♫"Whoa, I feel like shit! This must be LOOOOOOVE!"♫
- For all their perverted tendencies, The Hormone Monsters genuinely care for the kids they are taking care of. Although misguided (as hormones often are), they did everything with the kids' best interests and nature in their minds.
- The fact that Nick's parents are very Happily Married and still in love after all these years, with a great sex life to boot. And they're also very much involved in their kids' lives and despite being somewhat inappropriate at times, they really do go out of their way to reassure Nick that they understand and empathize with the issues he's going through.
- Their warmth even extends to Nick's friends. They consider Andrew family and treat Jay infinitely better than his own family does, which Jay obviously appreciates more than anything.
- Coach Steve clearly cares about all the kids, although he shows it in some pretty bumbling ways.
- Jessi and Matthew's friendship. Matthew is normally mean and bitchy to just about everyone, EXCEPT Jessi, in fact she's the only one he's even remotely nice to and considers a friend, and he hasn't insulted her once, and he often takes the time to insult EVERYONE.
- Nick, Judd and Leah have a typical sibling rivalry, but they're always there for each other.
- Despite being a deadbeat stoner and constantly fighting with her mother, Jessi's father loves her and puts her happiness before anything else.
- Nick gives Andrew his pants after the latter jizzed himself and ruined his own pants (though it didn't help that Andrew tried to clean them in the toilet).
- Coach Steve accidentally buys marshmallows for Jessi instead of pads/tampons, but it's still nice that he tried to help her.
- Leah is very helpful and informative to Nick when he's writing his book report on a romance novel.
- Even though it's a joke, Jessi's conversation with her vagina is not only pleasant but informative. It ultimately teaches her that her body is not scary.
- After Barbara gets upset at Marty and accuses him of not loving her like he used to, he dresses up as Gustavo from the romance novel she's been reading. Sure, he messes it up a little, but it shows how much he cares about her.
- Nick declining a helicopter ride with a girl he likes because Andrew is afraid to fly.
- Missy closing her curtains around her face to Squee! when Andrew asks her to be his girlfriend.
- Coach Steve falls in love with the first woman to show him the slightest piece of attention, but she sees him as only a friend (due to her possibly correct assumption that he has some sort of intellectual disability). When she reveals this to him, he isn't upset or insulted but overjoyed to have a friend.
"You want to be friends? I can't believe you're putting me in the friend zone! That's like the number one zone!"
- Jessi and Matthew go along with Jay's magic act despite previously mocking him for trying it.
- Judd constantly insults Nick but is quick to say that he doesn't hate him and is happy to see him getting along with Tallulah.
- Maurice and Connie's meeting, in what's implied to be the first time they've seen each other in a while, during Andrew and Missy's kiss. They happily remember their first kiss back in Pangea, after the dinosaurs left in their rocket ships.
Maurice: It's good to see you Connie.
Connie: It's good to smell you.
- Nick happily helps Leah get revenge on Daniel after the latter assaults her at a party.
- It's a little weird, but Elliot comforting Jay after Nick reconciles with his mom is still sweet.
Jay: This is nice.
Elliot: You're wrong Jay. It's dyno-might.
- Andrew and Maurice crying in each other's arms after Missy breaks up with him.
- Jay and Jessi find comfort in each other to avoid their troubled families.
- Maurice's Heroic Sacrifice in "The Pornscape." Not only that, but when he pulls up his "sleeve" when preparing to fight, you can see Connie's name tattooed on his arm. Aww, he really does love her.
- In "Girls Are Angry Too" as the girls and boys are divided thanks to Lizer's sexist dress code, Nick at least attempts to try and see from both sides by not wanting to speak against the guys but also trying to speak up for the girls too despite getting heckled by both of them. Sure he fails, as he is only 13 years old and only knows so much, but his attempts are completely genuine in trying to diffuse the situation without taking sides and making sure his friends don't get into it with each other.
- Also, his and Jessi's hug definitely counts too when they reach an understanding and Nick listens to her rant and actually hears her out.
- Principal Baron can't even be bothered to remember the names of the students. But she knows that middle school is hard, so she says there will no longer be any uniforms or sexist dress codes.
- Jessi helps Matthew get together with Aiden.
- Jay's confusion about his own sexuality is resolved by a song from his new favorite character, as it teaches him that sexuality is a spectrum.
- Maury and Jessi are just as excited for Matthew's first date with Aiden as Matthew is, and help him out in anyway they can.
- Judd helps Nick get Cellsea back by breaking the lock of the box she's inside.
