Welcome to the page dedicated to the series of medical sci-fi games Trauma Center. List is still incomplete. Feel free to add, and beware of spoilers!
Note: Japanese version's name, if the character has one, is written in italics.
Derek Stiles (Kousuke Tsukimori)
Voiced by: Takayuki Kondo (JP), Yuri Lowenthal (EN)
- Ass-Kicking Pose: It seems to be part of routine before starting an operation.
- Book Dumb: Derek is really only kept around Caduceus because he's a genius surgeon, and definitely not for his skills as a doctor. Dr. Kasal even sends Angie along with him because he doesn't trust Derek in that regard (though it's rather pathetic that his nurse is a far better doctor than he is). Still, he gets better by Under the Knife 2, and is shown to be impressively competent by New Blood and Trauma Team (if only because you're not playing as him anymore). The first game does extensively examine this, at least. Derek's so-so bedside manner and mediocre diagnostics skills are acknowledged by other characters (he was never top of the class in med school and borrowed assignment answers) and nearly get him in very serious trouble while he's in general practice. Part of the reason he chooses to join Caduceus is because by that point he's aware his incredible surgical skills are far and away his best asset and an environment that focuses him on that exclusively will allow him to do the most good.
- Bunny-Ears Lawyer: Is lazy and negligent a lot of the time, but is a skilled surgeon where it counts and has the ability to slow down time
- Catchphrase: Let's begin the operation!
- Healing Hands: The Healing Touch counts as this.
- Heroic BSoD: After failing to save Emilio's life. It's so bad that he actually loses the use of his Healing Touch for a while.
- The Intern: Averted, the games start with him having just finished his residency.
- Last Minute Hookup: With Angie, in the second game.
- Legendary in the Sequel: Maybe not legendary, but still, his actions in treating GUILT and PGS have made him known as a master surgeon in New Blood.
- My Greatest Failure: Just when he's operated on several patients and is ready to save him, Emilio's antibodies aren't enough, and dies. Derek doesn't take it very well.
- One of Our Own: He gets infected with GUILT in Second Opinion and has to be operated on by Dr. Kimishima.
- Power-Strain Blackout: The first time he uses the Healing Touch intentionally in an operation (as opposed to a low-stakes practice session or out of sheer desparation), he faints afterwards.
- Previous Player-Character Cameo: Appears in an episode of New Blood and a postgame challenge, and can be heard in some of Naomi's flashbacks in Trauma Team and he and CR-S01 discuss Rosalia taking on the disease she had.
- Pride: Becomes increasingly more vain in the second game, as his newfound fame leads him to believe that his Healing Touch makes any operation a non-issue. Failing to save Emilio deals a heavy blow to his confidence.
- Shut Up, Hannibal!: Every X-Mission starts with Derek openly rejecting Adam's statements.
- Super Title 64 Advance: In the English-language versions — Derek Stiles. Nintendo DS.
- Time Stands Still: He manages to do this with his Healing Touch during the Savato operations.
- Unwitting Pawn: In Trauma Center: Under the Knife 2, he becomes this for both Mercer and Reina.
Angela "Angie" Thompson Blackwell (Ange Tonegawa Amou)
Voiced by: Sachiko Nakamura (Under the Knife) and Ayako Kawasumi (Second Opinion onwards) (JP), Wendee Lee (EN)
- Alliterative Name: Ange Amou.
- Art Evolution: In the original Under the Knife, she looked a lot like a teenager despite being 21. Starting from the remake Second Opinion, she looks closer to her actual age.
- But Not Too Foreign: She is part-German.
- Clingy Jealous Girl: Despite her insistence that there's nothing between her and Derek, Angie gets noticeably more aggressive or passive-aggressive respectively when she sees Mayuzumi or Heather close to him.Angie: (to Derek, regarding Heather) You wouldn't want to make a beautiful woman like her cry, would you?Angie: (to Derek, regarding Mayuzumi) And what's more, you're all infatuated with someone like... HER!
- Easily Forgiven: Averted with her father. Even after it becomes clear that he only aided Delphi to prevent her from being kidnapped as a child and used to incubate a new strain of GUILT, she insists that he was still in the wrong for doing so and doesn't let up on her disapproval.
- Establishing Character Moment: When Angie first appears, she arrives slightly late—because she either witnessed a man on a bus having a heart attack (Under the Knife) or witnessed a man getting hit by a car (Second Opinion), and in either case, she personally helped the man to the hospital and thus was responsible for the man receiving quick treatment. This establishes how hard a worker Angie is and how seriously she takes her job, in contrast to Derek's (initial) laziness.
- Exact Eavesdropping: Whether it be on Linda reconciling with her (Linda's) parents, the fact that she could left out for a lab raid, or what's meant to be a private conversation between Derek and Mayuzumi, Angie's been scolded on more than one occasion for eavesdropping. By Under the Knife 2, Derek points out that this is a bad habit of hers.
- Foil: To Elena. While Angie is bolder and more skilled, she's rather emotionally immature and quick to anger, tears, and belittlement of others. Elena, on the flipside, is more composed, cheerier, and prefers to shower the doctors with positive encouragement instead.
- Hair-Trigger Temper: It's actually surprisingly easy to piss her off.
- Early on in Under The Knife / Second Opinion, Angie criticizes Derek for "not showing proper bedside manner" to a patient (even though all he did was tell him "we'll do the best we can"). A few chapters later, she and Derek save the life of a teenage, suicidal GUILT patient named Linda Reid. After Linda snaps at the two hospital workers for saving her, Angie loses her own temper and responds by angrily telling her that saving her was a mistake and that she should just die. Way to follow your own advice, Ang.
- Another notable example is when she berates him for an admittedly negligent decision to not properly examine a patient so he could attend a symposium, telling him that he doesn't deserve to be a doctor... and then comes crying for his help when another patient suffers cardiac arrest and she doesn't know what to do.
- I Know Karate: "I have studied Aikido."
- Jerk with a Heart of Gold: She's The Lancer, and really does care about and mean well for Derek, but good God, she is such a bitch most of the time. She berates and blames Derek for Emilio's death when in reality he was forced to make a very difficult call as a doctor during a terrorist attack-level emergency that mirrors a sadly common situation doctors go through on a near-daily basis.
- Karma Houdini: She never gets called out for her unprofessional behavior. This might not be so jarring if she weren't constantly berating Derek for not being professional enough.
- Last Minute Hookup: With Derek, in the second game.
- Shipper on Deck: A very subtle example, but after Derek cures Dr. Greg Kasal of the Tetarti strain of GUILT, Cybil says that Dr. Kasal needs time to recover, even though he'll probably try to return to work right away. So Angie suggests that it looks like they're understaffed, so perhaps Cybil could assist Dr. Kasal?
- To Be a Master: When Derek finally decides to transfer from Hope Hospital to Caduceus, Angie goes with him, both because the hospital thought Derek needed someone he was familiar with to help him, and, as Angie explains, because Angie wants to be a "master assistant" just as Derek wants to be a master surgeon.
- Trying Not to Cry: In Chapter 6 in Second Opinion, when Derek becomes infected with GUILT, Angie struggles to hold herself back multiple times. By the end of the surgery, in the Japanese version, her voice is so quiet that it barely registers above a soft whisper.
- Tsundere: The manual outright says that she "can be childish and moody from time to time". Starts out as a Type A towards Derek, but gradually warms up to him. She still shifts back every so often, though.
- By Chapter 6 in Second Opinion, when Derek becomes infected with GUILT, Angie volunteers to assist Dr. Kimishima, but at certain moments the former is unable to see Derek in the condition he was in, cries many times, and jumps to severe conclusions.
- What the Hell, Hero?:
- Delivers two of these in the first Trauma Center: Under the Knife (and its remake, Second Opinion). The first one to Derek, when Derek's carelessness in refusing to analyze a patient in detail (so that Derek could attend a symposium) caused complications later on, and the second one to Linda Reid, because Angie believes that with so many people in the hospital struggling to live, if Linda wants to die then she should die, and make room for the others.
- Delivers yet another one to Derek in Under the Knife 2 after Emilio dies. While she agrees that there was nothing that could be done about it, she also points out that Stiles' overconfidence in the Healing Touch had made him increasingly more arrogant and led him to underestimate his patients' wounds.
Nozomi Weaver / Naomi Kimishima (Mira/Mila Kimishima)
Voiced by: Akeno Watanabe (JP), Kirsten Potter (EN)
- Absolute Cleavage: Present in her Trauma Team redesign.
- All of the Other Reindeer: In a way - Nozomi was disbarred as an official surgeon for "having magical powers", which led to her jumping ship to Delphi.
- Anime Hair: It is confusing as to how her Second Opinion hairstyle is physically possible.
