- Take a shot when someone says "crap"
- Take another if it isn't Strong Bad.
- Take a drink if Strong Bad edits an email.
- Take a drink if Strong Bad, after reading an email, does something completely unrelated to the email.
- Take a drink when Homestar says "Seriously"
- Take a shot when Strong Sad says something depressing.
- Take a drink when Coach Z does or says something creepy.
- Take a shot when the King of Town eats something that isn't food.
- Take a drink when a character's lack of body parts is addressed.
- In a Halloween toon, take a shot when a character wonders what another character is supposed to be.
- Take a drink when the Cheat Commandos urge you to buy all their playsets and toys.
- Take a sip whenever someone dies in a Teen Girl Squad episode.
- Take a drink when a character impersonates another character.
- Take a drink if a female character who isn't Marzipan or one of the Teen Girl Squad appears or is mentioned.
- Take two drinks if the Poopsmith speaks or if it's implied he spoke.
Drinking Game / Homestar Runner