- Missy and Jay collaborating on Missy's erotic fanfiction in "Obsessed". It ends up leading to the two truly bonding. They openly share their opinions and suggestions and there's absolutely no judgment between the two of them (compared to the other interactions other characters have between each other).
- After Jay is left behind by his family when they leave for spring break and their house is fumigated, he goes to live with the Birches, who treat him as if he were a member of the family.
- Andrew's parents Barbara and Marty become known for their constant bickering and not exactly equal marriage no thanks to Marty's somewhat obnoxious and selfish attitude as they fought more than showed each other affection save for some moments. However, throughout season 3 their marriage almost seems stronger as Marty shows that he truly does love his wife and the two of them even spice up their sex-life as they make love rather passionately in both "Florida" and "Super Mouth".
- Similarly near the ending of Florida, Marty reassures Barbara when she's feeling insecure about her age and tells her that even after all the years, he still finds her as beautiful as the day they met. Likewise, he stands up to his even more obnoxious father in defense of his wife.
Lewis: Are you going to let your wife talk to me that way?
Marty: My wife can do whatever she wants.
Marty: Because she's one hot number six combo.
Lewis: What the hell is that?
Marty: General Tsao's chicken, with a spring roll, and your choice of soft drink.
Barbara: Oh Marty, that's your favorite.
Marty: No. You are.
- Even his niece Cherry is touched by his love for her as she can't help but go 'Aww!'
- In a really weird way Nick's interactions with Vicki have some heartwarming undertones given Nick's abysmal luck with girls (i.e Jessi, Tallulah, Gina...), and although Vicki is very eccentric and Nick can't tell if she's flirting with him or threatening to kill him, he still gets along with her and she has no problems hanging out with him as they sink a boat together and share a kiss. It's a bit nice to see Nick actually have a somewhat successful fling with a girl after his past failed relationships.
- Right after Featuring Ludacris stops Val and Kurt from attacking Nick, Nick returns the favor by pulling him away as Kurt tries to kick Featuring Ludacris.
- As Featuring Ludacris is bringing Nick home, he says: "My nightmare is over."
- Nick then lets him live in the attic of his house.
- After seeing a peek of what Jay lives through with his messed up brothers, Nick apologies to Jay and the two reconcile.
- In "Duke", it is revealed that Duke Ellington lost his virginity to the girl who dropped her handkerchief on the train, and that handkerchief is what he has been wearing as a memento. Then, as Nick lies back and listens to one of Duke's records, Duke and Maury have a heart-to-heart where Maury admits that Duke was his favorite child.
- For someone as desperate for affection as Lola, it's somewhat sweet for her that Ali says the former would be on the latter's list.
- We get a closer look at Matthew's friendship with Caleb and it is sweet. Caleb appears on the school news as a "statistician" reading lines that Matthew clearly wrote in an attempt to help him sound cool. Matthew also says that Caleb has a "beautiful mind" when he explains how the app calculates the rankings. As bitchy as Matthew can be, Caleb is clearly not one of his targets.
- Gina shares a rather sweet dance with classmate Charles Lu who as far as we know, has done nothing to objectify her or slut-shame her, and she seems genuinely happy as the two of them are even seen hugging while they dance, which is lovely to see especially considering all of the bullying and harassment she received in the previous season.
- Lars tells Missy that the reason he didn't make a list is because she'd be the only one on it.
- Ali sympathizes with Jay after he comes out as bisexual and gets a very lukewarm reception from his friends and classmates, who are either uncomfortable around him, or think he's just doing it for attention. Ali also confides in him the real reason she had to change schools, and then they dance together in a sweet moment of solidarity.
- When Jay tells Diane and Elliot that he's fine with the fact that he doesn't take the ASSes because no one cares, Diane tells him that they care.
- In "The ASSes" and "Super Mouth", Greg's taken more responsibility of himself, gaining a new job, a nicer apartment than in "Guy Town", and starting a new relationship. After his low in season 2, it's nice to see him starting to get his life back together.
- In "The ASSes", he talks Shannon down from putting so much pressure on Jessi after he notices how stressed it's making her.
- When Jessi decides to stay in bed due to the effects of Adderall and the Depression Kitty, her dad is the one who's able to get her to fight off the Depression Kitty's influence and go back to school.
- Connie gives Jessi the encouragement she needs to get over her anxiety and finish the test.
- She goes another route with Nick, and just tells him that he doesn't really care about the test and that it doesn't matter because he's charming, funny, and people want to be around him.