- Broken Bird: Her work with Delphi combined with finding out about her terminal illness makes her become this in Trauma Team.
- But Not Too Foreign: In the Japanese version, at least. She's a Japanese-American.
- She tends to begin The Summation by stating, "The dead shall speak. Let's put together the truth of what happened here." note
- In Second Opinion, she tends to say "Here Goes" before starting an operation.
- The Coroner: Takes up this role in Trauma Team as a forensic scientist.
- Defrosting Ice Queen: In Trauma Team. She was stoic and rather cold, certainly as a result of depression considering her imminent death. As her story progresses, she lightens up considerably, thanks to her interactions with Alyssa.
- Earn Your Happy Ending: After everything she gets put through, Naomi deserved getting a clean bill of health and the chance to get to take care of her adopted daughter.
- Gratuitous English: In the Japanese version. The names of her operations are in English, even.
- Healing Hands: She has the Healing Touch as well, though hers works differently from Derek's.
- HeelFace Revolving Door: Turned to Delphi after being stripped of her medical license due to her Healing Touch. As Delphi approaches its end, she then sneaks off with some GUILT samples to use as bargaining chips with Caduceus Europe, joining Derek in the battle against GUILT.
- Heroic BSoD: Naomi has one in Trauma Team when a bomb blows up in Alyssa's hands.
- One of Our Own: She is the patient for the final operation in Trauma Team.
- Mistress and Servant Boy: Her and Little Guy's relation ship in Trauma Team has shades of this.
- Ms. Fanservice: In Second Opinion. Downplayed in Trauma Team for the most part, but a lot of her cutscenes intentionally give the viewer an eyeful of boob.
- One-Note Cook: The only dish she can cook well is curry, which she learned during her time in India.
- Parental Substitute: Naomi feels obligated to raise Morality Pet Alyssa after she gets nearly killed in a bomb meant for her.
- Phone Call from the Dead: Has the ability to receive the final words of the deceased through her phone in Trauma Team, by making contact with the corpse (or its remains).
- Pop Quiz: All over the place in her portions of Trauma Team. Solving it usually leads to acquiring a Solid Evidence.
- Pre Ass Kicking One Liner: In her very first chapter on Trauma Team, when she confronts the murderer.Naomi: "I see corpses every day. One more won't bother me."
- Super Title 64 Advance: Her Second Opinion alias, Nozomi Weaver.
- Thousand-Yard Stare: Her pose when she's ready to operate in Second Opinion has her eyes look completely dead.
- Your Days Are Numbered/Soap Opera Disease: After Second Opinion, she's diagnosed with an incurable disease that leaves her with only about a year of life left, only for it to later combine with the Rosalia Virus. When she's cured of the mutated (aka "Twisted") Rosalia in the last operation, the disease dies along with it, leaving her to take care of her new adopted daughter, Alyssa.
Mary Fulton (Momoe Furumura)
Voiced by: Chisato Sugawara (Under the Knife) and Mai (Second Opinion onwards) (JP), Wendee Lee (EN)
- Catchphrase: She doesn't really have one, but fans have noted how often she berates Derek with the "You're such a handful!" line in Under the Knife 2, even if the in-game text says otherwise.
- Shipper on Deck: To Derek x Angie, in Under the Knife 2.Mary: (to Angie) There will always be times where men and women don't get along, my dear... But when you get to be my age, you start to realize just how silly it is to beat around the bush.
Tyler Chase (Tougo Sakura)
- Big Brother Instinct: Well, can you really blame him?
- Big Brother Mentor: When we're first introduced to Tyler's sister Amy, Amy hasn't done her homework because she thinks it's "boring", but Tyler explains (with a bit of self-deprecation) that if she doesn't do it, she'll turn out dumb like her big brother, and she wants everyone to know how smart she is, doesn't she?
- Brilliant, but Lazy: He's a good doctor, but he doesn't like to work very much.
- Drill Sergeant Nasty: In the sequel, he's known to be very strict with his interns, who nicknamed him "The Demon".
- Genius Ditz: Despite not liking to work very much, as noted under Brilliant, but Lazy above, Tyler is very good at writing detailed theses. Which is why Derek doesn't turn Tyler in for euthanasia after Amy is cured, as Tyler's skills can still be used to help save lives instead of ending them.
- Shipper on Deck: To Derek x Angie.
- Shoot the Dog: He was an euthanasist before Derek changed his mind by saving his little sister's life. While slightly ambiguous, it's implied that he was doing this in an unofficial (and illegal) capacity.
Victor Niguel (Shuuya Aragaki)
Voiced by: Kazuya Niinou note (Under the Knife) / Masaaki Kouda (Second Opinion onwards) (JP), Spike Spencer (EN)
- Bunny-Ears Lawyer: Is very strange and kind of a dick, but also one of the smartest people on the team, being directly responsible for synthesizing the Nanobots to destroy the Pempti GUILT and the sedative to help with the PGS symptoms.
- Cluster F-Bomb: The guy provides the greatest source for swear words in the game.
- Grumpy Bear: Stands out as a cynic in a mostly idealistic series.
- Heroic BSoD: Has a minor one after Anderson's death.
- Insufferable Genius: Though the "insufferable" part isn't played up all too much.
- Jerk with a Heart of Gold: He's not very good at showing his emotions and makes remarks that make it sound like he doesn't care. Angie calls him out on this after the operation of the sixth strain of GUILT, at which point he says he's just relieved that his colleague turned out okay. He also takes Anderson's death the hardest out of the entire cast and spends a long period of time holed up to make sure it doesn't happen again.
- Perpetual Frowner: Hardly seen smiling.
Stephen Clarks (Takuji Houshou)
- Depending on the Artist: In the stylized Under The Knife artwork, he looked severe and serious. The updated artwork shown here makes him... rather goofy.
- Game-Over Man: His main role is jumping in to take over if you fail an operation.
- The Generic Guy: He's pretty well the most nondescript member of Caduceus' staff. To underscore this, he only has one character sprite, with a neutral expression, and no voiced lines.
Leslie Sears (Yuno Itou)
- Depending on the Artist: Originally, she looked young but matronly. The updated artwork plays up her youth.
- Shipper on Deck: To Derek x Angie, in Under the Knife 2.
- You Gotta Have Blue Hair: Her green hair sticks out in a cast with mostly normal hair colors.
Sidney Kasal (Souji Kutsukake)
- Scary Shiny Glasses: More to show that he's tense than to be threatening, though.
- The Straight Man: He doesn't have much of a sense of humor, and unlike his brother, his expressions and mood are always serious.
Greg Kasal (Shin'ichi Kutsukake)
- Big Brother Mentor
- Game-Over Man: In the early operations of Under the Knife and Second Opinion, he takes over if Derek allows the patient's vitals to empty out.
- Happily Married: To Cybil, in Under the Knife 2.
- One of Our Own: He gets infected with Tetarti in the first game. He requests that Dr. Stiles perform the operation instead of Dr. Clarks, as the final test as his mentor.
Cybil Myers (Sayaka Myoujin)
Voiced by: Mizuho Adachi (Under the Knife) / Fuyuka Ooura (Second Opinion onwards) (JP), Wendee Lee (EN)
- Chekhov's Skill: Her police officer training, as she dated a guy on the bomb squad and thus, in the present day, can advise Derek on how to dismantle a bomb.
- Drill Sergeant Nasty: When Derek first meets Cybil, Tyler jokes that Cybil is this, and that she'll never work with Derek again if he screws up. This is a joke on Tyler's part, and Cybil isn't really any stricter to Derek than the rest of the cast, except when she scolds him for panicking over the bomb, but that was just to shock Derek into attempting to solve the problem.
- Happily Married: With Greg, as of Under the Knife 2.
- Nerves of Steel: Cybil got the nickname "Iron Vixen" due to her ability to remain cool under pressure.
- One of Our Own: She is infected with Paraskevi in the first game.
- Shipper on Deck: To Derek x Angie, in Under the Knife 2.
Robert Hoffman (Iichirou Kitazaki)
- Badass Beard: It becomes very spiky in his Second Opinion re-design.
- Big Good: Takes up Richard Anderson's role as head of Caduceus.
- The Comically Serious: When Cybil and Greg Kasal take off to handle the incoming patients (all being sent to Caduceus) due to a big accident on the freeway in Under The Knife 2's 3-5, they leave him to take care of their baby in the meantime. Hilarity Ensues.
- Cool Old Guy: Once he returns to wielding his Healing Touch, he is shown to be just as capable as Derek in treating GUILT.
- Let's Get Dangerous!: In Under the Knife, he wears a somewhat vacant expression on his face until this moment, when he becomes much more serious-looking. This effect is also present in Second Opinion, but it is much more subtle.
- One of Our Own: He is the patient in the final operation of Second Opinion.
