Destroy All Humans! 2 has the "Kojira Kaiju Battle" mission, a Godzilla parody complete with someone screaming "Kojira! Aieeee!", atomic breath, and those weird anti-Kaiju tanks common in Godzilla films. Naturally, it takes place in Japan.
Disgaea: FLONNEZILLA! Flonne's final attack as a fallen angel. She dresses up in a patchy dinosaur costume and starts terrorizing the targets, with toy planes on wires flying around her. She finishes it up by breathing fire on the target.
The Elder Scrolls IV: Oblivion has at least two. First and foremost is Mehrunes Dagon, Daedric prince of destruction, and Jyggalag, Daedric prince of order. Although Jyggalag is the smallest of the two, he is taller than the city walls and is very powerful.
Extinction: Fighting Kaiju-sized orcs is the main draw of the game.
Recurring monster Adamantoises and their kin actually grow larger by each installment. By scaling, they reach truck size by Final Fantasy VIII to X, to being almost as tall as buildings circa XIII. The largest of them all appears in Final Fantasy XV as a Super Boss, and its "shell" is actually confused for a mountain.
Final Fantasy VII: The WEAPONs are quite distinctly Kaiju, right down to incoherent roars, being vaguely humanoid, coming from the depths of the ocean, attacking major population centres, and making craters on the main map screen when finally killed.
Final Fantasy X: Sin, the main threat, is a giant whale-like creature specifically meant to destroy cities that grow too large.
Final Fantasy XVI: Eikons, the game's take on summons, are this. They vary in size, with Ifrit and Phoenix being on the smaller side, while some like Titan are easily over ten times their size. Regardless, each Eikon is capable of collateral devastation similar to real-life weapons of mass destruction.
Guilty Gear: Megadeth-class Gears. Most Gears are vaguely human in size, and unless they're in A Form You Are Comfortable With, human looking too. This is not the case with Megadeth-class Gears, which are utterly titanic and wouldn't look out of place tussling with Godzilla. One Megadeth-class, Hydra, threatened to destroy London, but through the efforts of Kliff Undersn, the thing's advance was halted for a week so it could be targeted and destroyed with Last Resort, a magic Kill Sat with a several-kilometre blast radius. There was another example of a Gear the size of Mount Everest going up against the main character, Sol Badguy, and... being thoroughly obliterated down to ash and dust.
Hakaiou: King of Crusher have your salaryman protagonist getting infected by an alien virus that makes you highly susceptible to violence as you start developing monstrous forms, from a reptilian-werewolf man to a building-sized monster. And as the game progressed, you gradually lose control of yourself as you become a skyscraper-sized Not Zilla going on a rampage across New York.
Kaichu - The Kaiju Dating Sim is, as the subtitle states, a Dating Sim in which the player controls a Kaiju and courts others by taking them on dates to famous landmarks and completely destroying them.
Kaiju-A-GoGo involves players taking on the role of mad scientists who create giant monsters to dominate the planet.
Kaiju Wars is a Turn-Based Tactics game where you, the mayor of a megacity, must fend off attacks from several different kaiju. There's Alphazaurus Prime, a hirsute Notzilla; Megalodonkus, a King Kong Copy; Duggemundr, a giant armored worm/snake creature; and Pterus Ignis, a fiery Giant Flyer.
King of the Monsters, a Kaiju wrestling game. Its sequel is a sidescrolling beat-em-up.
Mass Effect 3: has Kalros, the legendary mother of the Thresher Maws. Regular Thresher Maws are already low-end Kaiju, being ~90 meters long (albeit only ~30 meters in height above ground, for 2/3 of their bodies will be underground at all times) and maneuverable, with acid spit that can dissolve tanks and a natural armored carapace that can resist shots from 155mm hypervelocity coilguns, and Kalros surpasses all her race in size. To put Kalros' size in perspective, the surfaced part of her body alone is already over twice the full length of a standard Thresher Maw, and even dwarfed the 160-meters long Destroyer-class Reaper she fight, and that was just the third part of her full length.
Mega: The only other character in the game besides James Ward is the giant monster that's ravaged the city, downed James' helicopter, and killed his crew. It also has keen enough eyesight to spot him, and will attack him at the first opportunity.
