The set of Troma's latest B-grade masterpiece is being terrorized by a sick serial killer. Who is this mysterious woman who's knocking off crew-members left and right? The answer will shock you! Or at least sicken you.
- Family Values Villain: Casey is killing out of a warped desire to promote 1950's-style family values.
- Fan Disservice: The fat naked guy running through New York.
- Fanservice: The constant female nudity. Also the young gay couple making out.
- Funny Afro: "Oh my god! He's got an afro!"
- Gainax Ending: The Movie Within A Movie's ending is just...hwa?
- Gorn: It's Troma. Of course there is.
- Groin Attack: Casey is finally done in by a boom mike through his vagina.
- Hermaphrodite: Casey, the reason he can disguise himself as a woman when killing.
- Real Life Writes the Plot: The story of how Larry's wife died is based on Lloyd Kaufman's appearance on the Morton Downey Jr show, where Morton worked the crowd into a frenzy, then assaulted Lloyd.
- Show Within a Show: The movie they're filming is another The Toxic Avenger sequel.
- Take That!: Pretty much a big middle finger to all the Moral Guardians out there.
- What Does She See in Him?: At the beginning, Jennifer has a crush on Casey, who's a total jerkass, even before you find out he's the killer.