WARNING, MAJOR SPOILERS AHEAD
Voiced by: Yo Taichi (Japanese), Megan Shipman (English)
One of the orphans from the Hyakuya Orphanage.
- Brain in a Jar: In Chapter 46, it is revealed that Ferid preserved her disembodied head. He shows the jar to the Shinoa squad, Yu and Mika. Seeing this made Yu go berserk and try to kill Ferid.
- Curtains Match the Window: Had brown hair and brown eyes.
- Motherly Side Plait: As the oldest female, she was like a mother to the other orphans.
- Plot-Triggering Death: Her death along with other orphans was the main reason why Yu wants to kill vampires. It's also what caused Mika to constantly blame himself and become the bitter man he is today.
- Puppy Love: It is revealed in the Catastrophe Light Novels that she had a crush on Mika. Subverted in that it is one-sided.
Voiced by: Tomoyo Kurosawa (Japanese), Bryn Apprill (English)
Kimizuki's younger sister. She was infected with the Apocalypse Virus despite being a child and is being treated in a hospital.
- Ill Girl: She is infected with the Apocalypse Virus even though she is younger than thirteen.
- Superpowered Evil Side: As a seraph, she has one. She is unwillingly injected with drugs to force her to transform.
- Black Eyes of Crazy: Like Yu, both of her sclera turn black after awakening as a seraph, specifically the Fifth Trumpet, the Angel of Destruction.
- Power Gives You Wings: Gains two pairs of white feathered wings on her back after awakening as a seraph.
- Summoning Ritual: Kureto and the Japanese Imperial Demon Army summoned a demon called Abaddon, using Mirai's Trumpet and numerous blood sacrifices from humans, demons and vampires.
Voiced by: Yoko Hikasa (Japanese), Kara Edwards (English)
Yoichi's older sister, who was killed by Lacus Welt sometime after the Apocalypse began.
Guren Ichinose's father. He appears in the Seraph of the End: Guren Ichinose: Catastrophe at Sixteen light novel series as head of the Ichinose branch family.
- Good Parents: Sakae was a loving father and cared for his son's safety.
- Extreme Doormat: Sakae was submissive to the Hīragi Family and endured their abuse.
- Off with His Head!: He was executed by beheading.
- Rapid Aging: He was presumably in his 40's but aged drastically while in Hīragi captivity.
- So Proud of You: He was very proud of Guren, and told him as much many times throughout Catastrophe.
Voiced by: Yoshihito Sasaki (Japanese), Seth Magill (English)
A minor character and a student at Second Shibuya High School.
- Blatant Lies: He and his friends lie about being selected for the army in order to intimidate people.
- The Bully: He and friends were bullies at Second Shibuya High School.
- Reformed Bully: Becomes this after his and Yuu's display of heroics in defeating a vampire that attacked the school, becoming much kinder to Yoichi. He even apologizes for picking on him.
Voiced by: Rina Hidaka
A human girl that is kidnapped by a vampire named Shahal. She appears in the Seraph of the End: Vampire Reign OVA, Vampire Shahal.
- Curtains Match the Window: Has brown hair and brown eyes.
- Identical Stranger: She bore a close resemblance to Shahal's younger sister Lana, which is why he kidnapped her since he thought she was Lana.
- Stockholm Syndrome: A downplayed version. She still wanted to go home to her family but became sympathetic towards Shahal because he used to be human.