Metal Gear Solid 2: Sons of Liberty: The character designer Yoji Shinkawa was disappointed with the design of GodzillaIn Name Only in the notoriously half-assed Roland EmmerichGodzilla (1998), and so designed Metal Gear RAY's body, movements and Mighty Roar after how hewould have redesigned Godzilla to look. There's also allusions made both in-game and in Word of God comparing Solid Snake to Godzilla and Raiden to King Kong. Parodied in the non-canon Metal Gear Solid: VR Missions and Snake Tale E: External Gazer, where having giant Kaiju versions of the game's standard Mooks is kind of a recurring in-joke. Genola is just a giant Genome soldier in white Arctic camouflage, and Gurlugon is a Gurlukovich soldier with fins along its spine and the ability to shoot paralysing Eye Beams. The one narrative game mode featuring them never mentions their guard-like appearance at all and has Gurlugon simply regarded as a sea monster, possibly referencing Special Effect Failure (however, when battling Gurlugon he has similar weaknesses to the in-game guards, like a fondness for pornography, and he will carry Raiden off Fay Wray-style if you have him put on a Gurlukovich uniform).
Kraid is one of the largest bosses in the series, with his girth taking up two screens and his tail never fully rendered. His dinosaurian appearance and upright position even invokes the look of Godzilla. He seemed to grow several stories tall between Metroid and Super Metroid, but Metroid: Zero Mission retconned this out when it made him gigantic.
Metroid Prime: Federation Force: Rohkor Beetle is an absolutely gigantic beetle-like creature. Even compared to the Golem troopers, who are already much larger than usual due to their mech suits, this thing is huge.
Monster Hunter: World has Zorah Magdaros, the biggest Elder Dragon in the entire series: it's as big as a volcano and every bit as dangerous. So immense is its size that it qualifies as a Level in Boss Clothing, as the player needs to actually scale its shell to reach its magmacores.
Pokémon Ruby and Sapphire: Kyogre and Groudon. Sootopolis was the unlucky city that had front row seats to their coming. Heck, when the time came for Pokémon Adventures to adapt the Ruby/Sapphire games, the artist said that he wanted to recreate scenes from his favorite monster movies when he was drawing the volumes that involved those two's disaster-filled awakening and eventual battle.
Tyranitar, Hydreigon and Volcarona seemed to have been inspired by Godzilla, King Ghidorah, and Mothra respectively. Many more Pokemon are based on or at least can be compared to famous Kaiju (like Aerodactyl to Rodan, Clawitzer to Ebirah, Aggron to Bulgasari, and Blastoise to Gamera). In fact, there's an entire breeding group of Pokemon that all resemble Kaiju (known as the "Monster" egg group).
Pokémon Legends: Arceus gives us the Noble Pokémon Avalugg, Lord of the Tundra, the boss of the Alabaster Icelands whose Frenzy must be quelled. Noble Pokémon are already larger than their standard counterparts, but Noble Avalugg goes further than any of the others, dwarfing the player character with a size comparable to Sword/Shield's Dynamax Pokémon. He even uses a Breath Weapon not too dissimilar to Godzilla's atomic breath, firing off an Ice Beam during his battle. In the lore, at least according to one NPC, ancient Hisuian Avalugg were said to be truly gigantic.
Pokémon Scarlet and Violet gives us Iron Thorns, Tyranitar’s paradox counterpart who seems based on Mechagodzilla.
Psychonauts: Spoofed by the Lungfishopolis level: one mind is portrayed as a city of tiny lungfish-like creatures, meaning that Raz is gargantuan compared to them. Due to his distinctive headgear, the citizens immediately nickname him Goggalor. The Boss Battle of the level is the Villain with Good Publicity kaiju, who's hailed as a hero to protect them from "Goggalor" (and a Shout-Out to Ultraman).
Rampage: Choose your monster from King Kong, Godzilla and the Wolfman - sorry, George, Lizzie and Ralph - and go tear up Chicago.
Resistance 2 has the Leviathan, a giant monster that roams the flooded streets of Chicago.
In the Taiwanese video game franchise Richman, which is similar to Monopoly, there's a card called Monster, which summons one to wreck and destroy a house on a property.
Shadow of the Colossus: Every fight is against a titular colossus, the smallest being at least twice the size of the player character and the biggest being roughly the size of the Statue of Liberty. You have to kill them all with just some wooden arrows and your average-sized sword.
SimCity: One of the possible disasters is to have the city destroyed by a rampaging Bowser.
