Take a shot every time Bulma abuses Jaco. You might need a new liver.
Down the whole bottle if Jaco gets back at her. Actually, you probably don't have to worry about that one.
Take a drink whenever Goku's tractor appears.
When he's flying away with it after Satan punches him, chug as long as he's in the air. On second thought, maybe save this one for if you're using a non-alcoholic drink.
Manga
Take a shot every time Toyotaro traces something from past material.
Meta example, if you're reading a chapter on a website, take a shot every time you read a comment that says the manga is better than the anime.
Alternatively, take a shot everytime someone says Super's manga is shit.
Anime
Take a shot everytime Beerus or Champa throws a tantrum.
Take a shot everytime Champa gets snarked at.
Two if it's by somebody other than Vados or Beerus.
If it's one of Goku's previous rivals or call-outs who didn't get the chance to really interact with him then chase your drink with a slice of white bread to kill your buzz even more.
Take a shot every time Marcarita's Verbal Tic kicks in.
Take a shot for every time Zen-o says something completely vapid and pointless during the Tournament of Power, and then Future Zen-o repeats the exact same pointless thing that Zen-o just said.