- My Greatest Failure: After losing a patient in quite a messy way, he never used his Healing Touch again.
- Retired Badass: He had a Healing Touch just like Derek before... well... crap hit the fan.
Langston Miller (Lewis Willer)
OwenThe Chief Researcher at Caduceus Europe. He was in charge of a project to use "Z-Cells" from Adam's body as a regenerative treatment for patients.
- Deep Cover Agent: And a rather effective one at that. He probably could have kept the masquerade going if he didn't decide to blow his cover at the last minute.
- Obviously Evil: If the red eyes and shifty expression didn't give it away, the skull patterned tie he wears might be a clue he's up to no good.
- Slasher Smile: When he reveals his true colors.
Adam / Erick Von Raitenau (President)
- Big Bad: In the first game, but his influence is felt in Trauma Center 2 as well, and though he has no direct hand in the events of Trauma Team the final boss is the result of Rosalia mutating due to Naomi's GUILT-born genetic disorder.
- Body Horror: Just... look at him! He is a centenarian man living in suspended animation while the GUILT slowly consumes his body. When he makes his appearance in the first game, he is by all intents and purposes a zombie.
- Dark Lord on Life Support: The machine that's keeping him in suspended animation allows him to maintain his awareness and communicate past normal life expectancy.
- Evil Gloating: "No matter how hard you try, you cannot overcome the power of Death!"
- Evil Is Not a Toy: The sixth chapter of Second Opinion reveals that his body is preserved and is being used to create Z-cells that vastly improve patient recovery, even though this is essentially using Adam's unique GUILT strain for this purpose. Nozomi lampshades this trope, saying that it's bound to backfire. True enough, this ends in a GUILT outbreak at the conference, and the reveal that the scientist leading development for Z-cells is a Delphi remnant.
- Game-Over Man: If you fail one of the X operations."Mankind strives toward death...only a fool would deny that."
- A God Am I: "...I, who have become the Great Destroyer Apollyon!"
- Hypocrite: Sure, Adam, it is wrong for doctors to allow people to live longer, but when YOU make yourself immortal, it's alright... Like every good hypocrite, Adam even has a rationalization ready - he claims that, in his "undead" state, he has placed himself outside the cycle of nature, so even if he doesn't actively better the world, he doesn't take anything from it either.
- Immortality Seeker: He is also sustained by a secret eighth GUILT strain, "Bliss", that allows him to continue to function by the time of the game's events.
- Late-Arrival Spoiler: Second Opinion's box art displays him rather prominently on the front.
- Nietzsche Wannabe: Yet he also thinks that he's serving God — he even goes so far as to identify GUILT with the Seven Plagues of Revelation and proclaims he will smile as Derek and friends burn in Hell for opposing the Divine Plan.
- Plague Master: Develops the strains of GUILT that Delphi spreads across the world.
Kenneth Blackwell (Kyouji Amou)
Voiced by: Joji Nakata (JP)
- Anti-Villain: Sure, he may work for Adam, but he's so horribly ashamed about it that one can't help but feel sorry for him. Not to mention, the only reason he accepted to join Delphi in the first place was to protect his daughter Angie...
- The Atoner: After Derek saves his life. This role continues in the second game, where he goes to great lenghts to infiltrate the Hands of Asclepius.
- Catchphrase: "Indeed..."
- Death Seeker: Before the operation that saved his life, Blackwell believed that getting infected with Savato and dying from it was his just desserts for his crimes.
- Disappeared Dad: Until meeting him in the events of the game, Angie never knew who her father was.
- Face Framed in Shadow: He appears in episode Z-4 of Second Opinion, but his full face is not fully revealed until Derek confronts him at the climax of Chapter 5.
- HeelFace Turn: After the events of the first game, he supports Derek and Angie whenever he can.
- Reluctant Mad Scientist: He joined Delphi so that they would not use his daughter Angie as cultivation for GUILT strains.
- Reverse Mole: He joins the Hands of Asclepius in Under the Knife 2 in order to investigate their activities and uncover the origin of Neo-GUILT.
- That Man Is Dead: Insists that he no longer deserves to be called Angie's father from the moment he joined Delphi, and wishes to die from his own Savato infection.
Delphi Assistant/"Little Guy"/FBI Agent/Navel ("Little Boy")
Voiced by: Hiroki Tochi (JP), Yuri Lowenthal (EN)
- Ascended Extra: In Trauma Team, he becomes Naomi's assistant and plays a major role in every chapter he is in.
- Berserk Button: He's a music lover, so he (to Naomi's confusion) gets a little pissed when a valuable guitar gets damaged in a bombing.
- Bishōnen: Particularly in Trauma Team where his hair is styled to make him look younger.
- Dogged (Semi)Nice Guy: He has a plain crush on Dr. Kimishima, who usually either shoots him down or mocks him. However, as the player progresses through Forensics, Naomi will begin to flirt back every now and again.
- Drives Like Crazy: Averted, when speeding along a mountain road in Second Opinion, he explicitly mentions he's had training in aggressive driving. The journalist he's trying to ditch hasn't, though, and suffers the consequences.
- HeelFace Turn: Works with the FBI in Trauma Team after the fall of Delphi.
- Mistress and Servant Boy: His and Naomi's relationship in Trauma Team has shades of this.
- No Name Given: He is never referred to by his actual name.
- Refuge in Audacity: A terrorist who goes into hiding by... joining the FBI.
- Voice with an Internet Connection: Supports Naomi in her forensics investigation through a voice chat, and even helps her further inspect certain pieces of evidence.
- The Watson: When he's not running analysis or providing the analysis's results in Trauma Team, he's usually playing this role to Naomi instead.
Linda Reid (Sayoko Ooga)
- Driven to Suicide: Not that she actually did anything about it. GUILT would have done it for her.
- Dub-Induced Plot Hole: A minor example, but her age in Under the Knife 2 is listed as 17, the same as in the previous game, despite the three-year Time Skip. This is because in the first game's Japanese version, she was only 14 years old. The translation upped her age to 17, but that wasn't taken into account by the second game's translation.
- Emo Teen: In her defense, depression is a symptom of GUILT infection.
Amy Chase (Rin Sakura)
- Cheerful Child: She's usually drawn smiling, and she's pleasant and friendly to talk to. Her being a cheerful child actually becomes a plot point, as she decides to undergo a risky surgery she knows has a low chance of succeeding because she wants to live and work hard like her big brother.
- Heartwarming Orphan: Her purpose in the story is to drive home to the player how arbitrary GUILT is and how much it makes innocent people, such as sweet little girls like Amy, suffer. So the player will be more motivated to take down Adam, the guy who created the disease, rather than get emotionally invested in destroying something that essentially has no ill motives.
- Hidden Depths: She's the one who snaps her big brother out of his "death is better" mindset. How? By consenting to a difficult operation performed by Derek which doesn't have great odds of succeeding, just because she wants to live and work hard together with her big brother.
- Ill Girl: But Derek does manage to cure her eventually.
Richard Anderson (Katsuhisa Hibiya)
- Honest Corporate Executive: A rare example of a politician and corporate executive (as he's both the Secretary of Health and Human Services and the director of Caduceus) being portrayed in a wholly positive light. Of course, we don't know too much of his policies aside from his staunch advocacy for the medical field.
- Inspirational Martyr: His death and final wishes are what drive Dr. Hoffman to take charge of Caduceus and begin operating again.
Seven children from around the world that were kidnapped by Delphi and used as living incubators of the GUILT strains that Derek has been treating. In the original Trauma Center 1, they are operated on one at a time and then taken into protective custody, but in Second Opinion, this doesn't happen due to the events taking place in one expositionary cutscene.
- And I Must Scream: These kids are purposely left in a coma, on the brink of death, in order to cultivate GUILT strains.
- Ascended Extra: Emilio, in Under the Knife 2, is the one Sinner who gets a name and portrait.
- Break the Cutie: Emilio. Is orphaned and kidnapped at a young age, used as a living incubator for a terrible disease, starts suffering from liver failure as a result of hosting that parasite, gets infected with Nous during his liver transplant... When things finally start looking better for him, he gets caught up in a terrorist attack and contracts Kyriaki, ultimately succumbing to his wounds. Possibly the most tragic character in the entire series, and that's saying something.
- Sacrificial Lion: Again, Emilio. His death comes out of nowhere and sends Derek into a Heroic BSoD that lasts a whole chapter.
Voiced by: Shintaro Asanuma (JP)
- Ax-Crazy: Under the influence of the Neo-GUILT Sige, he comes close to using the Healing Touch to shank Derek with a scalpel.
- Bishōnen: His light build, full lips, large eyes and long hair make him easy to mistake for a woman.