Spore gives us Epic Creatures which you can encounter early on in the creature stage. Later on in the Space Stage, you can make your own and send them to destroy cities for you!
Star Wars: The Force Unleashed II has the Gorog, a titanic gorilla-like creature which can hold a full sized rancor in its palm. Keep in mind that in Return of the Jedi, Luke came up to about a rancor's knee.
Stellaris usually spawns a handful of habitable worlds with the Titanic Life modifier, meaning the planet has an ecosystem where pretty much every native creature is kaiju-sized by our standards. The modifier's icon consists of a bipedal, vaguely humanoid creature at least twice the height of the mountain range next to it. A special event lets you try and make contact with them (or just hunt them to extinction if you're the xenocidal sort); succeeding results in some of these leviathans joining your armed ground forces, forming armies that can annihilate multiple regular armies with little difficulty. However, if the event backfires, the titans turn against your colony instead. It's generally advised not to draw their attention unless the planet is heavily fortified against ground invasions.
In the second Submerged game, the monstrous Big Man certainly qualifies. Images of the Mass rampaging in the City History collectibles suggest it can be even more deserving of the title when roused to rage, although it's immobile and passive toward the siblings during actual gameplay.
Some of the larger Leviathans of Subnautica fall into the size category of kaiju, particularly the extinct ones encountered only as fossils. The Sea Dragon Leviathan earns bonus points for its Godzilla-like ability to breathe fire, and for one of them having destroyed an Architect facility.
Sunless Skies: The Aeginae are said to be as big as mountain ranges. Going by some of the Spectacles, it's clear that some of the famed star beasts only mentioned before in Fallen London and Sunless Sea are clearly big enough to qualify and not exaggerated in the least. Case in point, the Grave of the Silent Saint looks like the results of a Mutual Kill between a Bazaar-like star messenger crab and a Storm-like star dragon, and they're bloody huge, like one could found two whole cities on their corpses.
Super Mario Bros.: Bowser, in many of the later games, has the ability to turn into Giant Bowser/Giga Bowser, becoming a full-stop kaiju. In this case, he resembles a more evil version of Gamera. One event battle has a giant Bowser facing off against a giant Donkey Kong in a cityscape — Godzilla and King Kong in New York, basically.
Ultra Series: Kaiju Buster Powered has plenty of Kaiju. However, as it's also heavily inspired by Monster Hunter, said Kaiju are more than capable of being taken down by humans with swords and energy weapons.
The Dragon Aspects are huge. Fore reference: The tallest playable race in the MMO, the Tauren, have males that are around 8'6. A Tauren player barely comes up to the top of Alexstrasza's claw. However, Deathwing, as shown in the trailer for Cataclysm, and the game proper takes the cake. He's described as "airliner big". Conservative estimates put him smaller than a Boeing 747 (specifically about 200ft long, 91ft tall, and a wingspan of of 400ft), maximum estimates put him on the scale of GODZILLA from the new movie.
At BlizzCon 2010, the cinematic artists said that they designed Deathwing with the idea that he had a 1,200 foot wingspan in mind. Going off of the Dungeons & Dragons system, where the wingspan of a Dragon is around twice the length of the Dragon's body, this means Deathwing is SIX HUNDRED FEET LONGnote That's bigger than Legendary's Godzilla, so the maximum estimates are more likely correct. Or his body-length:wingspan scale could be 1:1 and he's actually 1,200 feet long.
Galakrond, the "progenitor of dragonkind", takes this up to eleven. He's so massive that his full body isn't even seen in game, just parts of his skeleton. The artwork◊ of him from the novel Dawn of the Aspects shows that he utterly dwarfs the Proto-Dragon forms of the Aspects. For scale purposes, that's a small mountain below his right foot on the bottom left of the picture.
X-COM: Apocalypse has the Overspawn, giant aliens dropped by the Mothership for the sole purpose of rampaging all over the cityscape. They're actually pretty weak since they're usually up against the best of X-COM manufactured vehicles and weapons by the time they appear. Some players just leave them alone since they have a tendency of accidentally killing themselves when they get too close to a building they knock over.
◊ of him from the novel Dawn of the Aspects shows that he utterly dwarfs the Proto-Dragon forms of the Aspects. For scale purposes, that's a small mountain below his right foot on the bottom left of the picture.
