- In the first episode Peepoodo suspects that Evelyn stole Mr. Rabbot's vegetables after seeing white fur at the scene. Evelyn responds with saying "I'm not a freaking vegan asshole."
- In "Papidoo and Mamidoo" the titular characters tramuatize Peepoodo after he walks in with them having sex. Papidoo then shows Peepoodo rather explicit photos of them when they were younger, including Mamidoo getting in an orgy, and he notes that's when Peepoodo's mother was concieved
- In episode 6, Peepoodo gets addicted to a Japanese Dating Sim, which makes Tuffalo freak out over him becoming an Otaku, with parodies of Goku, Pikachu, Misty, and a giant robot in the background.Tuffalo: Don't tell me you've become a fucking otaku no-life
Tuffalo: This fucking otaku Jap fanboy shit is great!
- However at the end of the episode Tuffalo has become addicted to the same game.
- Peepoodo promises to not jerk off more than 2 hours a day. Dr. Pussycat can only admit that it's a start.
- In "Body Swap" the first thing Tuffalo does in Dr. Pussycat's body is motorboat himself.