- Broken Pedestal: Finding out that Dr. Stiles, his mentor, couldn't (or from Adel's perspective, wouldn't) operate on him shatters their friendship.
- Decoy Protagonist: The beginning of the story is told more from his perspective than Derek's, for the benefit of new players who aren't already familiar with the setting. When they have a falling out, the perspective stays with Stiles while Adel goes his own way.
- FaceHeel Turn: Because of brainwashing, but he himself admits later that it would not have worked if it hadn't exploited dark feelings he already had.
- Freudian Excuse: For his above FaceHeel Turn. It turns out he always felt it unfair that he was unable to completely help his people, while Derek and others were so successful because of access to such good resources and tools. That's why he took a fake Healing Touch and joined the dark side, so to speak, to improve his own skills.
- Good Powers, Bad People: "Dr. Stiiiiles... Do you know what else the "Healing" Touch is good for...? It's also good for... KILLING!"
- Green-Eyed Monster: His envy of Derek's Healing Touch and the feeling that he Can't Catch Up to such natural talent drives his actions for a good portion of the game.
- One of Our Own: He has to be operated on twice. The first time, Dr. Stiles is in the middle of a BSOD and can't handle it.
- Red Eyes, Take Warning: After joining the Hands of Asclepius and being granted the Healing . Since they were already brown, it can be hard to notice it.
- Slasher Smile: He shows a terrifyingly twisted grin when he goes crazy.
- With Great Power Comes Great Insanity: Sige gives him the power to use the Healing Touch. It also drives him stark raving mad when it breaks out of its dormancy.
Heather Ross (Ayaka Isshiki)
Voiced by: Mamiko Noto (JP)
- Cool Big Sis: To Emilio. Though technically his nurse, their relationship is so close and protective of one another that they both consider each other practically brother and sister.
- One of Our Own: As with many other of Derek's medical colleagues, he is forced to operate on her during the outbreak that ultimately takes Emilio's life.
- Red Eyes, Take Warning: Averted. Her eyes are significantly more red than Dr. Tulba's or Reina Mayuzumi but she is unambiguously on the heroes' side.
- Survivor Guilt: During the Elysium outbreak, she pleads with Derek to operate on Emilio first. Derek chooses to operate on her first instead, going with Emilio's belief that his GUILT antibodies should buy him some time to survive. Emilio doesn't make it, and Heather is distraught by this news.
- Trauma Conga Line: It's brushed over by how optimistic she remains, but this girl really goes through hell. First her mother falls into a coma, prompting her to become a nurse. She loses her closest patient during an outbreak that infects her and nearly takes her own life, then discovers her father had a hand in a bio-terrorist epidemic in an attempt to wake her mother, culminating in him being gunned down by a SWAT team before her very eyes.
Reina Mayuzumi (Rena Mayuzumi)
Voiced by: Yuko Kaida (JP)
- Big Bad Duumvirate: With Mercer. She provides him with resources to research GUILT, and in exchange, her company sells the parasites as steroids.
- Corrupt Corporate Executive: Is the president of a pharmaceutical company, yet seeks to make a profit by modifying and selling deadly parasites.
- Damsel in Distress: Twice. First when she is kidnapped by Delphi and infected with Pempti, then when the Aletheia awakens and attacks her heart.
- Final Boss: Kind of. She is part of the Big Bad Duumvirate with Mercer, but is merely a pawn in the grand scheme of things. By the end of it, she is betrayed when Mercer activates the Aletheia inside her, becoming the game's final patient.
- Narcissist: Agrees to have an extremely virulent parasite injected into her for the sole purpose of looking youthful.
- Obviously Evil: In case the way she talks and her smug expression weren't enough, the chapter she is introduced in concludes with her whispering that Derek is an idiot for not joining her and that her true objective was gaining information on the healing touch.
- Older Than They Look: She's 35, but looks like a young woman. This is a side-effect of being infected by a dormant Aletheia. When Aletheia activates, her old appearance comes back with a vengeance, making her look far older than she is.
- Rapid Aging: When the dormant Aletheia in her body is awakened, she suddenly shrivels into an old woman. After she is operated on, she returns to her youthful appearance
- Thanatos Gambit: When she is cornered and about to be arrested, Mayuzumi connects herself to a heart rate monitor and rigs the GUILT in The Very Definitely Final Dungeon to be dispersed should the machine stop detecting her heartbeat. This backfires horribly when an insane Mercer forces the Aletheia inside her to awaken, leading to Stiles and Angie desperately performing surgery on her to prevent the diseases from being released.
- The Vamp: Gets a little too close for comfort in her attempts to have Derek join Acropolis.
Patrick Mercer (Akihiro Nagasawa)
Voiced by: Masaaki Kousa (JP)
- Anti-Villain: Seeks to save his comatose wife on top of improving the abilities of people worldwide... through the use of a GUILT variation.
- Badass Boast: "Witness the power... of GUILT!" So badass it gets its own sound clip.
- Big Bad Duumvirate: With Mayuzumi. She provides him with funds and data on the healing touch so he can develop GUILT to be injected into HOA doctors. In exchange, he allows her company to sell the parasites as steroids and develops Aletheia to give her a youthful appearance.
- Despair Event Horizon: Crosses it when his attempt to cure his wife with Bythos nearly kills her instead. By this point, he loses any sanity he has left and recklessly activates the Aletheia within Mayuzumi, whose death would cause the GUILT to break loose. When that fails, he tries to detonate the explosives in the factory out of mad desire to end his own life, without realizing he would be dooming everyone else in there too.
- Driven to Suicide: Realizing that his GUILT research was ultimately useless in his attempt to save his wife, Mercer decides to detonate the explosives in the factory, which would kill both himself and the protagonists. He is stopped by the police, being shot through the heart before he could pull the trigger, and dies without a word.
- Love Makes You Evil: Delves into development of Neo-GUILT in hopes of finding a way to save his comatose wife.
- Sanity Slippage: Starts getting visibly unhinged after his research is exposed by Blackwell, but it's not until he tries and fails to awaken his comatose wife that he completely loses it.
- Sucksessor: He and the Hands of Asclepius gain increasing fame over the course of the second game that they begin to overshadow Caduceus even in the domain of GUILT treatment. Then the final chapter happens, where the source of increased aptitude is revealed to be his developed Neo-GUILT.
- Visionary Villain: His motivation is to change the world of medicine, and demonstrates this when the doctors under his employ learn the Healing Touch.
- Well-Intentioned Extremist: He has two objectives overall, both of which are noble in essence. He wants to improve medicine by granting doctors the Healing Touch and to cure his comatose wife. Unfortunately, the means through which he intends to accomplish these, engineering GUILT that enhances body functions, is far from ethical.
Tracy Mercer (Hiromi Nagasawa)
Patrick Mercer's wife. In a coma from an accident.
Heinrich von Raitenau
Voiced by: Atsushi Ono (JP)
- Disc-One Final Boss: His arrest brings about the downfall of the Delphi remnants, but there is another power at hand regarding GUILT research...
- Evil Cannot Comprehend Good: Seems to genuinely believe that the GUILT will ultimately bring about a prosperous society. Derek outright tells him that he is done trying to reason and can only feel sorry for him.
- Evil Laugh: So evil, it gets its own sound clip!
- Good Hair, Evil Hair: Evil hair, evil hair!
- Offing the Offspring: Or using them as GUILT living incubators, which is even worse.
- Overlord Jr.: Attempts to follow in his grandfather's footsteps in reviving Delphi.
- Plague Master: Like his grandfather before him, he commands the Delphi remnants in trying to spread GUILT around the world.
Voiced by: Rikiya Koyama (JP), Troy Baker (EN)
- The Atoner: Not for an intentional misdeed, but his research was misused to create Stigma, so he is partially responsible for Stigma's existence.
- Kick the Son of a Bitch: He refuses to let Vahkushti blame his actions on anything but himself and pretty much tells them to just shut up and die already.
- The Knights Who Say "Squee!": A mild example as he's too serious to squee, but he does have high respect for Derek, and mentions there's a lot of things he'd like to ask a master surgeon like him.
- No Sense of Direction: Not as bad as some comical cases, but Valerie points out he has all the cardiac blood vessels memorized, but can't follow street directions.
Voiced by: Yumi Touma (JP), Kimberly Brooks (EN)
- Ambiguously Brown: She has fairly dark skin, but you can't really attribute any specific ethnicity to her based on her looks.
Voiced by: Ryoka Yuzuki (JP), Karen Strassman (EN)
- Ascended Fangirl: In-universe. She went into medicine after being inspired by Markus performing surgery on her as a child, and is utterly delighted when she ends up as her hero's assistant.
