- Power Girl, her adult self from an Alternate Universe, saving her life and then bonding with her. Usually, when two superheroes meet, there's a slugfest, but Kara and Kara touch and are immediately assaulted with each others' memories. There's a bit of teasing ("You don't think that outfit is a little too revealing?"/"I got it out of your closet!"), but they end up liking and admiring each other so much. It's especially sweet because Power Girl was earlier shown going out of her way to avoid Supergirl, not wanting to cause some kind of paradoxical explosion.
- After the Downer Ending of issue 23, issue 24 ends on a happy note. Supergirl's body is restored, her kryptonite poisoning is removed, the entire collective of I'noxia is safe from Brainiac, and they escape Cyborg Superman's grasp. The collective thanks Supergirl for sharing her memories with them and remind her that her familiy's love is why she's alive. Before they part ways, they tell her to find happiness, because the search for it will truly lead her home.
- Issue 33 is a big one. After almost sacrificing herself to stop the World Killer (she's come a long way from the girl who thought Earth was just "a ball of sweat and mud") and finally getting off the Red Lantern ring, Kara's mind is finally clear of all the rage and angst that's plagued her since the New 52 started. She realizes that there may be a place for her on Earth after all, and she goes back to start over.
- After the end of the Red Daughter of Krypton's Kara phase, Kal and Kara have finally a decent, heart-to-heart talk in where Superman reveals that hes scared that Kara will sacrifice herself as Superboy did, and he is frightened of losing her last living relative.
Heartwarming / Supergirl (2011)