George H. W. Bush was a CIA director in the 1970s. "John Case" who was his VP's Agent X in the 1990s, said he was pulled off the Husk case by his then Vice-President (who would have been Dan Quayle, serving under Bush). Since the previous "Case" recognized the signs of a CIA-style cover-up, it stands to reason that Bush Sr had Quayle pull back his agent to keep from crossing swords with the CIA.
What did Richard Nixon do with his power under S5 as Vice-President, and what did he put Spiro T. Agnew up to in his tenure as Vice-President?
In fact, whatever did S5 do to make Washington bad in domestic/international politics? You have the US supporting various dictators in the Cold War, law enforcement going after local/foreign political activists, surveillance on minority communities after 9/11. The possibilities are endless.