- Foil: To Angie. While Angie is bolder and more skilled, she's rather emotionally immature and quick to anger, tears, and belittlement of others. Elena, on the flipside, is more composed, cheerier, and prefers to shower the doctors with positive encouragement instead.
- Unfortunate Names: "Salazar" is not only the given name of one fictional villain (Salazar Slytherin) and the family name of two others (both named Ramon Salazar), but also the surname of a real-life dictatorial head-of-state (António de Oliveira Salazar, prime minister of Portugal from 1932 to 1968 and founder of the authoritarian Estado Novo regime). Not exactly the most pleasant namesakes a person can have.
- Wise Beyond Her Years: She may only be 20, but she's very wise and strong-willed for her age due to her illness, something Valerie notes.
Voiced by: Ikuya Sawaki (JP), Dan Woren (EN)
- One of Our Own: He has to have tumors extracted from his small intestine. He retires soon afterwards (He had planned on doing this anyway, but his surgery sped up his decision).
Voiced by: Shinobu Sato (JP), Mona Marshall (EN)
Voiced by: Yuri Lowenthal (EN)A helicopter pilot who transfers patients for Montgomery Memorial Hospital.
Voiced by: Hochu Otsuka (JP), Doug Erholtz (EN)
- Man on Fire: Gets caught in an act of arson, and has to be treated.
- One of Our Own: He suffers from burns and has to get a skin graft.
- Red Herring: He acts like such a jerk the player will probably assume he's up to no good and is going to screw someone over. Then it turns out later on that he's the one who gets victimized, and he has to be treated for skin burns after being attacked.
- Smug Snake: His default expression is a smug smirk, and his haughty attitude does not go unnoticed by the protagonists.
Voiced by: Matsuri Kawatoko (JP)A doctor at Concordia Medical Institute.
Voiced by: Shozo Iizuka (JP), Michael McConnohie (EN)
- Laser-Guided Amnesia: His memory regresses significantly after his mind-control device is disabled.
- One of Our Own: He's the patient of the first Stigma operation, with Cheir on his heart. Later, you have to deactivate a mind-control device implanted in his brain.
Voiced by: Gara Takashima (JP), Mary Elizabeth McGlynn (EN)
- Awesomeness by Analysis: Is the first character to notice Markus is hiding something, possibly about Stigma. Irene notices by looking closely at Markus's body language. She gently but firmly tells him to be more honest and trusting with the team.
- Big Good: Since the first moment she's onscreen, she's shown to be a virtuous, if not shrewd (invokes Federal government authority to get them to join Caduceus, as a form of conscription) surgeon: she always regrets putting Markus and Valerie in the middle of danger and is usually sympathetic and supporting to them. That degree in Psychology helps.
- Cutting the Knot: In light of the new threat of Stigma, Irene pulls rank to recruit Dr. Vaughn and Dr. Blaylock immediately.
Voiced by: Kaori Akashi (JP), Karen Strassman (EN)
- Jerk with a Heart of Gold: Starts out with polite respect for the heroes, but is otherwise being very distant and cold. She grows out of it quickly after they save her cousin from a car accident and they escape from their captors. During both of these events, she harbors intense guilt for yelling at her cousin Koshiro so harshly and for being unable to help Markus and company when they are kidnapped.
- Scary Shiny Glasses: When she gets mad or serious.
Voiced by: Sanae Kobayashi (JP)A nurse at Caduceus USA.
Voiced by: Masuo Amada (JP), Greg Eagles (EN)Caduceus USA's chief surgeon.
- Game-Over Man: Usually the person who takes over if you screw up.
- One of Our Own: The very first thing you do upon meeting him is perform an emergency surgery on his cholelithiasis.
- Too Dumb to Live: Not exactly this trope, but Irene Quatro mentions he has been in pain from his gallstones for three years.
Voiced by: Tomohisa Aso (JP), Kirk Thornton (EN)Head of research at Caduceus USA. Talks in a very long-winded manner with lots of scientific-sounding words.
- Opaque Lenses: His eyes are never seen.
Voiced by: Derek Stephen Prince (EN)The president of Humani, a medical corporation that's partnered with Caduceus.
Voiced by: Karen Strassman (EN)A representative of Humani.
Voiced by: Mamiko Noto (JP), Wendee Lee (EN)
- The Mole: Has been revealed to be serving as one for Parnassus, the organization behind Stigma development.
- Restraining Bolt: Vakhushti installs a chip in her heart that allows him to kill her at a moment's notice, to control her movements.
- Rule of Symbolism: When Valerie and Markus find her trapped in her religious fanatic boyfriend's castle, she isn't wearing the ornamental cross she had been wearing for the greater part of the story.
- Walking Spoiler: Her ultimate role in the story is not revealed until the final few chapters.
Gloria MendesThe Secretary of Homeland Security.
George MarshallThe Deputy Secretary of Homeland Security.
Voiced by: Kenji Hamada (JP), Derek Stephen Prince (EN)A skilled surgeon who knows the Healing Touch and performs operations live for the TV show "Miracle Surgery". Highly critical of Caduceus.
- Cooking Duel: Bizarrely, a surgery duel.
- Fake Ultimate Hero: He unveils his Healing Touch (slow-time flavor) to much fanfare, but it appears to be rather weak - he can't sustain it for long, he passes out foaming if he does use it for too long, and it's implied Markus's is much more effective.
- Insufferable Genius: A deliberate example; he's convinced himself that if his criticism forces Valerie and Markus to improve, then it will have served its purpose. Since his criticism is completely off-base, however, this is delusional on his part.
- Smug Snake: He makes no attempts to hide the fact that he doesn't think much of Caduceus, and thinks of himself as the greatest surgeon in the country.
- Wearing a Flag on Your Head: Not in the actual game, but in his profile picture on the official site, his tie has an American flag pattern.
- Announcer Chatter: Proves to be rather talkative in Miracle Surgery.
- Combat Commentator: Or rather, "surgery" commentator, but fits nonetheless, especially given how intense surgeries can get.
- Large Ham: Comes with being an announcer. Even when he's a news reporter, he still hams it up, albeit much more subdued, given the situation.
- Most Annoying Sound: In-Universe, his loud comments about the on-going surgeries piss Markus and Valerie off.
- No Indoor Voice: Always seems to yell everything he says, much to Valerie's chagrin. He mellows out considerably when he's later seen reporting on the Stigma outbreak.
Zachariah "The Kid" Kidman
Voiced by: Wotoya Kawano (JP), Doug Erholtz (EN)A mysterious criminal who wants to profit from Stigma by selling it as a biological weapon.
- All There in the Script: His first name is never actually spoken in the game.
- Arms Dealer: Gets involved with Stigma when attempting to sell it as a weapon.
- Karmic Death: He wanted to make money out of Stigma by selling it as a weapon, but as a result, he got caught up in the conflict that was rising in Culuruma, and died in one of the battles. For extra irony, he also got infected with two strains of Stigma prior to his death.
- Psychopathic Manchild: He attempts to drown the heroes to death by sealing them in a contraption based off a kid's toy!
Voiced by: Yuri Lowenthal (EN)An intimidating man working for Kidman. He oversees Markus and Valerie's operations and gives them the serum to treat Onyx.
Voiced by: Daisuke Kirii (JP)A shady man who snuck into Concordia Medical Institute. He was later hired to kidnap Markus, Valerie, and Elena for Kidman. He tried to run away afterwards, but was shot down and had to be operated on.
- Chekhov's Gunman: First seen trying to get drugs off Concordia, only to get turned away. He reappears as one of Kidman's minions.
Voiced by: Karen Strassman (EN)A young doctor in training from Culuruma.
- One of Our Own: Operated on for her Vaimahse Fever shortly after her introduction.
- What an Idiot!: In-universe. Markus and Valerie call her out on skipping her Vaimahse Fever immunizations for very flimsy reasons (she believed she was already immune to the disease as she was born and raised in Culuruma) when she really should have known better.
President Moreno (Javier Chaves)President of the South American country of Culuruma.
- Does This Remind You of Anything?: In the Japanese version, this controversial South American president is named Javier Chaves. He's the only character from New Blood whose name was changed in the English version.
- Reasonable Authority Figure: He genuinely appreciates Caduceus's help and supplies everything they need. While he does twist their arm to force them to treat his soldiers, he willingly negotiates terms with Markus over it.
Ramsey RamirezA former Major General who leads the Culuruma Liberation Front.
Voiced by: Jurota Kosugi (JP), Derek Stephen Prince (EN)The leader of Parnassus. Real name: Ray Kerensky.
- Contrasting Sequel Antagonist/Foil: To Adam - Adam was a psychotic Nietzsche Wannabe Omnicidal Maniac, while Vakushti was more of a Woobie, Destroyer of Worlds who maddened into misanthropy after his government basically stabbed him in the back.
