This gag-a-day comic strip focused on Priscilla Nutchell, her family, and her friends. Priscilla is a schoolgirl who begs to have her own horse and likes to spend excess money. Her father, Waldo (the "Pop" in the title), saves money by eating mashed potato sandwiches. Also in the family, Hazel is the mother and Carlyle is the son and elder child. Priscilla's friends are Hollyhock, who enjoys reading books; Stuart, who is bitter at Hollyhock, and Jenny Lu.
The comic strip also had a couple of color comic books in The '50s.
Priscilla's Pop contains examples of:
- Bookworm: Hollyhock. She likes to visit the library every day, twice on Saturdays.
- Ms. Red Ink: As mentioned, Priscilla is careless with money.
- Nice Hat: Hollyhock's and Stuart's hats. Hollyhock at least doesn't wear her hat in some of the final strips, but wears it again in the finale.
- Trademark Favorite Food: Waldo's mashed potato sandwiches.