Mousy, neurotic Myron Breckinridge (Reed) secretly receives gender-reassignment surgery in Copenhagen and returns to Hollywood as the glamorous, charismatic Myra (Welch). Posing as her own widow, Myra Breckinridge goes to her Uncle Buck's acting school, claiming that Myron is dead and that she is owed half the school and a huge inheritance. To pacify her while he verifies her claims, Buck gives Myra a teaching position. But Myra has much, much bigger plans.
Myra's ultimate goal is to save humanity from itself by destroying the entire concept of traditional masculinity, thus bringing about gender equality. She plans to do this by sleeping with a lot of people. Myra's unlikely partner-in-crime is...Myron, a mental manifestation of her former self. The two of them have already lined up Myra's first test subjects: Rusty, a young, hunky, clueless would-be actor, and his sweet, submissive girlfriend Mary Ann, who together represent the very binary Myra believes is the root of all human misery.
This synopsis makes the plot sound much, much more coherent than it actually is.
In reality, it's a psychedelic rollercoaster full of random public-domain movie clips, musical numbers, costume changes, over-the-top stereotypes, and a questionable grasp of how gender and sexuality (not to mention human beings) actually work. A legendary box-office flop, creator Gore Vidal later disowned it, the cast won't talk about it, and lead actress Raquel Welch once commented, "The only good thing about it was the clothes."
Myra Breckinbridge contains examples of:
- All Just a Dream: It's strongly suggested through the scenes at the start and at the end with Myron in the hospital that Myra's lifecomplete with Myron's own sporadic pop-ups as her alter ego, the last of which was him running her over only for her to die as himselfwas all a dream of Myron's prior to a sex change surgery that presumably didn't take. This is honestly the least unfortunate and terrifying interpretation of the story, and Rex Reed wouldn't play the part otherwise.
- Ambiguously Bi: Part of Myra's plan for world domination involves seducing people of all genders in order to break down walls between the sexes.
- And You Were There: Part of the All Just A Dream ending above. Myron awakes after his accident to find that his alter-ego Myra was inspired by a magazine cover of the real Raquel Welch and that Mary Ann is his nurse.
- Black Comedy Rape: In arguably the film's most (in)famous scene, Myra rapes Rusty with a strap-on, set to a psychedelic montage of old movie clips and one-liners.
- Blackmail: Myra blackmails Rusty into letting her "examine" him. She also blackmails Uncle Buck into giving her the job in the first place by pretending Myron is her late husband.
- Camp Gay: Irving, who wears makeup and jewelry.
- Casting Couch: Inverted by Leticia Van Allen, who does this with hot male actors rather than would-be starlets. (Her office has an enormous satin-draped four-poster bed hidden behind a wall.)
- Coming-Out Story: The film is basically a gay man's fantasy about his struggle with coming out of the closet.
- Corrupt Hick: Uncle Buck, though he isn't quite corrupt as he is just plain sleazy.
- Depraved Bisexual: Myra, who seems to be bisexual only to further her obscure, insane goals at the cost of other people.
- Dirty Old Woman: Leticia Van Allen (It's Mae West, what the hell do you expect?)
- The Ditz: Mary Ann.
- Dumb Muscle: Rusty.
- Double Entendre: Most of what Leticia Van Allen says.Leticia Van Allen: Hi cowboy, how tall are you without your horse?
Stud: Well ma'am, I'm 6 feet 7 inches.
Leticia Van Allen: Well, never mind about the 6 feet, let's talk about the 7 inches.
- Easy Sex Change / Magic Plastic Surgery: From Rex Reed into Raquel Welch.
- False Widow: Myra claims to be Myron's widow in order to get her own inheritance.
- Incompatible Orientation: Myra attempts to seduce Mary Ann as part of her plan to Take Over the World, only to be thwarted in the simplest possible way: Mary Ann is straight. Ironically, Mary Ann tries to let her down sweetly by saying that Myra is exactly the sort of person she'd fall for if only Myra was a man.
- Lovable Sex Maniac: Subverted and arguably deconstructed with Myra.
- Mind Screw: The entire movie is very bizarre and doesn't have much of a coherent plot.
- Protagonist-Centered Morality / Villain Protagonist: Myra is a seductive, manipulative, blackmailing, sex-maniacal sadist. It's unclear which of the two tropes she is, but she's gotta be one of them.
- Soundtrack Dissonance: Goofy music plays during a rape scene.
- Stock Footage: Old movie clips appear often, many times for comedy's sake. Many of the depicted people complained and sued about this, and the White House downright asked for the removal of a Shirley Temple clip given she was now an U.S. embassador.
- Take Over the World: Part of the motive for Myra's reassignment surgery is that she plans to singlehandedly destroy the very concept of gender by sleeping with everyone, thus bringing equality to the sexes. Or something.
- That Man Is Dead: Myra about Myron. He's a very lively ghost, though.
- Transgender: Myra.
- Unsettling Gender Reveal: Myra, when she lifts up her skirt and drops her panties in front of Uncle Buck and his lawyers, declaring "Gentlemen I am Myron Breckinridge!"
- Visual Pun: While Myra rapes Rusty, the stock footage shows a clip of dockworkers literally laying plank. This is probably the funniest of many, many such jokes used in the film.
- Wearing a Flag on Your Head: Myra's iconic star-spangled swimsuit.