- Chekhov's Gunman: Goes by a pseudonym of "Ray Kerensky", head of an implant manufacturer who advised Markus on an operation that took place in the game's early chapters.
- Death Equals Redemption: Defied by Markus, who pretty much throws his speech of penance back in his face and tells him to die already.
- Famous Last Words: "Dr. Vaughn... Dr. Blaylock... Thank you... You've saved me... I was able to repent... before my death..."
- Freudian Excuse: He went crazy because, after realizing his dream of becoming a doctor and coming back home to treat refugees, the army tried to have him assassinated. He then mistakenly assumed everyone in the world was like the people who betrayed him, and he decided that humanity's only true purpose was chaos.
- Load-Bearing Boss: Cardia was the only thing keeping him alive.
- The Man Behind the Man: Revealed to be the one who ordered Professor Wilkins's kidnapping and continued Stigma development.
Resurgam First Care
CR-S01 / Erhardt Muller
Voiced by: Takahiro Sakurai (JP), Nolan North (EN)
A select few people have given him the Fan Nickname 'Numbers' as well.
- All There in the Manual: His real name is only revealed in the Japanese guidebook.
- Amnesiac Dissonance: Played with—he's aware of his previous crimes, but without any knowledge of why he committed them, this only drives him to become The Atoner. Later outright subverted when it turns out "his" previous crimes weren't even his in the first place.
- Badass Normal: Unlike his predecessors, who have the "Healing Touch", he has no special powers, but is still able to save patients' lives.
- Bishōnen: He has a really androgynous and handsome face.
- Boxed Crook: He is let out to perform surgeries in order to reduce the length of his sentence.
- Catchphrase: Let this disease pass from this world... note
- Dark and Troubled Past: Hated by his birth parents and framed for a genocide by his adoptive father, which led him to be sentenced to 250 years in prison when he was at the low age of 16.
- Deceased Parents Are the Best: Subverted. His biological parents despised him for his "lack of emotion" and thought that he'd "kill them one day". His adoptive father, Albert Sartre, treated him better than his real parents.
- Determinator: If you're a patient of his, he will cure you. No exceptions.
- Everyone Calls Him "Barkeep": He's never addressed by his serial number, but settles to being called "Doctor" or "Kid".
- Human Popsicle: Kept within a refrigerated cell where the temperature is kept at zero degrees Celsius (AKA 32 degrees Fahrenheit, at which water freezes), in order to inhibit the growth of bacteria. Gabriel ironically points out that several forms of bacteria can still be grown at this temperature.
- Inconvenient Hippocratic Oath: It happened twice. The first time it happened, CR did not think to escape, although Ian thought he would. The second time, the trope is invoked word for word. CR sees Ian on the surgery side and the exit on the other. In both cases he chooses to help the patient.
- Instant Expert: Goes from 8 years in cryogenic prison to the operating room perfectly able to save lives, despite the fact that he was imprisoned at the age of 16 and would not have been allowed to practice surgery since then.
- Longer-Than-Life Sentence: After the Cumberland incident, CR-S01 was arrested and received a 250-year life sentence.
- No Name Given: Was only by his prisoner number, CR-S01. Japanese materials note his actual name as Erhardt Muller.
- Not So Stoic: It's revealed in a bonus clip that the reason he doesn't smile is because he's spent so much time in a cold atmosphere that he actually has difficulty smiling. Said bonus clip features him practicing trying to smile and act friendly, with hilarious results.
- Parental Abandonment: Besides his parents, who died inexplicably, his adopted father vanishes at the same time as he is sent to prison.
- The Stoic: Hardly ever changes his expression.
- Troubled, but Cute: Which is subverted in his bonus scene.
- The Unsmile: He has a hard time smiling.
- When He Smiles: In the English guide manual/Japanese cover and his epilogue before the final episode, he is shown to be capable of smiling. Cue the squealing of fangirls.
Voiced by: Shizuka Ito (JP), Stephanie Sheh (EN)
- Alliterative Name: Tomoe Tachibana.
- Arranged Marriage: Tomoe's father nearly forces her into one in order to decide the clan succession. Luckily she manages to get out of it thanks to the timely intervention of Chief Patel & Gabe and her father's lung condition suddenly acting up.
- Catchphrase: "The way of honor." note
- Ninja Pirate Zombie Robot: She's one-third endoscopy specialist, one-third ninja, and one-third Samurai with crazy warping skills. Her Path of Honor is no joke, that's for sure.
- Non-Idle Rich: She chose to be an endoscopist, despite being heiress to one of the richest clans in Japan.
- Ojou: Heiress to a wealthy family.
- Rebellious Princess: Downplayed; rebellious non-royal heiress.
- Yamato Nadeshiko: Defied. She rebelled against her Japanese heritage by studying abroad in America. Ironically, however, she has the personality down pat; she defies the trope only because she's not committed to her family above all else.
Voiced by: Masashi Sugawara (JP), Dave B. Mitchell (EN)
- The Big Guy: This is even the name of his first mission.
- Butt-Monkey: He (as Captain Eagle) is hated by the public, no one at the hospital understands his mindset of good and humanitarianism, and Claire, his patient for whom he truly cares, is shot in a freak mall shooting (though she got better).
- Catchphrase: Rock solid! note
- Eyes Always Shut: To the point that he needs an Alertness Blink to signify that he's come out of his Catapult Nightmare.
- Gentle Giant: His defining character trait. He's The Big Guy, but he loves flowers, has a soft spot for a young patient of his, and performs operations requiring precision and caution rather than speed.
- Large Ham: Captain Eagle!
- Love Freak: I am the ambassador of love and justice!
- Made of Iron: Over the course of the game, Hank uppercuts a man through a ceiling, gets shot, and uses himself as a conduit to bridge two electrical cables. The only real casualty of all that is his clothing.
- Save the Villain: A gunman shoots several people in a shopping mall—one of them a friend of Hank's—and then leaps off a balcony and breaks his back after revealing that he was driven to his crime by despair over his apparently inoperable cancer. Hank not only protects the fallen man from the angry crowd, he personally operates on the man's damaged spine and extracts the cancerous tumors from his spinal cord.
- Superhero: Takes on the identity of Caotain Eagle to fight crime in his spare time. Thanks to his clumsiness and recklessness, he is also a Hero with Bad Publicity.
Voiced by: Hitomi Nabatame (JP), Amanda Winn-Lee (EN)
- Action Girl: Maria Torres has the most frantic gameplay of any character in Trauma Team, since she has to treat multiple patients at once. Her personality fits this. Bonus points for single-handedly stopping a bus from falling and crushing two other main characters.
- Ambiguously Brown: Her name implies some kind of Spanish or Hispanic descent.
- Cluster F-Bomb: Cluster D-Bomb: The greatest source of swearing in Trauma Team.
- Enraged by Idiocy: Maria chides the other first responders for a number of rookie mistakes. When another comments on how they "didn't make any mistakes," she retorts that he's too soft on them. Given that in the mission immediately prior had another first responder almost accidentally move a guy skewered through the chest by a metal bar, and they almost lost a patient in the same cutscene by using epinephrine on a cardiac arrest patient, (which was known to be an ineffective treatment even in 2010), it's understandable that she's frustrated.
- I See Dead People: She periodically sees the spirit of Rosalia warning her of things to come.
- Ms. Fanservice: Her first mission introduction features her topless, with only a towel (barely) covering her breasts.
- Pre-Mortem One-Liner: "Suck on some antivirus you bastard! You won't kill off my town!"
- Parental Abandonment: Was at the same orphanage as Rosalia.
- Teeth-Clenched Teamwork: Feels that she is Surrounded by Idiots at her workplace, but bears with them despite her frustration. She's more receptive around her fellow protagonists.
- Unwanted Assistance: In-Universe, Maria has this attitude towards her fellow paramedics.
- Who Wears Short Shorts?: She's never seen wearing any legwear longer than her thighs.
Gabriel "Gabe" Cunningham
Voiced by: Keiji Fujiwara (JP), Travis Willingham (EN)
- Badass Normal: He is the only member of the main cast that does not exhibit some form of supernatural ability. CR-S01 can survive in a place where most humans would succumb to hypothermia, Hank is Made of Iron, Naomi can hear the last words of the dead, Maria is able to see a ghost, and Tomoe's ninja training allows her to pretty much teleport. Doesn't stop him from getting plenty of badass moments on top of being one hell of a doctor.
- Berserk Button: In the episode 'The Simplest Truth', RONI finally pushes it. Seems like ever since an incident of his past, Gabe doesn't take kindly to be doubted or called out for not being honest with himself or others.
- Breaking the Fourth Wall: Does this in the epilogue.
