The principal of Sheffield Institute.
- British Stuffiness: The cartoon gives her a British accent.
- Butt-Monkey: She sometimes becomes this due to the actions of the girls.
- I Was Quite a Looker: She doesn't say it, but in the comic she's shown to be a former beauty queen.
- Large and in Charge: A heavy set woman and is in charge of running Sheffield.
- Reasonable Authority Figure: Ms. Knickerbocker may seem strict, but that's only because she has to be when there are those who need it.
- Spinster: She hasn't been married and appears to be in her early 50s or 60s.
Taranee's main love interest throughout the series, a former bad boy trying to change his ways.
- Adaptational Nice Guy: He is introduced in the show as a former bad boy who becomes Taranee's love interest. In the comics, he starts off as a member of Uriah's gang and partakes in bullying up until his HeelFace Turn.
- The Atoner: He's desperately trying to shed his former bad boy image to prove to Taranee's mother that he has a genuine interest in his daughter.
- Catchphrase: In the show: "Sweet!"
- Crazy Jealous Guy: Once Taranee spends significantly less time with him after getting caught up in her extracurricular activities.
- Deadpan Snarker: Surfaces occasionally throughout both the cartoon series and comics, particularly when dealing with Uriah and his followers.
- Fiery Redhead: Shows more of this in the cartoon.
- Former Teen Rebel: He was previously a member of Uriah's gang, before reforming himself after meeting Taranee.
- HeelFace Turn: See Former Teen Rebel.
- Hidden Heart of Gold: He's a genuinely Nice Guy at heart, but isn't too keen on making this fact known.
- Love Redeems: Nigel's feelings for Taranee and hers to him, is what finally pushed Nigel to cease hanging out with Uriah's gang.
- Odd Friendship: He's revealed to be good friends with Martin.
- Put on a Bus: In the comics, after he and Taranee officially break up, Nigel isn't heard from or mentioned again. He's still Taranee's boyfriend in the cartoon.
- The Quiet One: Nigel is often described as being the "silent, reflective" type.
- Remember the New Guy?: When he's introduced in the show, it's mentioned he used to hang out with Uriah's gang, but this was never seen, unlike the comics where he was part of the gang from the start.
- Sensitive Guy and Manly Man: The Manly Man to Martin's Sensitive Guy.
- Troubled, but Cute
Hay-Lin's crush and eventual boyfriend throughout the series, who surprisingly moves away in the 5th saga.
- Chick Magnet: "L is for Loser" shows two cheerleaders practically fighting over him.
- Cloudcuckoolander: To lesser extent than Hay-Lin.
- Curtains Match the Windows: In the cartoon Eric has blue eyes and blue hair.
- Hand Behind Head: A frequent gesture.
- Headbutt of Love: Hay Lin and Eric first met when she was roller-blading and ran into his motor scooter.
- Mr. Imagination: His brain is described as being "bursting with imagination".
- Put on a Bus: He moves away when his parents return from their work trip in the 5th saga, and eventually disappears from the series.
- You Gotta Have Blue Hair: In the cartoon, his hair is colored blue.
A nerdy boy whose feelings for Irma seem to be unrequited.
- Abhorrent Admirer: To Irma.
- Adorkable: A genuine Nice Guy who is also a big dork.
- Extraverted Nerd
- Geek Physiques: He's scrawny and ungainly in appearance compared with the other boys in the series.
- He Is All Grown Up: It is implied that he grows into a rather handsome young man in the epilogue, which attracts Irma's interest.
- Odd Friendship: He's good friends with Nigel in both the comics and show.
- Teen Genius: Particularly when it comes to computers and technology.
- Sensitive Guy and Manly Man: The Sensitive Guy to Nigel's Manly Man.
- Smart People Wear Glasses: Martin is an Honors Student at Sheffield.
A friend of the girls at Sheffield Institute. She is around the same age as the girls, and is wholly ignorant of what Elyon and W.I.T.C.H. do.
- "Awesome McCool" Name: Let's be honest, "Alchemy" is a pretty cool name.
- Canon Foreigner: She never appeared in the comics.
- Childhood Friends: With Cornelia and Elyon.
- Crush Blush: Towards Caleb in the cartoon's first season.
- Nice Girl: Was so worried about Elyon being missing that she convinced Principal Knickerbocker to call the police. That's true friendship.
- One Name Only: Subverted, sort of. You wouldn't be faulted for only knowing her by her first name, as what is likely to be her surname (Ethel) is mentioned vaguely exactly once (in the Season 1 episode "Divide and Conquer"), by Blunk of all characters, when he's trying to delay Cedric hunting down Will (or Irma, given the red hair comment).Cedric: Tell me about the girl with red hair.Blunk: Cedric mean Ethel? Sorry, she went Denmark. Loves cheese.
- Significant Green-Eyed Redhead: Technically, Alchemy's hair is auburn, and there are many characters far more important than her in the grand scheme of things.
Irma's first serious crush early into the series, a handsome upperclassman.