- Jay nominates Coach Steve to the Fab Five to help clean up his life and get his job back. Despite the odd nature of their friendship, Jay clearly takes it seriously and wants to do something nice for his friend.
- After Andrew tells Jessi that he saw Lola giving Mr. Lizer a foot rub, the two of them go talk to Lola and help her realize that Mr. Lizer has been taking advantage of her.
- Amidst the chaotic drama of the rest of the season finale, "Super Mouth", Jay performs another selfless act, this time for his highly dysfunctional family, by cleaning the entire house by himself. They're so moved by the gesture that his brothers start treating him nicer, playing with him in a more friendly way, and his parents are happily kissing.
- In "The New Me" Natalie returns comes to camp after coming out as trans and is getting treated badly from both the girls and the boys. Jessi comes to her defense and befriends her and they end up having a very strong friendship.
- Jay and Lola's relationship is equal parts heartwarming and hilarious. They are actually perfect for each other but that doesn't erase how their insanity fuels the other.
- After Nick bombs the talent show, Jessi tries to comfort him. He blows her off, but it's still sweet that she tried to look out for her friend, especially as everyone else seems to hate him.
- Seeing Andrew and Nick reconcile their friendship at the end of "Poop Madness" after all the shit they put each other through for the first three episodes is really sweet.
- Jay reassures Lola that she is beautiful after she becomes self-conscious about being 6 months older than him.
- At the end of "A Very Special 9/11 Episode", after feeling bad about taking advantage of Coach Steve's naivete for not knowing the significance of 9/11 other than it being his birthday, Matthew leads the bus in singing Happy Birthday to You! to him.
- Nick Starr contemplates bringing one of his parents with him to survive the end of the world. When he obliquely asks them via a hypothetical question, they both respond that they would rather die together, which is implied to be the only reason Nick Starr doesn't go through with inviting one of them to the ark.
- At the end of "The Funeral", Shannon ultimately lets Jessi live with Greg, seeing how unhappy living in the city has made her.
- Missy accepting "Mosaic Missy" as all parts of herself in her identity crisis in "Horrority House". Also a meta one since these are the last words said by Missy's old voice actress Jenny Slate before Ayo Edebiri takes over.
- The Gratitoad is the first supernatural being that isn't a Hormone Monster who doesn't torment everyone he talks to. He helps Jessi get over her anxiety and depression.
- "What Are You Gonna Do?"
- Duke helping out Nick when he's stuck as a lost soul and telling off Rick when the latter (seemingly) nonchalantly agrees with Nick giving up on himself.
- Even though she couldn't hear him, Maury tearing into Matthew's mom for being judgmental is still a really sweet gesture.
Maury: Matthew, step out of the room. I'd have a word alone with your mother...
[Matthew stands in the hallway, as glass-breaking sounds come from the kitchen and loud stomps shake the pictures on the wall]
Maury: ARE YOU FUCKING KIDDING ME, KIM?! YOU'VE GOT THE BEST GOD DAMN KID IN THE GAME, SO GET THE FUCK ON BOARD BEFORE YOU LOSE HIM!
- Marty tells Andrew he's proud of his son after Andrew slaps him in the face.
- After Matthew comes out to his father, his dad reveals that he knew all along. And he accepts his son the way he is, which is a huge contrast to how his mother reacted.
- The ending of "What Are You Gonna Do?" is a CMOH for Nick, when he takes the advice of his friends by breathing for four seconds (Andrew), accepting every facet of yourself (Missy) and being grateful for what you have (Jessi). He also reconciles with Connie.
- "My Furry Valentine":
- The interactions the Hormone Monsters have with their kids are downright adorable. The winner would have to be when Nick finds Connie at Lola's party and tells her that he's glad he has her in his life. Out of context it looks just like a love confession.
- Matthew and Jessi spend the day being single together. Matthew's attempts at being nicer are a lot less labored than they were in previous episodes, hinting that this might signal a real change for him.
- Jessi accepting her mother's relationship with Dina and telling her that she deserves happiness (after some encouragement from Matthew).
- Matthew finally meets another openly gay boy who swaps phone numbers with him.
- Judd inviting a girl up to his room for a candlelit dinner, coupled with his trained raccoons developing feelings for each other.
- Diane and Elliot don't get mad at Nick for blowing up at them because they understand that this is just part of him growing up.
- After dealing with the awkward tension between him and Gina from last season, Nick casually bumps into her at Lola's party and, after some awkwardness, sincerely wishes her a happy Valentine's Day with no ulterior motives whatsoever. Gina, for her part, returns the gesture resulting in no hard feelings between them.