- Chewing the Scenery: Gabe tends to be over the top normally, but pronounced during "Proud One", when Gabe is unable to run a diagnosis on Samuel, since the military is covering up what happened to him. Spyware within RONI prevents him from making any diagnosis, but he is able to have "friendly chats" and make "meaningless friendly observations." Taken to epic levels when Gabe gets Samuel to take his shirt off.
- The Chew Toy: Let's see here: He was almost hit by an arrow in Tomoe's storyline, got hit by a bus at a mall, his 'safe' landing got him in the trash at the last chapter, etc. The developers surely love messing with him, and for our amusement.
- Dreaming of Things to Come: Implied to have a dream about the Rosalia outbreak when he is first introduced.
- Dr. Jerk: A mild case compared to Victor of Second Opinion, but still.
- Finger Gun: In case the Spike Spiegel shout-out wasn't obvious enough, he strikes this pose when he's escaping on the helicopter.
- Lethal Diagnosis: Patents start out only suffering from one or two mild symptoms such as a cough, fatigue, moments of disorientation, etc. after being diagnosed are told they have some kind of tragic disease. Thankfully CR-S01 is more then a match for any disease.
- Meaningful Name: Dr. Cunningham is nothing if not cunning.
- No Smoking: He smokes a lot in the actual game, but his cigarette is absent in much of the publicity material.
- Suicidal "Gotcha!" Does this when trying to escape to create a diversion, complete with the Spike Spiegel Bang gesture.
- Team Dad: Sure, he has his own issues, but he has a heart-to-heart with just about every other member of the team at some point during their storylines.
Voiced by: Mayumi Asano (JP)
- Trademark Favorite Food: She seems to be really fond of Italian.
Darnell Sellers & Emma Wilson
Voiced by: Shintaro Asanuma (Darnell, JP) & Eri Kitamura (Emma, JP), Orion Acaba (Darnell, EN)
- Those Two Guys: Recurring background characters in various scenes throughout the game.
Voiced by: Yurie Yamashita (JP)
- The Anti-Nihilist: She becomes this following her Character Development.
- As You Know: Her programming requires her to give a short tutorial the first time she uses a feature, even if the user is a trained doctor.
- Literal-Minded: Takes a while to pick up on Gabe's figures of speech.
- Ms. Exposition: Explains a lot of her functions and tests to Gabe (and the player) during the Diagnosis missions.
- Mundane Utility: In Gabe's bonus scene, RONI is used as a cooking guide.
- Robot Buddy: Designed to function as one to her assigned doctor.
- Voice with an Internet Connection: Quite literally, as she assists with tests, procedures, and diagnosis.
Voiced by: Jurota Kosugi (JP), Keith Silverstein (EN)
- It's Personal: Subverted. His wife and daughter were killed in the Cumberland College attacks, but he watches over CR-S01 simply because it's his job, and has long since decided CR-S01 isn't the real culprit.
- Sinister Shades: Never seen with his sunglasses off, and it makes him look more intimidating when combined with his cold attitude towards CR-S01.
Voiced by: Rinko (JP), Laura Bailey (EN)
- Fanservice: Minor example, but at one point in order to examine her, Dr. Gabriel Cunningham has to ask her to lift up her shirt so she can examine her breathing. The player gets to see her bra while she's doing this, and RONI has to scold Cunningham by pointing out that this is embarrassing the patient and Dr. Cunningham needs to be more tactful.
- Growling Gut: On the second examination her gut growls. Gabe notes that it is perfectly normal to be hungry.
- Ordinary High-School Student: Apart from her ambitious music aspirations, of course.
Voiced by: Kimiyoshi Kibe (JP), Harvey Atkin (EN)
- Chekhov's Boomerang: He aids Gabriel in letting him escape from the USAMRIID building while he faces charges for breaking the rules of the examination.
- Eyes Always Shut: Lampshaded and parodied. It causes problems for Gabe when he can't tell if his eyes are jaundiced.
- Fan Disservice: Gabe has to examine this insufferable man's Gonk body.Gabriel: 'This is not the most pleasant thing I've looked at recently...'
- Gonk: Due to his less shapely character design compared to the rest of the cast.
- Grumpy Old Man: Proves to be rather uncooperative as Gabe tries to take his medical history.
- Jerk with a Heart of Gold: All in all, he certainly has a big heart. Heck, you even get to see it when CR-S01 operates on him.
- My Country, Right or Wrong: Subverted. While he initially appears to be perfectly willing to go through with the government's plan to let a portion of the population die from the pandemic, he provides some vital assistance to help Gabe escape the army and is arrested for it.
- Patriotic Fervor: He rarely misses an opportunity to loudly proclaim how much he loves his country.
Voiced by: Eri Nakao (JP)
- Hello, Nurse!: Most of Gabe's comments when conducting a visual examination are about how attractive she is.
- Hot Librarian: According to Gabe himself.
- Married to the Job: Her initial consultation reveals her dedication to her job, and her main concerns are her ability to work.
- Ms. Fanservice: Gabe himself thinks she is attractive, and the very nature of Diagnostics means you will have to listen to her heartbeat at one point... Do the math.
- She's Got Legs: Hm... I don't think there's anything wrong with her legs. Nothing wrong at all...
- Something About a Rose: She wears a black rose brooch, and her bra also has a rose pattern on it. This foreshadows her Rosalia virus infection.
Voiced by: Hiromi Otsuda (JP), Yuri Lowenthal (EN)
- Definitely Just a Cold: Repeatedly insists that his illness is not a cause for concern, and tries to downplay his symptoms.
- Strong Family Resemblance: The only way to point at him and say he's Gabriel's son is the hair.
Voiced by: Hana Takeda (JP)Gabriel's wife. She's never actually seen and only talks to him over the phone.
- The Voice: Never pictured, only heard.
Voiced by: Daisuke Kirii (JP), Yuri Lowenthal (EN)
- Classified Information: He refuses to allow Gabe to do anything until his superiors give the go ahead.
- Fatal Family Photo: He mentions having a wife and daughter. As the diagnosis progresses, he gets much, much worse. By the end of it, he only pulls through thanks to his desire to see his family again.
- Heroic Build: Gabe notes that he has a rather good-looking body. There's even a Doctor Medal for noting how well he's built compared to a normal person. The Rosalia Virus just makes his body look worse by the minute.
- Heroic Sacrifice: His infection causes him unspeakable pain, but he endures it and begs dr. Cunningham to proceed with the diagnosis, believing that whatever information Gabe finds out about his illness would help treat other patients.
- Incurable Cough of Death: As his condition worsens, he starts coughing so hard he vomits blood. This actually proves helpful to pinpoint exactly what disease he has.
- Killed Offscreen: It's heavily implied that he died shortly after his diagnosis.
- Lethal Diagnosis: Is suffering from some mild symptoms before his introduction. As soon as his diagnosis begins, he starts to get much, much worse...
- Mr. Fanservice: Earns some compliments from Gabe regarding his muscles, and you get to examine his body just like any other patient in Diagnosis. Then subverted to hell and back when the Rosalia virus causes him to start bleeding profusely from his chest and abdomen.
- Sacrificial Lion: One of the most sympathetic characters in the game. His one purpose is to show the horrendous symptoms of the Rosalia Virus as he visibly gets worse and worse during his diagnosis.
- Uncertain Doom: Whatever happened to him after his diagnosis was completed is unclear, though the severity of his symptoms all but indicate that he died.
Voiced by: Koutarou Nakamura (JP)
- Badass Grandpa: To put it simply, he freakin' teleported to an airplane already flying over the clouds miles away from the ground.
- Battle Butler: Taken to insane levels, though his liege is just as good to fight.
- Bodyguarding a Badass: Tomoe can clearly hold her own against enemies, but Hanzou regardless looks after her.
- Crazy-Prepared: As expected of a very well-trained butler.
- Ninja Pirate Zombie Robot: He's part butler, part samurai, part ninja! Why can't all butlers be like that?
Voiced by: Atsushi Ono (JP)
- Meddling Parents: Despite how successful and happy Tomoe is in her vocation as an endoscopy doctor, he really wants her to take over leadership of her family's clan.
- Shirtless Scene: Just to show off how imposing he looks like.
- Strong Flesh, Weak Steel: His skin is so tough that it can't be cut by a scalpel or pierced by a needle. In order to clear an airway, Hanzou had to use a sword.
Voiced by: Yuka Iguchi (JP)
- Bandage Babe: Always seen with a bandage on her arm as she's still recovering from her injuries.
- Broken Bird: It's revealed this is why she wants to commit suicide. Her mother's relationships went lousy, and ever since, Claire's never been able to trust men, and Claire's had a lot of relationships go sour so her distrust is magnified.
- Bungled Suicide: Her suicide attempt resulted in severe injuries but was not enough to kill her, allowing Hank to save her life.
