Zoë Carter
The main character of Venus Envy. A 16-year-old transgender girl whose family has recently moved to the opposite side of her home state.
- A-Cup Angst: Zoe has only been on hormones for a few months and therefore is only at around Tanner Stage 2/3 in terms of breast development and uses homemade pads on her bra. She nearly breaks down when a bully makes them fall out.
- Badass Adorable: Her Tai Chi has saved her life.
- Dark and Troubled Past: She was raped when she was in middle school.
- Deadpan Snarker: Frequently makes snarky comments, particularly around her mother,.
- Heroic BSoD: Zoë occasionally has panic attacks whenever she's stressed out. The two biggest examples were 1. When she visited her old school and 2. After nearly being run over by an SUV.
- Raging Stiffie: An early comic shows her desperately attempting to cover up her crotch when the school basketball team passes by completely naked.
Larson Degado
A young trans man whom Zoë first meets at group therapy.
- Big Damn Heroes: Punching Nuke in the face, stopping his attempt on Zoë's life.
- Followed up by Zoë pulling a Big Damn Heroes, saving Larson.
- Height Angst: Due to being a trans man, he's only 5'4 and is absolutely seething with rage over this.
- Hidden Buxom: He binds his breasts with bandages, leading to a hilarious moment with Lisa.
- Jerk with a Heart of Gold: Acts like an outward asshole to Zoe when they first meet, but he gradually deals with his anger issues and becomes friends with her.
- Tiny Schoolboy: Only 5'4 due to being a transgender boy, but he makes up for it in feist. The first time he meets Zoë and her date, he tries to get into a fight with them before noticing the girls are 5'10 and 5'6 respectively.
Lisa VanGough
A lesbian who goes on a date with Zoë and discovers her Transgender secret.
- Does Not Like Men: She refuses to associate with men, aside from Chris.
- Heel–Face Turn: Initially threatens to
Eric Smith
A Casanova who intends for Zoë to be another conquest, but develops more complicated feelings.
- Dark and Troubled Past: His sister's dead, he has a strained relationship with his father and his mother's gone.
Nina dell'Abade
A stage hand for the school play.
Grace Allen
- Bad Boss: She threatens to eviscerate Nuke over a minor comment.
- Evil Plan: Psychologically destroy both Zoë and Eric, to break Eric's spirit completely and send him crawling back to her side.
- It's Personal: She sees Eric's change of heart as a personal insult and wants to destroy him.
