The film takes place during the German occupation of Rome, specifically January-May 1944, judging by the reference to the battle of Monte Cassino. Giorgio Manfredi, an engineer in civilian life, is now part of an Italian resistance group. The Nazis know about him and are hunting Rome for him, so he escapes to the apartment of his friend Francesco, who is also part of the resistance. Francesco is about to marry Pina, who is carrying his child.
Giorgio was supposed to smuggle some money out to resistance fighters in the hills, but can't leave the city now that the Germans are looking for him. He approaches Don Pietro, a sympathetic priest, and asks him to do it. Don Pietro agrees...but the Germans are closing in Giorgio's little ring.
- As the Good Book Says...: Don Pietro says "It is finished." when Giorgio has been tortured to death by the Germans.
- Book Safe: A variation on this trope. Don Pietro is asked to carry some money to Resistance fighters. He's confused when the man he contacts hands him some books instead. As the man demonstrates, the books aren't real books, but Italian banknotes bound together between covers.
- Cold-Blooded Torture: The cells of the SS prison ring with the screams of torture victims. Near the end Giorgio is tortured with a blowtorch.
- Comforting Comforter: Francesco is looking after Marcello after Pina is murdered. He tucks Marcello in.
- Crapsack World: Wartime Italy.
- The Good Shepherd: Don Pietro, who is working with the resistance.
- Hand Gagging: Don Pietro has to Hand Gag an old man to get him to shut up as the Germans ransack the building.
- La Résistance: Giorgio is enmeshed with the Italian resistance—the "National Liberation Committee"—struggling to liberate their country after the Nazis occupied it in August 1943. All of his friends are working with the resistance as well. Even little Marcello, who is about ten, is leading his buddies in anti-German activities. They plant a bomb which blows up a fuel tank.
- My God, What Have I Done?: Marina starts saying "what have I done?" pretty soon after the Germans arrest Giorgio on her tip.
- Off-into-the-Distance Ending: After Don Pietro is executed on the outskirts of Rome, Marcello and his buddies turn away and walk back towards the city, St. Peter's clearly visible in the distance.
- Pietà Plagiarism: Don Pietro cradles Pina after she is shot In the Back by the Germans.
- Reveal Shot: Don Pietro and Pina are walking away from the church altar. They look startled but keep walking. The camera pulls back as they walk, eventually revealing that a Nazi officer is waiting for them. (It turns out he's a deserter from Monte Cassino.)
- Roof Hopping: Opens with Giorgio hurriedly ascending a flight of stairs to the roof of his apartment building, then clambering over a narrow gap to the next building. The Gestapo has come looking for him.
- Trust Password: Giorgio tells Don Pietro that when he takes the money to the men in the mountains, the man he's to give it to will be whistling popular tune "Morning in Florence".