- Emo Teen: Though she is 20, she still carries a depressed outlook on life akin to Linda Reid. Hank makes efforts to change this outlook.
- Irony: Claire does in fact almost die when a crazed gunman shoots her at the mall...right after she finally wanted to live!
Voiced by: Hajime Iijima (JP)
- Eat the Evidence: Swallowed his stash of narcotics, which puts him in shock and sets the stage for the first Endoscopy level.
- Not So Different: He makes this claim to Captain Eagle.
Voiced by: Matsuo Matsuo (JP)
- Creator Cameo: His appearance and name are based on Hirotaka Mizuno, one of the game's programmers.
- Despair Event Horizon: His "horizon" was when he found out his cancer would kill him, and he felt that nobody else around him appreciate the lives they took for granted, which he considered an injustice since his own life would soon be cut short.
Voiced by: Yasuhiro Mamiya (JP)
Voiced by: Mika Takashita (JP)
- Cheerful Child: Pity that she got bombed.
- Chekhov's Gunman: Alyssa's introduced as comic relief in Naomi's third in-game murder case, but she shows up again later and helps solve the mystery by discovering that a clock was broken...because there was something inside. The real murder weapon, to be precise.
- Happily Adopted: Naomi becomes her guardian at the end of the game.
Unknown voice actors
The victim in the second Forensics case.
- Abusive Parents: Peculiar in that their abuse was in direct response to the way she treated them. Veronica's growing mental instability caused her to physically assault her own parents, who became increasingly terrified of her violent outbursts. As her symptoms worsened, they decided not to take her to a doctor and actually locked her in her room, where she ultimately dies from a seizure.
- Family-Unfriendly Death: She died clawing her bedroom door until her hands bled, screaming for her parents' help and vomiting blood uncontrollably.
- Meaningful Name: "Cage" is certainly a fitting name for someone who was kept locked up in her room.
- Tragic Villain: She was horrible to her parents, but it's impossible not to feel sorry for her given that her behaviour resulted from the emotional and physical pain brought about by the Rosalia virus, not to mention the horrific way she died.
- Troubled Abuser: The emotional instability and increased aggression caused by her illness, made worse by the psychological strain from the physical pain she was in, prompted her to repeatedly lash out at her parents with physical violence.
The victim in the third Forensics case.
- Accidental Murder: How she actually died. Her husband woke up prematurely from his drug-induced sleep and murdered her in self-defense, without realizing his attacker was actually an insane Alma.
- Apocalyptic Log: Her diary goes into detail on how she gradually started to lose her sanity.
- Driven to Madness: The Rosalia virus attacks her brain, causing her to hallucinate and shattering her grip on reality.
- God Is Displeased: She interprets the various symptoms she is suffering from as the result of divine punishment.
- Meaningful Name: Alma means "soul" in Spanish and Portuguese. She was trying to murder members of her family because she believed it would save their souls.
- My Greatest Failure: Alma tearfully blames herself when she hallucinates God telling her that the daughter she just murdered failed to reach Heaven.
- Reasoning with God: She believes she is doing this, when in reality she is just talking to herself.
- Soul Saving Crusader: She would be the definition of this trope if her actions hadn't been influenced by Rosalia virus-induced madness.
- Sympathetic Murderer: It's hard not to sympathize with her when everyone comments what a lovely person she was before the fateful day when she was infected with the Rosalia virus.
- Tragic Villain: Yes, she is an antagonist, but no matter how you look at it her actions were always beyond her own control.
Unknown voice actors
A college student that turned out to be being paid money to record voice threats for Sandra Lieberman, the Raging Bomber.
- Asshole Victim: Few sympathies were had once his role in the Raging Bomber's plots was discovered.
- Blackmail Backfire: He tries to blackmail Sandra who has him killed off in revenge, after abiding by his increased demands once.
- Death by Irony: Sandra, in order to orchestrate the above trope, had Eldred (vaguely) describe himself ("the next target will be a Caucasian male") in his final bomb threat before having him killed off.
- Loan Shark: Took out a massive loan to afford a vintage guitar.
- Tonight, Someone Dies: The theme of his bomb threats.
Voiced by: Rei Igarashi (JP), Laura Bailey (EN)
- Ax-Crazy: Courtesy of the Rosalia Virus.
- Blackmail Backfire: She killed Eldred in revenge for a blackmail attempt.
- Death by Irony: Having Eldred describe himself ("a Caucasian male") before sending the bomb to him.
- Criminal Mind Games: She sets up a quiz puzzle game in her suspected house for Naomi, and Naomi must put in an 8-digit number into each bomb without making too many mistakes. Make too many, and Game Over.
- Deadly Delivery: She delivers her bombs personally.
- Fan Disservice: She exposes her naked body (with explosives covering her privates) when confronted by the authorities. Too bad by this point her body is deteriorated and covered with bruises thanks to the Rosalia virus.
- Kaizo Trap: Sets one up against Naomi during the deadly puzzle game in her house. Thankfully, the doctor sees right through it.
- Killed Mid-Sentence: Is gloating to Naomi when the Rosalia virus triggers hemorrhages all over her body. This causes her to drop the controller to the explosives strapped around her body, with predictable results.
- Mad Bomber: Goes without saying, considering her method of operation.
- Serial Killer: Commits several terrorist acts, with her latest targets being Naomi Kimishima and the queen of England.
- Suicide Attack: In her last terrorist attempt, she straps the explosives to her own body. Averted in that she doesn't voluntarily pull the trigger, the explosion happens by accident.
Mysterious Girl/Rosalia Rossellini
Voiced by: Sora Kuwakado (JP), Laura Bailey (EN)
- Everyone Went to School Together: Was an orphan in the same orphanage as Maria.
- Famous Last Words: Can also be subverted as a Catchphrase as she says throughout Maria's story: Beginning...
- The Immune: The Rosalia Virus infection she harbors prevents other pathogens from causing disease in her.
- Meaningful Name: Could be a reference to Rosalia Lombardo, a two year old Italian girl who died in 1920 and whose corpse is now one of the most well-preserved specimens to this day, and/or Saint Rosalia of Palermo, whose legend involves a plague coming to an end when her body is recovered.
- Mysterious Waif: Appears from time to time, speaking of a "beginning". What this entails is eventually revealed in the final chapter.
- Nice Girl: From what we learn about her from the audio recordings we see of her, she seems to have been this. Her only wish was that her father, Albert Sartre, would succeed and cure everyone of disease. That she's a nice girl is also in stark ironic contrast to the fact that her deceased body almost caused an epidemic disaster.
- Person of Mass Destruction: Posthumously. Her death paves the way for the eventual Rosalia Virus outbreak.
- Posthumous Character: Long dead by the events of the game.
- Repetitive Name: Rosalia Rossellini
- Sealed Evil in a Can: She harbors the incredibly lethal Rosalia Virus in her body, which is about the worst disease there is that can disintegrate anything inside the body and cause massive bloody hemorrhages, along with dementia for those who get affected by it.
- Sealed Good in a Can: Ironically, she also possesses the same antibodies that prevent her from succumbing to the same disease and any other illness in the world, which led Albert to retrieve those sought out antibodies but unfortunately got infected while doing it. The doctors are only able to retrieve the cure from her corpse three years after Albert shot her to death.
- Unwitting Instigator of Doom: Admittedly, it's more Albert Sartre's fault for shooting her, but Rosalia's body ends up being the originating point for a disease that then gets spread by monarch butterflies and almost wipes out Portland.
- Walking Spoiler: Rather difficult to discuss without spoiling the final chapter of Trauma Team due to her role in it.
Voiced by: Yukihiro Misono (JP)
- Famous Last Words: "My son... Forgive me... I was enticed by the Devil...!"
- Mad Scientist: Mad, as in, mentally unstable. Played straight after being infected with the Rosalia Virus, which makes him lose his sanity and kill his daughter.
- Meaningful Name: Could be a reference to Dr. Alfredo Salafia, the doctor who embalmed the corpse of Rosalia Lombardo.
- Nice Job Breaking It, Hero!: Not only gets infected by the Rosalia virus trying to extract a cure from Rosalia's blood, he also manages to unleash the same virus to wreak mass terror when he tried to eliminate it.
- Posthumous Character: Long dead by the events of the game.
- Tragic Villain: Albert allows his son to take the blame for the outbreak at Cumberland College and causes the Portland pandemic by murdering his own daughter. However, all he really wanted was to transform the Rosalia virus into an universal cure, and both the stress of his research and his eventual infection by it took a toll of his sanity. He ultimately dies, alone and in agony, all the while begging Erhardt to forgive him.
- Unwitting Instigator of Doom: By shooting Rosalia near a place where monarch butterflies could get to her, Albert almost caused a terrible disease to wipe out Portland.